Christian Widmann

Overview

Best Publications

• Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

  Christian Widmann;Spencer Gibson;Matthew B. Jarpe;Gary L. Johnson

  3675
  Citations

• Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor.

  Bernard Thorens;Andrée Porret;Léo Bühler;Shao-Ping Deng

  726
  Citations

• The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases

  Michael H Cardone;Guy S Salvesen;Christian Widmann;Gary Johnson

  667
  Citations

• Caspase-dependent Cleavage of Signaling Proteins during Apoptosis: A TURN-OFF MECHANISM FOR ANTI-APOPTOTIC SIGNALS

  Christian Widmann;Spencer Gibson;Gary L. Johnson

  629
  Citations

• T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.

  J L Casanova;P Romero;C Widmann;P Kourilsky

  462
  Citations

• MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

  Gary R Fanger;Pär Gerwins;Christian Widmann;Matthew B Jarpe

  456
  Citations

• Alterations in microRNA expression contribute to fatty acid-induced pancreatic β-cell dysfunction

  Pascal Lovis;Elodie Roggli;D. Ross Laybutt;Sonia Gattesco

  402
  Citations

• MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis.

  Christian Widmann;Pär Gerwins;Nancy Lassignal Johnson;Matthew B. Jarpe

  311
  Citations

• MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

  Toshiaki Yujiri;Margaret Ware;Margaret Ware;Christian Widmann;Christian Widmann;Ryan Oyer

  309
  Citations

• Reovirus-induced apoptosis is mediated by TRAIL.

  Penny Clarke;Suzanne M. Meintzer;Spencer Gibson;Christian Widmann

  272
  Citations

• Glucose metabolism in cancer cells.

  Alessandro Annibaldi;Christian Widmann

  251
  Citations

• The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes.

  Gérard Waeber;Jérôme Delplanque;Christophe Bonny;Vincent Mooser

  239
  Citations

• Anti-apoptotic versus pro-apoptotic signal transduction: Checkpoints and stop signs along the road to death

  Matthew B Jarpe;Christian Widmann;Cindy Knall;Thomas K Schlesinger

  226
  Citations

• 14-3-3 proteins interact with specific MEK kinases.

  Gary R. Fanger;Christian Widmann;Amy C. Porter;Sue Sather

  209
  Citations

• Exendin-4 Protects β-Cells From Interleukin-1β–Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway

  Mourad Ferdaoussi;Saida Abdelli;Jiang-Yan Yang;Marion Cornu

  193
  Citations

• Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells.

  A. Abderrahmani;G. Niederhauser;D. Favre;S. Abdelli

  193
  Citations

• Delineation of several DR-restricted tetanus toxin T cell epitopes.

  Stephane Demotz;Antonio Lanzavecchia;Ulrich Eisel;Heiner Niemann

  179
  Citations

• Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas

  C Widmann;W Dolci;B Thorens

  164
  Citations

• Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

  Marion Cornu;Jiang-Yan Yang;Evrim Jaccard;Carine Poussin

  158
  Citations

• T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides

  Christian Widmann;Pedro Romero;Janet L. Maryanski;Giampietro Corradin

  155
  Citations