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Raphael Scharfmann

Raphael Scharfmann

D-Index & Metrics

Molecular Biology

D-Index
63
Citations
15618
World Ranking
1799
National Ranking
57

Overview

Raphael Scharfmann is affiliated with Université Paris Cité in France and has contributed to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work encompasses several subfields, notably Surgery, Genetics, Endocrinology, Diabetes and Metabolism, Molecular Biology, and Oncology.

The scientist's research primarily focuses on pancreatic function and diabetes, covering topics such as diabetes and associated disorders, diabetes management and research, diabetes treatment and management, metabolism linked with diabetes and cancer, endoplasmic reticulum stress and disease, and pancreatic and hepatic oncology research.

Raphael Scharfmann has published numerous papers in several venues. The five notable recent papers include:

  • A roadmap for the Human Developmental Cell Atlas, 2021, Nature
  • Transcription factors that shape the mammalian pancreas, 2020, Diabetologia
  • Purification of pancreatic endocrine subsets reveals increased iron metabolism in beta cells, 2020, Molecular Metabolism
  • Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice, 2020, Diabetes
  • Regulated expression and function of the GABAB receptor in human pancreatic beta cell line and islets, 2020, Scientific Reports

The scientist frequently publishes in specific journals and platforms, such as:

  • bioRxiv (Cold Spring Harbor Laboratory) with 7 publications
  • Molecular Metabolism with 4 publications
  • Diabetes with 4 publications
  • Diabetologia with 3 publications
  • EBioMedicine with 3 publications

Collaborations form a significant part of Raphael Scharfmann's research. Frequent coauthors include Claire Berthault, Masaya Oshima, Roberto Mallone, Latif Rachdi, and Sylvaine You, with documented collaborations ranging from 7 to 11 joint works.

Best Publications

  • Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus

    Andrey P. Babenko;Michel Polak;Hélène Cavé;Kanetee Busiah

  • Child health, developmental plasticity, and epigenetic programming.

    Z. Hochberg;Robert Feil;M. Constancia;M. Fraga

  • A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

    Philippe Ravassard;Yasmine Hazhouz;Séverine Pechberty;Emilie Bricout-Neveu

  • Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

    Anil Bhushan;Nobuyuki Itoh;Shigeaki Kato;Jean P. Thiery

  • Functional antagonism between c-Jun and MyoD proteins: A direct physical association

    Eyal Bengal;Lynn Ransone;Raphael Scharfmann;V.J. Dwarki

  • Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

    Ignasi Morán;İldem Akerman;Martijn van de Bunt;Martijn van de Bunt;Ruiyu Xie

  • Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

    Tamara J. Nicolson;Elisa A. Bellomo;Nadeeja Wijesekara;Merewyn K. Loder

  • Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants

    Raphael Scharfmann;Jonathan H. Axelrod;Inder M. Verma

  • MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines

    Nadine Baroukh;Magalie A. Ravier;Merewyn K. Loder;Elaine V. Hill

  • Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development.

    F. Miralles;P. Czernichow;R. Scharfmann

  • Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.

    Stéphane Cauchi;David Meyre;Christian Dina;Hélène Choquet

  • Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas

    Francisco Miralles;Paul Czernichow;Keiichi Ozaki;Nobuyuki Itoh

  • Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

    Slobodan Culina;Slobodan Culina;Slobodan Culina;Ana Ines Lalanne;Ana Ines Lalanne;Ana Ines Lalanne;Georgia Afonso;Georgia Afonso;Georgia Afonso;Karen Cerosaletti

  • Histone Deacetylase Inhibitors Modify Pancreatic Cell Fate Determination and Amplify Endocrine Progenitors

    Unknown

  • Expression of Neuronal Traits in Pancreatic Beta Cells IMPLICATION OF NEURON-RESTRICTIVE SILENCING FACTOR/REPRESSOR ELEMENT SILENCING TRANSCRIPTION FACTOR, A NEURON-RESTRICTIVE SILENCER

    Fouad Atouf;Paul Czernichow;Raphael Scharfmann

  • TGF-β Plays a Key Role in Morphogenesis of the Pancreatic Islets of Langerhans by Controlling the Activity of the Matrix Metalloproteinase MMP-2

    Francisco Miralles;Tadej Battelino;Paul Czernichow;Raphael Scharfmann

  • Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

    H. Efsun Arda;Lingyu Li;Jennifer Tsai;Eduardo A. Torre

  • Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors

    Sergio Gonzalez-Duque;Marie Eliane Azoury;Maikel Luis Colli;Georgia Afonso;Georgia Afonso;Georgia Afonso

  • Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.

    Corentin Cras-Méneur;Lynda Elghazi;Paul Czernichow;Raphael Scharfmann

  • Oxygen Tension Regulates Pancreatic β-Cell Differentiation Through Hypoxia-Inducible Factor 1α

    Mylène Heinis;Marie-Thérèse Simon;Karine Ilc;Nathalie M. Mazure

Frequent Co-Authors

Paul Czernichow
Paul Czernichow Grenoble Alpes University
Philippe Ravassard
Philippe Ravassard Université Paris Cité
Philippe Froguel
Philippe Froguel Imperial College London
Hélène Cavé
Hélène Cavé Université Paris Cité
Piero Marchetti
Piero Marchetti University of Pisa
Anna L. Gloyn
Anna L. Gloyn Stanford University
Guy A. Rutter
Guy A. Rutter Imperial College London
François Pattou
François Pattou University of Lille
Arnold Munnich
Arnold Munnich Necker-Enfants Malades Hospital

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