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Biology and Biochemistry

D-Index
83
Citations
22057
World Ranking
3552
National Ranking
1780

Overview

Aron B. Fisher is affiliated with the University of Pennsylvania in the United States and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work intersects with several subfields including Molecular Biology, Pulmonary and Respiratory Medicine, Public Health, Environmental and Occupational Health, Biochemistry, and Immunology.

The scientist's recent research includes studies published in multiple peer-reviewed journals, reflecting a focus on redox biology, oxidative stress, and respiratory health. Notable papers authored or co-authored by Aron B. Fisher include:

  • Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target (2022, Cell Reports)
  • Structural and Functional Diversity of the Peroxiredoxin 6 Enzyme Family (2023, Antioxidants and Redox Signaling)
  • The role of peroxiredoxin 6 in biosynthesis of FAHFAs (2022, Free Radical Biology and Medicine)
  • A Peptide Inhibitor of Peroxiredoxin 6 Phospholipase A2 Activity Significantly Protects against Lung Injury in a Mouse Model of Ventilator Induced Lung Injury (VILI) (2021, Antioxidants)
  • Inhibition of Peroxiredoxin 6 PLA2 Activity Decreases Oxidative Stress and the Severity of Acute Lung Injury in the Mouse Cecal Ligation and Puncture Model (2021, Antioxidants)

Frequent publication venues for Aron B. Fisher's work include:

  • Antioxidants
  • Cell Reports
  • Antioxidants and Redox Signaling
  • Free Radical Biology and Medicine
  • PLoS ONE

The main topics that characterize their research are:

  • Redox biology and oxidative stress
  • Respiratory Support and Mechanisms
  • Neonatal Respiratory Health Research
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Research on Leishmaniasis Studies
  • Glutathione Transferases and Polymorphisms

Aron B. Fisher frequently collaborates with several researchers, including:

  • Chandra Dodia
  • Shampa Chatterjee
  • Sheldon I. Feinstein
  • Matthias Paulus Wagner
  • Pauline Formaglio

Best Publications

  • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis.

    A B Al-Mehdi;K Tozawa;A B Fisher;L Shientag

  • Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen

    Stephen R Thom;Robert L Taber;Ignacio I Mendiguren;James M Clark

  • Endothelial cellular response to altered shear stress

    Aron B. Fisher;Shu Chien;Abdul I. Barakat;Robert M. Nerem

  • Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism.

    Yefim Manevich;Aron B. Fisher

  • Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with πGST

    Y. Manevich;S. I. Feinstein;A. B. Fisher

  • Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities.

    Aron B. Fisher

  • Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase.

    Aron B. Fisher;Chandra Dodia;Yefim Manevich;Jin-Wen Chen

  • Endothelial NADPH Oxidase as the Source of Oxidants in Lungs Exposed to Ischemia or High K

    Abu B. Al-Mehdi;Guochang Zhao;Chandra Dodia;Kasumi Tozawa

  • Redox signaling across cell membranes.

    Aron B. Fisher

  • 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage.

    Yefim Manevich;Tom Sweitzer;Jhang Ho Pak;Sheldon I. Feinstein

  • Reactive species in ischemic rat lung injury: contribution of peroxynitrite

    H. Ischiropoulos;A. B. al-Mehdi;A. B. Fisher

  • Identification of LBM180, a Lamellar Body Limiting Membrane Protein of Alveolar Type II Cells, as the ABC Transporter Protein ABCA3

    Surafel Mulugeta;Joseph M. Gray;Kathleen L. Notarfrancesco;Linda W. Gonzales

  • Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes.

    Luis A. Ralat;Yefim Manevich;and Aron B. Fisher;Roberta F. Colman

  • Superoxide Flux in Endothelial Cells via the Chloride Channel-3 Mediates Intracellular Signaling

    Brian J. Hawkins;Muniswamy Madesh;C. J. Kirkpatrick;Aron B. Fisher

  • Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs.

    Vladimir R. Muzykantov;Melpo Christofidou-Solomidou;Irina Balyasnikova;Irina Balyasnikova;David W. Harshaw

  • Oxygen-dependent lipid peroxidation during lung ischemia.

    A B Fisher;C Dodia;Z T Tan;I Ayene

  • Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling.

    Aron B. Fisher

  • Identification of a Human cDNA Clone for Lysosomal Type Ca2+-independent Phospholipase A2 and Properties of the Expressed Protein *

    Tae Suk Kim;Chennarayapatna S. Sundaresh;Sheldon I. Feinstein;Chandra Dodia

  • Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element

    Ibrul Chowdhury;Yiqun Mo;Ling Gao;Altaf Kazi

  • Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages

    Shampa Chatterjee;Sheldon I. Feinstein;Chandra Dodia;Elena Sorokina

Frequent Co-Authors

Yefim Manevich
Yefim Manevich Medical University of South Carolina
Vladimir R. Muzykantov
Vladimir R. Muzykantov University of Pennsylvania
Henry Jay Forman
Henry Jay Forman University of Southern California
David W. Speicher
David W. Speicher The Wistar Institute
Muniswamy Madesh
Muniswamy Madesh The University of Texas at Austin
Steven M. Albelda
Steven M. Albelda University of Pennsylvania
Ye-Shih Ho
Ye-Shih Ho Wayne State University
Michael F. Beers
Michael F. Beers University of Pennsylvania
Douglas B. Cines
Douglas B. Cines University of Pennsylvania
Harry Ischiropoulos
Harry Ischiropoulos Children's Hospital of Philadelphia

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