World's Best Scientists 2026 revealed!

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Medicine

D-Index
96
Citations
30888
World Ranking
9748
National Ranking
5014

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

John P. Kane is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with notable contributions to subfields including Cardiology and Cardiovascular Medicine, Molecular Biology, Genetics, Cancer Research, and Surgery.

The scientist's research topics encompass various aspects of lipid metabolism and cardiovascular health. Key topics covered include:

  • Lipid metabolism and disorders
  • Cancer, Lipids, and Metabolism
  • Lipoproteins and Cardiovascular Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Genetic Associations and Epidemiology
  • Atherosclerosis and Cardiovascular Diseases
  • Metabolism, Diabetes, and Cancer

John P. Kane has contributed to several peer-reviewed articles. Some of the recent papers include:

  • Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial (2021) published in The Lancet Diabetes & Endocrinology
  • Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus (2021) published in Current Opinion in Pharmacology
  • Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis (2023) published in Nature
  • Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry (2023) published in Journal of the American Heart Association
  • Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia (2020) published in Arteriosclerosis Thrombosis and Vascular Biology

The scientist has collaborated frequently with various researchers, including Mary J. Malloy, Clive R. Pullinger, Eveline O. Stock, Gregory M. Marcus, and Irina Movsesyan.

John P. Kane's work has been published in several recurring venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of the American Heart Association, Journal of Clinical Lipidology, UNC Libraries, and the 2021 International Conference on Computational Science and Computational Intelligence (CSCI).

Among distinctions, the scientist is recognized as a Member of the Association of American Physicians.

Best Publications

  • Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens.

    John P. Kane;Mary J. Malloy;Thomas A. Ports;Nancy R. Phillips

  • A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

    Ying Liu;Cynthia Helms;Wilson Liao;Lisa C. Zaba

  • Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons

    John P. Kane;David A. Hardman;Harold E. Paulus

  • Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation

    Carolina Roselli;Mark D. Chaffin;Lu Chen Weng;Lu Chen Weng;Stefanie Aeschbacher

  • Apolipoprotein L-I is the trypanosome lytic factor of human serum

    Luc Vanhamme;Françoise Paturiaux-Hanocq;Philippe Poelvoorde;Derek P. Nolan;Derek P. Nolan

  • Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man.

    Richard J. Havel;John P. Kane;Moti L. Kashyap

  • Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype

    Clive R. Pullinger;Celeste Eng;Gerald Salen;Sarah Shefer

  • Lipopolysaccharide (LPS)-binding Protein Is Carried on Lipoproteins and Acts as a Cofactor in the Neutralization of LPS

    Mark M. Wurfel;Steven T. Kunitake;Henri Lichenstein;John P. Kane

  • Apoprotein composition of very low density lipoproteins of human serum.

    John P. Kane;Teizo Sata;Robert L. Hamilton;Richard J. Havel

  • Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque.

    J H Rapp;A Lespine;R L Hamilton;N Colyvas

  • Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans

    R. J. Havel;J. P. Kane;E. O. Balasse;N. Segel

  • APOLIPOPROTEIN B: STRUCTURAL AND METABOLIC HETEROGENEITY

    John P. Kane

  • Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.

    W J Schneider;P T Kovanen;M S Brown;J L Goldstein

  • Prediction of Coronary Heart Disease Risk using a Genetic Risk Score: The Atherosclerosis Risk in Communities Study

    Alanna C. Morrison;Lance A. Bare;Lloyd E. Chambless;Stephen G. Ellis

  • Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Shenghui Duan

  • Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy.

    Lei Zhang;James Song;Giorgio Cavigiolio;Brian Y. Ishida

  • Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With Sitosterolemia

    G. Salen;K. von Bergmann;D. Lütjohann;P. Kwiterovich

  • Primary Dysbetalipoproteinemia: Predominance of a Specific Apoprotein Species in Triglyceride-Rich Lipoproteins

    Richard J. Havel;John P. Kane

  • Apolipoprotein L-I is the trypanosome lytic factor of human serum, and is blocked by SRA in Trypanosoma rhodesiense. Nature 422:83-87

    L. Vanhamme;F Paturiaux-Hanocq;P Poelvoorde;D.P. Nolan

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    L. C. Tsoi;S. L. Spain;J. Knight;E. Ellinghaus

Frequent Co-Authors

Clive R. Pullinger
Clive R. Pullinger University of California, San Francisco
Richard J. Havel
Richard J. Havel University of California, San Francisco
Bradley E. Aouizerat
Bradley E. Aouizerat New York University
Robert L. Hamilton
Robert L. Hamilton University of California, San Francisco
Pui-Yan Kwok
Pui-Yan Kwok University of California, San Francisco
Stephen G. Ellis
Stephen G. Ellis Cleveland Clinic
Kenneth R. Feingold
Kenneth R. Feingold University of California, San Francisco
Carl Grunfeld
Carl Grunfeld University of California, San Francisco
Daniel J. Rader
Daniel J. Rader University of Pennsylvania
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston

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