Geert J. P. L. Kops mainly focuses on Cell biology, Mitosis, Akt/PKB signaling pathway, FOXO4 and Forkhead Transcription Factors. His Cell biology research is multidisciplinary, incorporating elements of Cell cycle checkpoint, Mad2, Spindle checkpoint, Cell cycle and Kinetochore. His studies in Kinetochore integrate themes in fields like Mitotic exit and Anaphase.
The Mitosis study combines topics in areas such as Chromosome, Chromosome segregation, Aurora B kinase and Kinase activity. The study incorporates disciplines such as Cancer research, Cyclin-dependent kinase 9 and MAP kinase kinase kinase in addition to Akt/PKB signaling pathway. His FOXO4 research includes elements of Retinoblastoma protein and FOXO Family.
Geert J. P. L. Kops mainly investigates Cell biology, Kinetochore, Mitosis, Spindle checkpoint and Chromosome segregation. His Cell biology research is multidisciplinary, relying on both G2-M DNA damage checkpoint, Cell cycle checkpoint, Mad2, Cell cycle and Aurora B kinase. His Kinetochore research integrates issues from Spindle apparatus, Microtubule, Anaphase and Evolutionary biology.
His research in Mitosis intersects with topics in Cell division, Kinase activity, Molecular biology, Mitotic exit and Chromosome instability. Geert J. P. L. Kops interconnects Prometaphase, BUB1, BUB3, Kinase and Computational biology in the investigation of issues within Spindle checkpoint. Geert J. P. L. Kops has included themes like Centromere, Meiosis, Protein kinase domain and Microtubule-associated protein in his Chromosome segregation study.
His main research concerns Kinetochore, Cell biology, Mitosis, Spindle checkpoint and Chromosome segregation. His Kinetochore research includes themes of Spindle apparatus, Cell division, Homologous chromosome and Anaphase. Geert J. P. L. Kops studies Cell biology, focusing on Microtubule in particular.
Geert J. P. L. Kops has researched Mitosis in several fields, including Cancer, Colorectal cancer, Chromosome instability and Cancer research. His Spindle checkpoint study combines topics in areas such as Cell signaling and Mad1. His Chromosome segregation research incorporates elements of Andrology, Multipolar spindles and Aneuploidy.
His primary areas of study are Mitosis, Cancer research, Evolutionary biology, Aneuploidy and Kinetochore. His study on Mitosis is covered under Cell biology. His studies deal with areas such as Cancer, Cetuximab and Chromosome instability as well as Cancer research.
The concepts of his Evolutionary biology study are interwoven with issues in Homologous chromosome, Ubiquitin, Gene and Cell division. His research integrates issues of Chromatin, Centromere, Repeated sequence and Function in his study of Aneuploidy. Geert J. P. L. Kops has researched Kinetochore in several fields, including Cyclin-dependent kinase 1, Cyclin B1 and Homology.
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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1.
René H. Medema;Geert J. P. L. Kops;Johannes L. Bos;Boudewijn M. T. Burgering.
Nature (2000)
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
Geert J. P. L. Kops;Tobias B. Dansen;Paulien E. Polderman;Ingrid Saarloos.
Nature (2002)
On the road to cancer: aneuploidy and the mitotic checkpoint.
Geert J. P. L. Kops;Beth A. A. Weaver;Don W. Cleveland.
Nature Reviews Cancer (2005)
Direct control of the Forkhead transcription factor AFX by protein kinase B
Kops Gj;de Ruiter Nd;De Vries-Smits Am;Powell Dr.
Nature (1999)
Cell cycle and death control: long live Forkheads.
Boudewijn M.T Burgering;Geert J.P.L Kops.
Trends in Biochemical Sciences (2002)
The Forkhead Transcription Factor FoxO Regulates Transcription of p27Kip1 and Bim in Response to IL-2
Marie Stahl;Pascale F. Dijkers;Geert J. P. L. Kops;Susanne M. A. Lens.
Journal of Immunology (2002)
Sequential cancer mutations in cultured human intestinal stem cells
Jarno Drost;Richard H. van Jaarsveld;Bas Ponsioen;Cheryl Zimberlin.
Nature (2015)
Cell Cycle Inhibition by FoxO Forkhead Transcription Factors Involves Downregulation of Cyclin D
Marc Schmidt;Sylvia Fernandez de Mattos;Armando van der Horst;Rob Klompmaker.
Molecular and Cellular Biology (2002)
Control of Cell Cycle Exit and Entry by Protein Kinase B-Regulated Forkhead Transcription Factors
Geert J. P. L. Kops;Rene H. Medema;Janet Glassford;Marieke A. G. Essers.
Molecular and Cellular Biology (2002)
Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations
Aniek Janssen;Marja van der Burg;Karoly Szuhai;Geert J. P. L. Kops.
Science (2011)
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