D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 11,013 150 World Ranking 6124 National Ranking 2875

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His scientific interests lie mostly in Biochemistry, Crystallin, Lens protein, Oxidative stress and Biophysics. The study incorporates disciplines such as Chromatography and Fluorescence in addition to Biochemistry. His Crystallin research incorporates elements of Disulfide bond, Molecular mass and Serine, Phosphorylation.

His biological study spans a wide range of topics, including Normal values, Beta Carbolines, Cataracts, Chaperone and Normal level. The concepts of his Oxidative stress study are interwoven with issues in Organ culture, Hydroxyl radical, Mechanism of action, Molecular biology and Hydrogen peroxide. His research in Biophysics intersects with topics in Thiol, Lens, Molecular size, Membrane permeability and Fiber cell.

His most cited work include:

  • Oxidative stress-induced cataract: mechanism of action. (735 citations)
  • Hydrogen peroxide and human cataract. (439 citations)
  • Development of synthetic compounds with glutathione peroxidase activity (343 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Biochemistry, Crystallin, Molecular biology, Lens protein and Lens. Abraham Spector focuses mostly in the field of Biochemistry, narrowing it down to topics relating to Biophysics and, in certain cases, Membrane. The Crystallin study combines topics in areas such as Size-exclusion chromatography, Crystallography, Molecular mass, Isoelectric focusing and Phosphorylation.

In his study, Cell biology is inextricably linked to Gene expression, which falls within the broad field of Molecular biology. His Lens protein research includes elements of Chromatography and Fluorescence. His study in Oxidative stress is interdisciplinary in nature, drawing from both Knockout mouse and Hydrogen peroxide.

He most often published in these fields:

  • Biochemistry (52.55%)
  • Crystallin (21.94%)
  • Molecular biology (18.37%)

What were the highlights of his more recent work (between 1999-2016)?

  • Cell biology (10.71%)
  • Molecular biology (18.37%)
  • Catalase (8.16%)

In recent papers he was focusing on the following fields of study:

Cell biology, Molecular biology, Catalase, Oxidative stress and Cell culture are his primary areas of study. His Molecular biology study combines topics in areas such as Gene chip analysis, Real-time polymerase chain reaction, Knockout mouse and Antioxidant. His studies in Catalase integrate themes in fields like Cell, Gene targeting, Transgene and Hydrogen peroxide.

In the subject of general Oxidative stress, his work in Glutathione peroxidase is often linked to Lung disease, thereby combining diverse domains of study. The various areas that Abraham Spector examines in his Cell culture study include Gene expression, DNA damage, Glutathione, Biochemistry and Programmed cell death. His research combines Biophysics and Biochemistry.

Between 1999 and 2016, his most popular works were:

  • Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury. (307 citations)
  • REVIEW: OXIDATIVE STRESS AND DISEASE (185 citations)
  • Oxygen tension in the rabbit lens and vitreous before and after vitrectomy. (121 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

Abraham Spector focuses on Catalase, Molecular biology, Cell culture, Biochemistry and Oxidative stress. In general Catalase study, his work on Glutathione peroxidase often relates to the realm of Population, thereby connecting several areas of interest. His Cell culture study which covers Glutathione that intersects with Programmed cell death, Poly ADP ribose polymerase, DNA damage, Reactive oxygen species and NAD+ kinase.

His study in Enzyme, Crystallin, Heat shock protein, Stress Proteins and Phosphorylation is carried out as part of his Biochemistry studies. His Enzyme study combines topics from a wide range of disciplines, such as Luciferase, HSP60, Chaperone and Lens protein. His Oxidative stress research incorporates themes from Diabetes mellitus, Disease, Pathology and Bioinformatics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Oxidative stress-induced cataract: mechanism of action.

Abraham Spector.
The FASEB Journal (1995)

1156 Citations

Hydrogen peroxide and human cataract.

Abraham Spector;William H. Garner.
Experimental Eye Research (1981)

680 Citations

Development of synthetic compounds with glutathione peroxidase activity

Stephen R. Wilson;Paul A. Zucker;Ruey Ruey C. Huang;Abraham Spector.
Journal of the American Chemical Society (1989)

522 Citations

Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury.

Ye Shih Ho;Ye Xiong;Wanchao Ma;Abraham Spector.
Journal of Biological Chemistry (2004)

471 Citations

Selective oxidation of cysteine and methionine in normal and senile cataractous lenses

Margaret H. Garner;Abraham Spector.
Proceedings of the National Academy of Sciences of the United States of America (1980)

433 Citations

REVIEW: OXIDATIVE STRESS AND DISEASE

Abraham Spector.
Journal of Ocular Pharmacology and Therapeutics (2000)

280 Citations

The effect of H2O2 upon thioredoxin-enriched lens epithelial cells.

A. Spector;Guo-Zai Yan;R.-R. C. Huang;M. J. Mcdermott.
Journal of Biological Chemistry (1988)

261 Citations

The chaperone activity of bovine alpha crystallin. Interaction with other lens crystallins in native and denatured states.

Keyang Wang;A. Spector.
Journal of Biological Chemistry (1994)

245 Citations

α-Crystallin. The isolation and characterization of distinct macromolecular fractions

Abraham Spector;Lu-Ku Li;Robert C. Augusteyn;Arthur Schneider.
Biochemical Journal (1971)

240 Citations

cAMP-dependent phosphorylation of bovine lens alpha-crystallin.

Abraham Spector;Raul Chiesa;Janet Sredy;William Garner.
Proceedings of the National Academy of Sciences of the United States of America (1985)

233 Citations

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