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D-Index & Metrics

Biology and Biochemistry

D-Index
120
Citations
56948
World Ranking
632
National Ranking
403

Overview

Gary L. Johnson is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple disciplines, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology. The subfields they contribute to include Molecular Biology, Oncology, Neurology, Cancer Research, and Organic Chemistry.

Their recent scholarly contributions reflect a variety of research interests and publications in prominent scientific journals. Notable papers include:

  • FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease, 2020, Journal of Clinical Investigation
  • Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial, 2021, Nature Medicine
  • New strategies for targeting kinase networks in cancer, 2021, Journal of Biological Chemistry
  • Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK, 2021, PLoS ONE
  • Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy, 2020, JCI Insight

Their collaborative work involves frequent co-authorship with several researchers, including Michael P. East, Steven P. Angus, Christopher R. M. Asquith, Timothy J. Stuhlmiller, and Shawn M. Gomez.

Gary L. Johnson's publications are predominantly found in venues such as UNC Libraries, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Neuro-Oncology, and the Journal of Biological Chemistry.

The main topics investigated in their work cover a range of biomedical concerns, including:

  • Melanoma and MAPK Pathways
  • Neurofibromatosis and Schwannoma Cases
  • Cancer Genomics and Diagnostics
  • Protein Degradation and Inhibitors
  • Phagocytosis and Immune Regulation
  • Neuroblastoma Research and Treatments
  • Cancer Mechanisms and Therapy

Best Publications

  • Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

    Gary L. Johnson;Razvan Lapadat

  • Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

    Christian Widmann;Spencer Gibson;Matthew B. Jarpe;Gary L. Johnson

  • Organization and regulation of mitogen-activated protein kinase signaling pathways

    Timothy P Garrington;Gary L Johnson

  • Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

    Audrey Minden;Anning Lin;Martin McMahon;Carol Lange-Carter

  • A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

    Carol A. Lange-Carter;Chris M. Pleiman;Anne M. Gardner;Kendall J. Blumer

  • Coordination of Rho GTPase activities during cell protrusion

    Matthias Machacek;Matthias Machacek;Louis Hodgson;Louis Hodgson;Christopher Welch;Hunter Elliott

  • Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

    Anning Lin;Audrey Minden;Horacio Martinetto;Francois Xavier Claret

  • Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

    James S. Duncan;Martin C. Whittle;Kazuhiro Nakamura;Amy N. Abell

  • Mixed-lineage kinase control of JNK and p38 MAPK pathways.

    Kathleen A. Gallo;Gary L. Johnson

  • The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases

    Michael H Cardone;Guy S Salvesen;Christian Widmann;Gary Johnson

  • The c-jun kinase/stress-activated pathway : Regulation, function and role in human disease

    Gary L. Johnson;Kazuhiro Nakamura

  • Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.

    Raphael A. Nemenoff;Sim Winitz;Nan Xin Qian;Vicki Van Putten

  • Caspase-dependent Cleavage of Signaling Proteins during Apoptosis: A TURN-OFF MECHANISM FOR ANTI-APOPTOTIC SIGNALS

    Christian Widmann;Spencer Gibson;Gary L. Johnson

  • Diversity in function and regulation of MAP kinase pathways

    Kendall J. Blumer;Gary L. Johnson

  • Gα12 and Gα13 Stimulate Rho-dependent Stress Fiber Formation and Focal Adhesion Assembly

    Anne Mette Buhl;Nancy Lassignal Johnson;N. Dhanasekaran;Gary L. Johnson

  • Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

    Daniel R. Ambruso;Cindy Knall;Amy N. Abell;Julie Panepinto

  • Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death.

    Nancy Lassignal Johnson;Anne M. Gardner;Katrina M. Diener;Carol A. Lange-Carter

  • Ras-Dependent Growth Factor Regulation of MEK Kinase in PC12 Cells

    Carole A. Lange-Carter;Gary L. Johnson;Gary L. Johnson

  • MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

    Gary R Fanger;Pär Gerwins;Christian Widmann;Matthew B Jarpe

  • Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.

    B E Wadzinski;W H Wheat;S Jaspers;L F Peruski

Frequent Co-Authors

Lynn E. Heasley
Lynn E. Heasley University of Colorado Anschutz Medical Campus
Christian Widmann
Christian Widmann University of Lausanne
Erwin W. Gelfand
Erwin W. Gelfand University of Colorado Anschutz Medical Campus
Spencer B. Gibson
Spencer B. Gibson University of Manitoba
Naohiro Terada
Naohiro Terada University of Florida
David W. H. Riches
David W. H. Riches University of Colorado Denver
Kenneth L. Tyler
Kenneth L. Tyler University of Colorado Denver
Jerry A. Nick
Jerry A. Nick National Jewish Health
Peter M. Henson
Peter M. Henson National Jewish Health
Edward D. Chan
Edward D. Chan National Jewish Health

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