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Biology and Biochemistry

D-Index
81
Citations
28850
World Ranking
3823
National Ranking
1893

Overview

James M. Olson is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research primarily focuses on medicine and the intersecting fields of biochemistry, genetics, and molecular biology. Within these broad domains, Olson's work delves into molecular biology, genetics, oncology, immunology, and pulmonary and respiratory medicine.

The scientist has published extensively on topics including glioma diagnosis and treatment, protein degradation and inhibitors, immunotherapy and immune responses, histone deacetylase inhibitors research, CAR-T cell therapy research, immune cell function and interaction, and neuroblastoma research and treatments.

Frequent coauthors in their research collaborations include Emily J. Girard, Sarah Leary, Nicholas A. Vitanza, Fiona Pakiam, and Matthew C. Biery. Olson's publications are often found in journals such as Neuro-Oncology, bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Journal of Neuro-Oncology, and Neuro-Oncology Advances.

Recent papers authored or co-authored by Olson cover various aspects of cancer biology and treatment. These include:

  • Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma, 2021, JAMA Oncology
  • Failure of human rhombic lip differentiation underlies medulloblastoma formation, 2022, Nature
  • Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas, 2022, Neuro-Oncology
  • The transcriptional landscape of Shh medulloblastoma, 2021, Nature Communications
  • Miniproteins as a Powerful Modality in Drug Development, 2020, Trends in Biochemical Sciences

Best Publications

  • Prediction of central nervous system embryonal tumour outcome based on gene expression

    Scott L. Pomeroy;Pablo Tamayo;Michelle Gaasenbeek;Lisa M. Sturla

  • Intertumoral Heterogeneity within Medulloblastoma Subgroups

    Florence M.G. Cavalli;Marc Remke;Marc Remke;Marc Remke;Ladislav Rampasek;John Peacock

  • Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade

    David M. Berman;Sunil S. Karhadkar;Andrew R. Hallahan;Joel I. Pritchard

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • Regional and cellular gene expression changes in human Huntington's disease brain.

    Angela Kaye Hodges;Andrew D. Strand;Aaron K. Aragaki;Alexandre Kuhn

  • Decreased expression of striatal signaling genes in a mouse model of Huntington’s disease

    Ruth Luthi-Carter;Andrew Strand;Nikki L. Peters;Steven M. Solano

  • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.

    Yoon Jae Cho;Aviad Tsherniak;Pablo Tamayo;Sandro Santagata

  • Optical and MRI Multifunctional Nanoprobe for Targeting Gliomas

    Omid Veiseh;Conroy Sun;Jonathan Gunn;Nathan Kohler

  • The SmoA1 Mouse Model Reveals That Notch Signaling Is Critical for the Growth and Survival of Sonic Hedgehog-Induced Medulloblastomas

    Andrew R. Hallahan;Joel I. Pritchard;Stacey Hansen;Mark Benson

  • Generation of neurons by transient expression of neural bHLH proteins in mammalian cells

    Mohamed H. Farah;James M. Olson;Holly B. Sucic;Richard I. Hume

  • Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.

    Mandana Veiseh;Patrik Gabikian;S-Bahram Bahrami;Omid Veiseh

  • Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

    Linda S. Kaltenbach;Eliana Romero;Robert R. Becklin;Rakesh Chettier

  • Accurate de novo design of hyperstable constrained peptides.

    Gaurav Bhardwaj;Vikram Khipple Mulligan;Christopher D. Bahl;Jason M. Gilmore

  • Specific Targeting of Brain Tumors with an Optical/Magnetic Resonance Imaging Nanoprobe across the Blood-Brain Barrier

    Omid Veiseh;Conroy Sun;Chen Fang;Narayan Bhattarai

  • Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites.

    J. T. Greenamyre;J. M. M. Olson;J. B. Penney;A. B. Young

  • Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

    Ruth Luthi-Carter;Sarah A. Hanson;Andrew D. Strand;Donald A. Bergstrom

  • PEI-PEG-Chitosan Copolymer Coated Iron Oxide Nanoparticles for Safe Gene Delivery: synthesis, complexation, and transfection.

    Forrest M. Kievit;Omid Veiseh;Narayan Bhattarai;Chen Fang

  • An Efficient and Robust Statistical Modeling Approach to Discover Differentially Expressed Genes Using Genomic Expression Profiles

    Jeffrey G. Thomas;James M. Olson;Stephen J. Tapscott;Lue Ping Zhao

  • p38 MAP kinase: a convergence point in cancer therapy

    James M. Olson;Andrew R. Hallahan

  • In Vivo MRI Detection of Gliomas by Chlorotoxin‐Conjugated Superparamagnetic Nanoprobes

    Conroy Sun;Omid Veiseh;Jonathan Gunn;Chen Fang

Frequent Co-Authors

Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Stephen J. Tapscott
Stephen J. Tapscott Fred Hutchinson Cancer Research Center
Marcel Kool
Marcel Kool German Cancer Research Center
Roland K. Strong
Roland K. Strong Fred Hutchinson Cancer Research Center
Michael D. Taylor
Michael D. Taylor University of Toronto
Richard G. Ellenbogen
Richard G. Ellenbogen University of Washington
Anne B. Young
Anne B. Young Harvard University
Amar Gajjar
Amar Gajjar St. Jude Children's Research Hospital
Charles Kooperberg
Charles Kooperberg Fred Hutchinson Cancer Research Center
Miqin Zhang
Miqin Zhang University of Washington

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