D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 51 Citations 12,410 110 World Ranking 9397 National Ranking 213

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Anastassis Perrakis focuses on Biochemistry, Model building, Algorithm, Automation and Software. Anastassis Perrakis has included themes like Phase, Set, Bioinformatics and Iterative and incremental development in his Model building study. His Iterative and incremental development research focuses on Macromolecular Substances and how it relates to Structural genomics.

His Algorithm research is multidisciplinary, incorporating elements of Molecular replacement, Macromolecular crystallography and Software suite. Anastassis Perrakis brings together Automation and Nanotechnology to produce work in his papers. Anastassis Perrakis usually deals with Software and limits it to topics linked to Protein Data Bank and Structure, Class and Scripting language.

His most cited work include:

  • Automated protein model building combined with iterative structure refinement. (2302 citations)
  • Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7. (1322 citations)
  • RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. (614 citations)

What are the main themes of his work throughout his whole career to date?

Anastassis Perrakis spends much of his time researching Cell biology, Biochemistry, Protein structure, Crystallography and Stereochemistry. His Cell biology research incorporates elements of Spindle apparatus, DNA replication factor CDT1, Ubiquitin ligase and DNA replication. His work is connected to Autotaxin, Lysophosphatidic acid, DNA, Binding site and Enzyme, as a part of Biochemistry.

His biological study spans a wide range of topics, including Computational biology and Homology. The various areas that he examines in his Crystallography study include Protein Data Bank, Protein Data Bank and Model building. His Protein Data Bank study often links to related topics such as Structure.

He most often published in these fields:

  • Cell biology (22.82%)
  • Biochemistry (21.36%)
  • Protein structure (13.59%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (22.82%)
  • Protein structure (13.59%)
  • Crystallography (13.11%)

In recent papers he was focusing on the following fields of study:

Anastassis Perrakis focuses on Cell biology, Protein structure, Crystallography, Mitosis and Anaphase. His research in Cell biology intersects with topics in Ubiquitin, DNA replication factor CDT1, Endocytosis and DNA replication. His research integrates issues of Computational biology and Homology in his study of Protein structure.

His work in the fields of Crystallography, such as Molecular replacement and Resolution, intersects with other areas such as Surface plasmon resonance. His Anaphase research incorporates themes from Spindle apparatus and Ab initio. His work in Protein Data Bank tackles topics such as Structural bioinformatics which are related to areas like Model building, Structure, Pipeline and Loop modeling.

Between 2017 and 2021, his most popular works were:

  • Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis. (38 citations)
  • Homology-based hydrogen bond information improves crystallographic structures in the PDB. (18 citations)
  • Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP. (14 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Cell biology, Protein structure, Microtubule, Protein Data Bank and Spindle apparatus. Anastassis Perrakis interconnects Phospholipase and Phosphodiesterase in the investigation of issues within Cell biology. His Protein structure research is multidisciplinary, relying on both Glycosylation, Asparagine, Protein folding, Glycan and Computational biology.

The various areas that he examines in his Protein Data Bank study include Metric, Crystallography, Standard score, Outlier and Protein Data Bank. The concepts of his Protein Data Bank study are interwoven with issues in Model building, Structural bioinformatics, Structure, Pipeline and Loop modeling. In his study, Dynein is inextricably linked to Mitosis, which falls within the broad field of Spindle apparatus.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Automated protein model building combined with iterative structure refinement.

Anastassis Perrakis;Richard Morris;Victor S. Lamzin.
Nature Structural & Molecular Biology (1999)

3164 Citations

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7.

Gerrit G Langer;Serge X Cohen;Victor S Lamzin;Anastassis Perrakis.
Nature Protocols (2008)

1616 Citations

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.

Martijn Kedde;Markus J. Strasser;Bijan Boldajipour;Joachim A.F. Oude Vrielink.
Cell (2007)

785 Citations

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch.

Meindert H. Lamers;Anastassis Perrakis;Jacqueline H. Enzlin;Jacqueline H. Enzlin;Herrie H. K. Winterwerp.
Nature (2000)

721 Citations

Developments in the CCP4 molecular-graphics project

Liz Potterton;Stuart Mcnicholas;Eugene Krissinel;Jan Gruber.
Acta Crystallographica Section D-biological Crystallography (2004)

671 Citations

wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models.

A. Perrakis;T.K. Sixma;K.S. Wilson;V.S. Lamzin.
Acta Crystallographica Section D-biological Crystallography (1997)

639 Citations

ARP/wARP and automatic interpretation of protein electron density maps.

Richard J. Morris;Anastassis Perrakis;Victor S. Lamzin.
Methods in Enzymology (2003)

594 Citations

ARP/wARP and molecular replacement

Anastassis Perrakis;Maria Harkiolaki;Keith S. Wilson;Victor S. Lamzin.
Acta Crystallographica Section D-biological Crystallography (2001)

578 Citations

Crystal structure of a bacterial chitinase at 2.3 Å resolution

Anastassis Perrakis;Ivo Tews;Zbigniew Dauter;Amos B Oppenheim.
Structure (1994)

507 Citations

The PDB_REDO server for macromolecular structure model optimization.

Robbie P. Joosten;Fei Long;Garib N. Murshudov;Anastassis Perrakis.
IUCrJ (2014)

495 Citations

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