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Biology and Biochemistry

D-Index
76
Citations
31220
World Ranking
4939
National Ranking
2371

Overview

Antonio Iavarone is affiliated with Columbia University Medical Center in the United States and specializes primarily in research intersecting biochemistry, genetics, molecular biology, and medicine. Their work is prominently related to glioma diagnosis and treatment, with additional focus areas that include ferroptosis and cancer prognosis, immune cells in cancer, single-cell and spatial transcriptomics, cancer genomics and diagnostics, epigenetics and DNA methylation, as well as neuroinflammation and neurodegeneration mechanisms.

Their publication record includes contributions to several leading journals and venues, with frequent publications in Neuro-Oncology, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Cell, and Cancer Cell.

  • Neuro-Oncology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Cancer Cell

Among recent published papers, notable works include:

  • Proteogenomic and metabolomic characterization of human glioblastoma, 2021, Cancer Cell
  • Glioblastoma hijacks neuronal mechanisms for brain invasion, 2022, Cell
  • Glioma progression is shaped by genetic evolution and microenvironment interactions, 2022, Cell
  • Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities, 2021, Nature Cancer
  • Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer, 2020, Cell

Frequent collaborators include Anna Lasorella, Fulvio D'Angelo, Luciano Garofano, Michele Ceccarelli, and Marc Sanson, reflecting a network of sustained scholarly partnerships.

  • Anna Lasorella
  • Fulvio D'Angelo
  • Luciano Garofano
  • Michele Ceccarelli
  • Marc Sanson

Their research spans a broad spectrum of subfields within biochemistry, genetics, and molecular biology, with significant contributions in molecular biology, genetics, cancer research, immunology, and pulmonary and respiratory medicine.

  • Molecular Biology
  • Genetics
  • Cancer Research
  • Immunology
  • Pulmonary and Respiratory Medicine

Best Publications

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • The transcriptional network for mesenchymal transformation of brain tumours

    Maria Stella Carro;Wei Keat Lim;Mariano Javier Alvarez;Robert J. Bollo

  • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.

    I Reynisdóttir;K Polyak;A Iavarone;J Massagué

  • Transforming fusions of FGFR and TACC genes in human glioblastoma

    Devendra Singh;Joseph Minhow Chan;Pietro Zoppoli;Francesco Niola;Francesco Niola

  • Id family of helix-loop-helix proteins in cancer

    Jonathan Perk;Antonio Iavarone;Robert Benezra

  • Clonal evolution of glioblastoma under therapy.

    Jiguang Wang;Emanuela Cazzato;Erik Ladewig;Veronique Frattini

  • Proteogenomic and metabolomic characterization of human glioblastoma

    Liang-Bo Wang;Alla Karpova;Marina A. Gritsenko;Jennifer E. Kyle

  • An anatomic transcriptional atlas of human glioblastoma

    Ralph B. Puchalski;Nameeta Shah;Jeremy Miller;Rachel Dalley

  • Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins

    Anna Lasorella;Michela Noseda;Mercedes Beyna;Yoshifumi Yokota

  • Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

    Dominik Sturm;Sebastian Bender;David T. W. Jones;Peter Lichter

  • The integrated landscape of driver genomic alterations in glioblastoma

    Veronique Frattini;Vladimir Trifonov;Joseph Minhow Chan;Angelica Castano

  • Longitudinal molecular trajectories of diffuse glioma in adults

    Floris P. Barthel;Kevin C. Johnson;Frederick S. Varn;Anzhela D. Moskalik

  • The ID proteins: master regulators of cancer stem cells and tumour aggressiveness

    Anna Lasorella;Robert Benezra;Antonio Iavarone

  • Transcriptional Activation of the Human p21WAF1/CIP1 Gene by Retinoic Acid Receptor CORRELATION WITH RETINOID INDUCTION OF U937 CELL DIFFERENTIATION

    Min Liu;Antonio Iavarone;Leonard P. Freedman

  • Id2 specifically alters regulation of the cell cycle by tumor suppressor proteins.

    A Lasorella;A Iavarone;M A Israel

  • Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth

    Anna Lasorella;Judith Stegmüller;Daniele Guardavaccaro;Guangchao Liu

  • The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein.

    Xudong Zhao;Julian Ik-Tsen Heng;Daniele Guardavaccaro;Richeng Jiang

  • Erratum: Id family of helix-loop-helix proteins in cancer

    Jonathan Perk;Antonio Iavarone;Robert Benezra

Frequent Co-Authors

Raul Rabadan
Raul Rabadan Columbia University
Houtan Noushmehr
Houtan Noushmehr Henry Ford Health System
Do-Hyun Nam
Do-Hyun Nam Samsung Medical Center
Jill S. Barnholtz-Sloan
Jill S. Barnholtz-Sloan Case Western Reserve University
Andrea Califano
Andrea Califano Columbia University
Gaetano Finocchiaro
Gaetano Finocchiaro Istituto Neurologico Carlo Besta
Roel G.W. Verhaak
Roel G.W. Verhaak The Jackson Laboratory
Robert Benezra
Robert Benezra Memorial Sloan Kettering Cancer Center
Maciej Wiznerowicz
Maciej Wiznerowicz Poznan University of Medical Sciences
Rameen Beroukhim
Rameen Beroukhim Harvard University

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