Abraham Spector

Overview

Best Publications

• Oxidative stress-induced cataract: mechanism of action.

  Abraham Spector

  1262
  Citations

• Hydrogen peroxide and human cataract.

  Abraham Spector;William H. Garner

  710
  Citations

• Development of synthetic compounds with glutathione peroxidase activity

  Stephen R. Wilson;Paul A. Zucker;Ruey Ruey C. Huang;Abraham Spector

  579
  Citations

• Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury.

  Ye Shih Ho;Ye Xiong;Wanchao Ma;Abraham Spector

  537
  Citations

• Selective oxidation of cysteine and methionine in normal and senile cataractous lenses

  Margaret H. Garner;Abraham Spector

  450
  Citations

• The search for a solution to senile cataracts. Proctor lecture.

  A Spector

  389
  Citations

• REVIEW: OXIDATIVE STRESS AND DISEASE

  Abraham Spector

  318
  Citations

• The effect of H2O2 upon thioredoxin-enriched lens epithelial cells.

  A. Spector;Guo-Zai Yan;R.-R. C. Huang;M. J. Mcdermott

  270
  Citations

• The chaperone activity of bovine alpha crystallin. Interaction with other lens crystallins in native and denatured states.

  Keyang Wang;A. Spector

  255
  Citations

• cAMP-dependent phosphorylation of bovine lens alpha-crystallin.

  Abraham Spector;Raul Chiesa;Janet Sredy;William Garner

  239
  Citations

• α-Crystallin. The isolation and characterization of distinct macromolecular fractions

  Abraham Spector;Lu-Ku Li;Robert C. Augusteyn;Arthur Schneider

  236
  Citations

• alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner.

  Keyang Wang;Abraham Spector

  235
  Citations

• Lens epithelial cell apoptosis is an early event in the development of UVB-induced cataract.

  Wan-Cheng Li;Abraham Spector

  230
  Citations

• Disulfide-linked high molecular weight protein associated with human cataract.

  Abraham Spector;Debdutta Roy

  215
  Citations

• Oxygen tension in the rabbit lens and vitreous before and after vitrectomy.

  Irene A Barbazetto;Jianhong Liang;Stanley Chang;Lei Zheng

  197
  Citations

• Identification of beta carbolines isolated from fluorescent human lens proteins.

  James Dillon;Abraham Spector;Koji Nakanishi

  187
  Citations

• Membrane cholesterol and phospholipid in consecutive concentric sections of human lenses

  Lu-Ku Li;Lydia So;Abraham Spector

  180
  Citations

• Alpha-crystallin can act as a chaperone under conditions of oxidative stress.

  Keyang Wang;A. Spector

  162
  Citations

• A brief photochemically induced oxidative insult causes irreversible lens damage and cataract. II. Mechanism of action.

  Abraham Spector;Guo-ming Wang;Ren-Rong Wang;Wan-Cheng Li

  158
  Citations

• What is alpha crystallin

  Abraham Spector;Lu-Ku Li;Dianne Meretsky;Robert Augusteyn

  12
  Citations