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Neuroscience

D-Index
87
Citations
24491
World Ranking
1265
National Ranking
138

Biology and Biochemistry

D-Index
89
Citations
25096
World Ranking
2601
National Ranking
187

Medicine

D-Index
88
Citations
24815
World Ranking
13288
National Ranking
1239

Research.com Recognitions

  • 2018 - Member of Academia Europaea
  • 2015 - Fellow of the Royal Society, United Kingdom

Overview

Annette C. Dolphin is affiliated with University College London in the United Kingdom. Their work spans multiple areas within biochemistry, genetics, molecular biology, and neuroscience. The scientist's research focuses primarily on ion channel regulation and function, with significant contributions to cellular and molecular neuroscience as well as cognitive neuroscience.

Their publications cover a range of topics, including presynaptic calcium channels, voltage-gated calcium channels, and neurological disease mechanisms. Recent papers include:

  • Presynaptic calcium channels: specialized control of synaptic neurotransmitter release, 2020, Nature reviews. Neuroscience
  • Functions of Presynaptic Voltage-gated Calcium Channels, 2020, Function
  • Amino acid sensor conserved from bacteria to humans, 2022, Proceedings of the National Academy of Sciences
  • Biallelic CACNA2D1 loss-of-function variants cause early-onset developmental epileptic encephalopathy, 2022, Brain
  • FMRP regulates presynaptic localization of neuronal voltage gated calcium channels, 2020, Neurobiology of Disease

The scientist collaborates frequently with several researchers, including Shehrazade Dahimène, Ivan Kadurin, Wendy S. Pratt, Krishma Ramgoolam, and Karen Page. Their work is often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Function, Cell Calcium, and Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature.

Main fields of study include biochemistry, genetics and molecular biology and neuroscience, with subfields in molecular biology, cellular and molecular neuroscience, physiology, cognitive neuroscience, and cell biology. The research covers multiple topics:

  • Ion channel regulation and function
  • Neuroscience and neuropharmacology research
  • Nicotinic acetylcholine receptors study
  • Photoreceptor and optogenetics research
  • Pain mechanisms and treatments
  • Cellular transport and secretion
  • Genetics and neurodevelopmental disorders

Annette C. Dolphin has been recognized with distinctions such as Member of Academia Europaea in 2018 and Fellow of the Royal Society, United Kingdom, in 2015. These honors reflect a sustained engagement with the scientific community in their areas of expertise.

Best Publications

  • The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential

    Gerald W. Zamponi;Joerg Striessnig;Alexandra Koschak;Annette C. Dolphin

  • Identification of the α2-δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin

    Mark J. Field;Peter J. Cox;Emma Stott;Heather Melrose;Heather Melrose

  • Beta subunits of voltage-gated calcium channels.

    Annette C. Dolphin

  • Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.

    Elena A B Azizan;Hanne Poulsen;Petronel Tuluc;Junhua Zhou

  • The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin.

    Claudia S Bauer;Manuela Nieto-Rostro;Wahida Rahman;Alexandra Tran-Van-Minh

  • Pharmacological disruption of calcium channel trafficking by the α2δ ligand gabapentin

    Jan Hendrich;Alexandra Tran Van Minh;Fay Heblich;Manuela Nieto-Rostro

  • Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels.

    Anthony Davies;Jan Hendrich;Alexandra Tran Van Minh;Jack Wratten

  • Long-term potentiation of the perforant path in vivo is associated with increased glutamate release

    A. C. Dolphin;M. L. Errington;T. V. P. Bliss

  • Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

    Annette C. Dolphin

  • α2δ expression sets presynaptic calcium channel abundance and release probability

    Michael B. Hoppa;Beatrice Lana;Wojciech Margas;Annette C. Dolphin

  • Ducky Mouse Phenotype of Epilepsy and Ataxia Is Associated with Mutations in the Cacna2d2 Gene and Decreased Calcium Channel Current in Cerebellar Purkinje Cells

    J Barclay;N Balaguero;M Mione;SL Ackerman

  • Calcium channel currents and their inhibition by (-)-baclofen in rat sensory neurones: modulation by guanine nucleotides.

    A C Dolphin;R H Scott

  • Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology.

    Annette C. Dolphin

  • G protein modulation of voltage-gated calcium channels

    Annette C. Dolphin

  • Mechanisms of modulation of voltage‐dependent calcium channels by G proteins

    Annette C. Dolphin

  • An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus.

    A.C. Dolphin;A.C. Dolphin;E.R. Archer

  • The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of α2δ subunits is key to trafficking voltage-gated Ca2+ channels

    C. Cantí;M. Nieto-Rostro;I. Foucault;F. Heblich

  • Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.

    A C Dolphin;S R Forda;R H Scott

  • A short history of voltage‐gated calcium channels

    Annette C Dolphin

  • Pertussis toxin reverses adenosine inhibition of neuronal glutamate release.

    A C Dolphin;S A Prestwich

Frequent Co-Authors

Peter Jenner
Peter Jenner King's College London
Charles David Marsden
Charles David Marsden King's College London
Anthony H. Dickenson
Anthony H. Dickenson University College London
Tim V. P. Bliss
Tim V. P. Bliss The Francis Crick Institute
Edward Perez-Reyes
Edward Perez-Reyes University of Virginia
Bernd Nürnberg
Bernd Nürnberg University of Tübingen
Bonnie A. Wallace
Bonnie A. Wallace Birkbeck, University of London
Rafael Luján
Rafael Luján University of Castilla-La Mancha
Robert C. Ford
Robert C. Ford University of Manchester
John Wood
John Wood University College London

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