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D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
16178
World Ranking
7071
National Ranking
3249

Overview

Ye-Shih Ho is a researcher affiliated with Wayne State University in the United States. Their work primarily spans the fields of medicine and biochemistry, genetics, and molecular biology. Within these broad areas, their subfields include epidemiology, molecular biology, physiology, pharmacology, and aging.

Their research focuses on several key topics, including autophagy in disease and therapy, peroxisome proliferator-activated receptors, ginger and Zingiberaceae research, genetics, aging and longevity in model organisms, tryptophan and brain disorders, adipose tissue and metabolism, and lipid metabolism and disorders.

Ye-Shih Ho has contributed to multiple publications in a variety of scientific venues. Some recent papers include:

  • "Catalase deficiency induces reactive oxygen species mediated pexophagy and cell death in the liver during prolonged fasting," 2021, BioFactors
  • "Catalase-deficient mice induce aging faster through lysosomal dysfunction," 2022, Cell Communication and Signaling
  • "Catalase deficiency facilitates the shuttling of free fatty acid to brown adipose tissue through lipolysis mediated by ROS during sustained fasting," 2021, Cell & Bioscience
  • "Tetrandrine regulates NAADP-mediated calcium signaling through a LIMP-2-dependent and sphingosine-mediated mechanism," 2025, Nature Communications

Frequent co-authors collaborating with Ye-Shih Ho include:

  • Raghbendra Kumar Dutta
  • Yunash Maharjan
  • Joon No Lee
  • Channy Park
  • Raekil Park

These collaborations indicate an ongoing engagement with researchers specialized in related molecular and biomedical fields. The diversity of publication venues, such as BioFactors, Cell Communication and Signaling, Cell & Bioscience, and Nature Communications, reflects the interdisciplinary nature of Ye-Shih Ho's research activities.

Best Publications

  • Mice Deficient in Cellular Glutathione Peroxidase Develop Normally and Show No Increased Sensitivity to Hyperoxia

    Ye-Shih Ho;Jean-Luc Magnenat;Roderick T. Bronson;Jin Cao

  • Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta.

    Niki L. Reynaert;Albert van der Vliet;Amy S. Guala;Toby McGovern

  • Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury.

    Ye Shih Ho;Ye Xiong;Wanchao Ma;Abraham Spector

  • Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice.

    Zhongyi Chen;Chu Chang Chua;Ye-Shih Ho;Ronald C. Hamdy

  • Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice

    Zhongyi Chen;Brian Siu;Ye-Shih Ho;Renaud Vincent

  • Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications

    Xin Gen Lei;Jian Hong Zhu;Wen Hsing Cheng;Yongping Bao

  • Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells.

    Rakesh Rathore;Yun Min Zheng;Chun Feng Niu;Qing Hua Liu

  • Glutathione peroxidase protects mice from viral-induced myocarditis

    M A Beck;R S Esworthy;Y S Ho;F F Chu

  • Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress.

    Renu A. Kowluru;Vibhuti Kowluru;Ye Xiong;Ye Shih Ho

  • Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes

    Robert M. Johnson;Gerard Goyette;Y. Ravindranath;Ye-Shih Ho

  • Transgenic mice overexpressing glutathione peroxidase are resistant to myocardial ischemia reperfusion injury.

    Tetsuya Yoshida;Masazumi Watanabe;Daniel T. Engelman;Richard M. Engelman

  • Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

    Oksana Ivashchenko;Paul P. Van Veldhoven;Chantal Brees;Ye Shih Ho

  • The nature of antioxidant defense mechanisms : a lesson from transgenic studies

    Ye-Shih Ho;Jean-Luc Magnenat;Mary Gargano;Jin Cao

  • Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils.

    Jiro Sakai;Jingyu Li;Jingyu Li;Kulandayan Kulandayan K Subramanian;Subhanjan Mondal

  • Catalase Deficiency Accelerates Diabetic Renal Injury Through Peroxisomal Dysfunction

    Inah Hwang;Jiyoun Lee;Joo Young Huh;Jehyun Park

  • Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury.

    Jeffrey N. Keller;Jeffrey N. Keller;Feng F. Huang;Hong Zhu;Jin Yu;Jin Yu

  • Hmox-1 Constitutes an Adaptive Response to Effect Antioxidant Cardioprotection A Study With Transgenic Mice Heterozygous for Targeted Disruption of the Heme Oxygenase-1 Gene

    Tetsuya Yoshida;Nilanjana Maulik;Ye-Shih Ho;Jawed Alam

  • Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia.

    Ye-Shih Ho;Renaud Vincent;Margaret S. Dey;Jan W. Slot

  • Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury.

    T Yoshida;N Maulik;R M Engelman;Y S Ho

  • Oxidative damage of mitochondrial DNA in diabetes and its protection by manganese superoxide dismutase.

    Sally A. Madsen-Bouterse;Qing Zhong;Ghulam Mohammad;Ye Shih Ho

Frequent Co-Authors

Nilanjana Maulik
Nilanjana Maulik University of Connecticut
Yvonne M. W. Janssen-Heininger
Yvonne M. W. Janssen-Heininger University of Vermont
Aron B. Fisher
Aron B. Fisher University of Pennsylvania
Dipak K. Das
Dipak K. Das University of Connecticut
Yefim Manevich
Yefim Manevich Medical University of South Carolina
Hongbo R. Luo
Hongbo R. Luo Boston Children's Hospital
Charles G. Irvin
Charles G. Irvin University of Vermont
Abraham Spector
Abraham Spector Columbia University
Markus Bachschmid
Markus Bachschmid Boston University
Ralph C. Budd
Ralph C. Budd University of Vermont

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