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Biology and Biochemistry

D-Index
68
Citations
16238
World Ranking
7798
National Ranking
144

Overview

Romano Regazzi is affiliated with the University of Lausanne in Switzerland and specializes in research spanning biochemistry, genetics, molecular biology, and medicine. Their publication record includes significant contributions to both molecular biology and endocrinology, with a focus on pancreatic function, diabetes, and RNA biology.

The scientist's research covers several main fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work extends into the following subfields:

  • Molecular Biology
  • Cancer Research
  • Surgery
  • Genetics
  • Endocrinology, Diabetes and Metabolism

Romano Regazzi's main topics of research are:

  • Pancreatic function and diabetes
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Diabetes and associated disorders
  • RNA Research and Splicing
  • Circular RNAs in diseases

The scientist has a number of recent papers that highlight ongoing work, including:

  • "A circular RNA generated from an intron of the insulin gene controls insulin secretion," 2020, Nature Communications
  • "Crosstalk between Macrophages and Pancreatic β-Cells in Islet Development, Homeostasis and Disease," 2021, International Journal of Molecular Sciences
  • "Emerging Classes of Small Non-Coding RNAs With Potential Implications in Diabetes and Associated Metabolic Disorders," 2021, Frontiers in Endocrinology
  • "Circular RNAs as Novel Regulators of β-Cell Functions under Physiological and Pathological Conditions," 2021, International Journal of Molecular Sciences
  • "The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development," 2020, Cellular and Molecular Life Sciences

The venues where Romano Regazzi frequently publishes include:

  • International Journal of Molecular Sciences
  • Scientific Reports
  • Diabetologia
  • Comprehensive Physiology
  • Nature Communications

Frequent collaborators involved in several joint publications with Romano Regazzi are:

  • Claudiane Guay
  • Cécile Jacovetti
  • Flora Brozzi
  • Mustafa Bilal Bayazit
  • Véronique Menoud

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Circulating microRNAs as novel biomarkers for diabetes mellitus

    Claudiane Guay;Romano Regazzi

  • Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion.

    M Prentki;S Vischer;M.C. Glennon;R Regazzi

  • Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing

    N Sekine;V Cirulli;R Regazzi;L J Brown

  • MicroRNA-9 Controls the Expression of Granuphilin/Slp4 and the Secretory Response of Insulin-producing Cells

    Valérie Plaisance;Amar Abderrahmani;Amar Abderrahmani;Véronique Perret-Menoud;Patrick Jacquemin

  • Alterations in microRNA expression contribute to fatty acid-induced pancreatic β-cell dysfunction

    Pascal Lovis;Elodie Roggli;D. Ross Laybutt;Sonia Gattesco

  • Diabetes mellitus, a microRNA-related disease?

    Claudiane Guay;Elodie Roggli;Valeria Nesca;Cécile Jacovetti

  • Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic β-cells

    Elodie Roggli;Aurore Britan;Sonia Gattesco;Nathalie Lin-Marq

  • Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs.

    Pascal Lovis;Sonia Gattesco;Romano Regazzi

  • SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

    Karin Sadoul;Jochen Lang;C. Montecucco;U. Weller

  • Changes in MicroRNA Expression Contribute to Pancreatic β-Cell Dysfunction in Prediabetic NOD Mice

    Elodie Roggli;Sonia Gattesco;Dorothée Caille;Claire Briet

  • Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes.

    Valeria Nesca;Claudiane Guay;Cécile Jacovetti;Véronique Menoud

  • Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

    Claudiane Guay;Janine K. Kruit;Sophie Rome;Véronique Menoud

  • VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion.

    R. Regazzi;C. B. Wollheim;Jochen Lang;J.-M. Theler

  • Direct Interaction of the Rab3 Effector RIM with Ca2+Channels, SNAP-25, and Synaptotagmin *

    Thierry Coppola;Sarah Magnin-Lüthi;Véronique Perret-Menoud;Sonia Gattesco

  • The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins.

    R Regazzi;A Kikuchi;Y Takai;C B Wollheim

  • Exosomes as new players in metabolic organ cross-talk.

    Claudiane Guay;Romano Regazzi

  • Exendin-4 Protects β-Cells From Interleukin-1β–Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway

    Mourad Ferdaoussi;Saida Abdelli;Jiang-Yan Yang;Marion Cornu

  • Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells.

    A. Abderrahmani;G. Niederhauser;D. Favre;S. Abdelli

  • Superficial and deep changes of cellular mechanical properties following cytoskeleton disassembly.

    S. Kasas;S. Kasas;X. Wang;H. Hirling;R. Marsault

Frequent Co-Authors

Claes B. Wollheim
Claes B. Wollheim University of Geneva
Gérard Waeber
Gérard Waeber University of Lausanne
Doriano Fabbro
Doriano Fabbro Novartis (Switzerland)
Christian Widmann
Christian Widmann University of Lausanne
Paolo Meda
Paolo Meda University of Geneva
Philippe A. Halban
Philippe A. Halban University of Geneva
Marc Prentki
Marc Prentki University of Montreal
Bernard Thorens
Bernard Thorens University of Lausanne
Mitsunori Fukuda
Mitsunori Fukuda Tohoku University
Christian Boitard
Christian Boitard Université Paris Cité

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