World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
94
Citations
37792
World Ranking
1981
National Ranking
1078

Research.com Recognitions

  • 2003 - Member of the European Academy of Sciences

Overview

Andrzej Joachimiak is affiliated with Argonne National Laboratory in the United States. Their research spans multiple fields within biochemistry, genetics, and molecular biology, with a strong focus also on medicine. Within these broader fields, they have contributed significantly to subfields such as molecular biology, infectious diseases, materials chemistry, immunology, and pharmacology.

The scientist's work concentrates on topics including RNA and protein synthesis mechanisms, SARS-CoV-2 and COVID-19 research, enzyme structure and function, protein structure and dynamics, biochemical and molecular research, RNA modifications and cancer, and CRISPR and genetic engineering.

Recent publications authored or co-authored by Andrzej Joachimiak include the following:

  • Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography, 2020, Nature Communications
  • Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors, 2021, Nature Communications
  • Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV -2, 2020, Protein Science
  • Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2, 2021, Science
  • Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets, 2021, Immunity

Joachimiak frequently collaborates with several researchers, including:

  • K. Michalska
  • R. Jedrzejczak
  • Youngchang Kim
  • M. Endres
  • N. Maltseva

The scientist has published extensively in notable venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Acta Crystallographica Section A Foundations and Advances, Protein Science, and Research Square. The distribution of publications highlights their interdisciplinary approach and engagement with both preprint and peer-reviewed outlets.

In recognition of their contribution to science, Andrzej Joachimiak became a member of the European Academy of Sciences in 2003.

Best Publications

  • Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

    Jian-Ping Xiong;Thilo Stehle;Rongguang Zhang;Andrzej Joachimiak

  • Crystal Structure of the Extracellular Segment of Integrin αVβ3

    Jian-Ping Xiong;Thilo Stehle;Beate Diefenbach;Rongguang Zhang

  • The crystal structure of the bacterial chaperonin GroEL at 2.8 A.

    Kerstin Braig;Zbyszek Otwinowski;Zbyszek Otwinowski;Rashmi Hegde;Rashmi Hegde;David C. Boisvert

  • A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus

    Joseph D. Mougous;Marianne E. Cuff;Stefan Raunser;Aimee Shen

  • Crystal structure of trp repressor/operator complex at atomic resolution.

    Otwinowski Z;Schevitz Rw;Zhang Rg;Lawson Cl

  • Protein production and purification.

    S Gräslund

  • The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

    Yangrong Cao;Yan Liang;Kiwamu Tanaka;Cuong T Nguyen

  • Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

    Motomu Shimaoka;Tsan Sam Xiao;Jin Huan Liu;Yuting Yang

  • Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA

    Rong-guang Zhang;Terina Pappas;Jennifer L. Brace;Paula C. Miller;Paula C. Miller

  • Structural plasticity of SARS-CoV-2 3CL M pro active site cavity revealed by room temperature X-ray crystallography.

    Daniel W. Kneller;Gwyndalyn Phillips;Hugh M. O’Neill;Robert Jedrzejczak

  • The crystal structure of a T cell receptor in complex with peptide and MHC class II

    Ellis L. Reinherz;Kemin Tan;Lei Tang;Petra Kern

  • Proliferating Cell Nuclear Antigen (PCNA): Ringmaster of the Genome

    T. Paunesku;S. Mittal;M. Protić;J. Oryhon

  • Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.

    Jerzy Osipiuk;Jerzy Osipiuk;Saara Anne Azizi;Steve Dvorkin;Michael Endres;Michael Endres

  • The three-dimensional structure of trp repressor

    Richard W. Schevitz;Zdzislaw Otwinowski;Andrzej Joachimiak;Catherine L. Lawson

  • Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

    Yuequan Shen;Andrzej Joachimiak;Marsha Rich Rosner;Wei-Jen Tang

  • A Family of LIC Vectors for High-Throughput Cloning and Purification of Proteins

    William H. Eschenfeldt;Stols Lucy;Cynthia Sanville Millard;Andrzej Joachimiak

  • Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2.

    Youngchang Kim;Youngchang Kim;Robert Jedrzejczak;Robert Jedrzejczak;Natalia I. Maltseva;Natalia I. Maltseva;Mateusz Wilamowski

  • Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors

    Jerzy Osipiuk;Jerzy Osipiuk;Saara-Anne Azizi;Steve Dvorkin;Michael Endres;Michael Endres

  • Author response: The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

    Yangrong Cao;Yan Liang;Kiwamu Tanaka;Cuong T Nguyen

  • A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein

    Joseph D. Mougous;Marianne E. Cuff;Stefan Raunser;Aimee Shen

Frequent Co-Authors

Youngchang Kim
Youngchang Kim Argonne National Laboratory
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Alexei Savchenko
Alexei Savchenko University of Calgary
Rongguang Zhang
Rongguang Zhang Chinese Academy of Sciences
Alexander F. Yakunin
Alexander F. Yakunin Bangor University
Wayne F. Anderson
Wayne F. Anderson Northwestern University
George N. Phillips
George N. Phillips Rice University
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Wladek Minor
Wladek Minor University of Virginia
Paul B. Sigler
Paul B. Sigler Yale University

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