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D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
31548
World Ranking
5800
National Ranking
2743

Overview

Robert Benezra is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily engages the fields of Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. Within these main fields, their focus extends into subfields including Molecular Biology, Immunology, Pharmacology, Pulmonary and Respiratory Medicine, and Genetics.

Their work encompasses a range of topics notably related to cancer biology and immune regulation. These include cancer-related gene regulation, immune cells in cancer, TGF-β signaling in diseases, epigenetics and DNA methylation, inflammatory mediators and NSAID effects, glioma diagnosis and treatment, and phagocytosis and immune regulation.

Among recent publications attributed to collaborators with Benezra's involvement are:

  • The nuclear factor ID3 endows macrophages with a potent anti-tumour activity, 2024, published in Nature
  • Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response, 2020, OncoImmunology
  • Anti-tumor effects of an ID antagonist with no observed acquired resistance, 2021, npj Breast Cancer
  • Anti-tumor effects of an Id antagonist with no acquired resistance, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Withdrawal: Cyclooxygenase-2-derived prostaglandin E2 stimulates Id-1 transcription., 2020, Journal of Biological Chemistry

Frequent coauthors working alongside Benezra include Andrew J. Dannenberg, Joan Massagué, Yvette Chin, Xi Kathy Zhou, and Paulina M. Wojnarowicz.

The venues with the most frequent publications related to Benezra's research include bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature, OncoImmunology, and npj Breast Cancer.

Best Publications

  • The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

    Robert Benezra;Robert L. Davis;Robert L. Davis;Daniel Lockshon;David L. Turner

  • Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

    David Lyden;Koichi Hattori;Koichi Hattori;Sergio Dias;Carla Costa

  • The myoD gene family: nodal point during specification of the muscle cell lineage

    Harold Weintraub;Robert Davis;Stephen Tapscott;Matthew Thayer

  • Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

    David Lyden;Alison Z. Young;David Zagzag;Wei Yan

  • MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

    Loren S. Michel;Vasco Liberal;Anupam Chatterjee;Regina Kirchwegger

  • Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?

    Shahin Rafii;David Lyden;David Lyden;Robert Benezra;Robert Benezra;Koichi Hattori

  • Identification of a Human Mitotic Checkpoint Gene: hsMAD2

    Yong Li;Robert Benezra

  • Tumor entrained neutrophils inhibit seeding in the premetastatic lung

    Zvi Granot;Erik Henke;Elizabeth A. Comen;Tari A. King

  • Id proteins in development, cell cycle and cancer

    Marianna B. Ruzinova;Robert Benezra

  • Mad2 Overexpression Promotes Aneuploidy and Tumorigenesis in Mice

    Rocío Sotillo;Eva Hernando;Elena Díaz-Rodríguez;Julie Teruya-Feldstein

  • Id family of helix-loop-helix proteins in cancer

    Jonathan Perk;Antonio Iavarone;Robert Benezra

  • Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors

    Yuval Shaked;Alessia Ciarrocchi;Marcela Franco;Christina R. Lee

  • Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.

    Yale Jen;Harold Weintraub;Robert Benezra

  • Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control

    Eva Hernando;Zaher Nahlé;Zaher Nahlé;Gloria Juan;Elena Diaz-Rodriguez

  • Chromosome Missegregation and Apoptosis in Mice Lacking the Mitotic Checkpoint Protein Mad2

    Max Dobles;Vasco Liberal;Martin L Scott;Robert Benezra

  • Rapid Chemotherapy-Induced Acute Endothelial Progenitor Cell Mobilization: Implications for Antiangiogenic Drugs as Chemosensitizing Agents

    Yuval Shaked;Erik Henke;Jeanine M.L. Roodhart;Patrizia Mancuso

  • Mitotic chromosomal instability and cancer: mouse modelling of the human disease

    Juan-Manuel Schvartzman;Rocio Sotillo;Robert Benezra

  • Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization

    Daniel J. Nolan;Daniel J. Nolan;Alessia Ciarrocchi;Albert Sleiman Mellick;Jaspreet S. Jaggi

  • The ID proteins: master regulators of cancer stem cells and tumour aggressiveness

    Anna Lasorella;Robert Benezra;Antonio Iavarone

  • Expansion and maintenance of human embryonic stem cell–derived endothelial cells by TGFβ inhibition is Id1 dependent

    Daylon James;Hyung Song Nam;Hyung Song Nam;Marco Seandel;Marco Seandel;Daniel Nolan

Frequent Co-Authors

Larry Norton
Larry Norton Memorial Sloan Kettering Cancer Center
Vivek Mittal
Vivek Mittal Cornell University
Andrew J. Dannenberg
Andrew J. Dannenberg Cornell University
Antonio Iavarone
Antonio Iavarone Columbia University Medical Center
Shahin Rafii
Shahin Rafii Cornell University
David Lyden
David Lyden Cornell University
William L. Gerald
William L. Gerald Memorial Sloan Kettering Cancer Center
Katia Manova
Katia Manova Memorial Sloan Kettering Cancer Center
Joan Massagué
Joan Massagué Memorial Sloan Kettering Cancer Center
Neal Rosen
Neal Rosen Memorial Sloan Kettering Cancer Center

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