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Biology and Biochemistry

D-Index
86
Citations
29603
World Ranking
2940
National Ranking
217

Overview

Matthew Whiteman is affiliated with the University of Exeter in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant work also in medicine. The subfields of study within their portfolio include biochemistry, physiology, molecular biology, endocrine and autonomic systems, and epidemiology.

The main topics explored in Whiteman's work cover sulfur compounds in biology, neuroscience of respiration and sleep, adipose tissue and metabolism, liver disease and transplantation, amino acid enzymes and metabolism, obstructive sleep apnea research, and renin-angiotensin system studies.

Whiteman has published extensively, with recurrent appearances in several scientific journals. The principal publication venues for their work include:

  • Proceedings of the National Academy of Sciences
  • Redox Biology
  • International Journal of Molecular Sciences
  • Antioxidants and Redox Signaling
  • Pharmacological Research

Frequent collaborators in Whiteman's research network include Roberta Torregrossa, Mark E. Wood, Bartosz Pomierny, Alicja Skórkowska, and Luke Slade.

Examples of recent publications authored or coauthored by Whiteman are:

  • Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation (2021), Proceedings of the National Academy of Sciences
  • Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization (2020), Journal of Advanced Research
  • Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration (2020), Cell Metabolism
  • The Slow-Releasing and Mitochondria-Targeted Hydrogen Sulfide (H2S) Delivery Molecule AP39 Induces Brain Tolerance to Ischemia (2021), International Journal of Molecular Sciences
  • Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model (2021), Proceedings of the National Academy of Sciences

Best Publications

  • Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

    Barry Halliwell;Matthew Whiteman

  • Characterization of a Novel, Water-Soluble Hydrogen Sulfide–Releasing Molecule (GYY4137): New Insights Into the Biology of Hydrogen Sulfide

    Ling Li;Matthew Whiteman;Yan Yi Guan;Kay Li Neo

  • Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse

    Ling Li;Madhav Bhatia;Yi Zhun Zhu;Yi Chun Zhu

  • The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite ‘scavenger’?

    Matthew Whiteman;Jeffrey S. Armstrong;Siew Hwa Chu;Siau Jia-Ling

  • Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide?

    M Ali;CY Ping;Y-Yp Mok;L Ling

  • The gastrointestinal tract: A major site of antioxidant action?

    Barry Halliwell;Kaicun Zhao;Matthew Whiteman

  • Chlorinative stress: an under appreciated mediator of neurodegeneration?

    Yann Wan Yap;Matthew Whiteman;Nam Sang Cheung

  • Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents.

    Peter Rose;Matt Whiteman;Philip K. Moore;Yi Zhun Zhu

  • Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels

    Claire M. Williams;Manal Abd El Mohsen;David Vauzour;Catarina Rendeiro

  • Progressive multifocal leukoencephalopathy in 47 HIV-seropositive patients: neuroimaging with clinical and pathologic correlation.

    M. L. H. Whiteman;M. J. D. Post;J. R. Berger;L. G. Tate

  • Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain?

    Matthew Whiteman;Nam Sang Cheung;Yi-Zhun Zhu;Siew Hwa Chu

  • The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

    Matthew Whiteman;Ling Li;Peter Rose;Choon-Hong Tan

  • Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide.

    Matthew Whiteman;Ling Li;Iouri Kostetski;Siew Hwa Chu

  • Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies.

    Barry Halliwell;Kaicun Zhao;Matthew Whiteman

  • A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?

    Xu Cao;Lei Ding;Zhi-zhong Xie;Yong Yang;Yong Yang

  • Antioxidants in Chinese herbal medicines: a biochemical perspective

    Y. Z. Zhu;S. H. Huang;B. K. H. Tan;J. Sun

  • Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising.

    Matthew Whiteman;Paul G Winyard

  • Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools.

    Matthew Whiteman;Sophie Le Trionnaire;Mohit Chopra;Bridget Fox

  • Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats.

    Yi Zhun Zhu;Zhong Jing Wang;Peiying Ho;Yoke Yun Loke

  • AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

    Bartosz Szczesny;Katalin Módis;Kazunori Yanagi;Ciro Coletta

Frequent Co-Authors

Barry Halliwell
Barry Halliwell National University of Singapore
Philip K. Moore
Philip K. Moore National University of Singapore
Paul G. Winyard
Paul G. Winyard University of Exeter
John T. Hancock
John T. Hancock University of the West of England
Csaba Szabó
Csaba Szabó University of Fribourg
Jeremy P. E. Spencer
Jeremy P. E. Spencer University of Reading
Madhav Bhatia
Madhav Bhatia University of Otago
Milos R. Filipovic
Milos R. Filipovic Leibniz Institute for Neurobiology
Paul Eggleton
Paul Eggleton University of Exeter
Weihua Liu
Weihua Liu Tianjin University

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