Lee M. Graves

Overview

Best Publications

• Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

  James S. Duncan;Martin C. Whittle;Kazuhiro Nakamura;Amy N. Abell

  850
  Citations

• Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation.

  Karin E. Bornfeldt;Elaine W. Raines;Toru Nakano;Lee M. Graves

  594
  Citations

• Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

  Lee M. Graves;Karin E. Bornfeldt;Elaine W. Raines;Brian C. Potts

  570
  Citations

• Activation of a Novel Calcium-dependent Protein-tyrosine Kinase CORRELATION WITH c-Jun N-TERMINAL KINASE BUT NOT MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION

  Hong Yu;Xiong Li;Gail S. Marchetto;Ruth Dy

  344
  Citations

• Activation of MAPKs in human bronchial epithelial cells exposed to metals

  James M. Samet;Lee M. Graves;Jacqueline Quay;Lisa A. Dailey

  337
  Citations

• Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.

  K E Bornfeldt;L M Graves;E W Raines;Y Igarashi

  324
  Citations

• Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains

  Timothy J. Stuhlmiller;Samantha M. Miller;Jon S. Zawistowski;Kazuhiro Nakamura

  312
  Citations

• Regulation of carbamoyl phosphate synthetase by MAP kinase.

  Lee M. Graves;Hedeel I. Guy;Piotr Kozlowski;Min Huang

  295
  Citations

• Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation.

  Karin E. Bornfeldt;Elaine W. Raines;Lee M. Graves;Michael P. Skinner

  290
  Citations

• cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells.

  Lee M. Graves;Karin E. Bornfeldt;Gretchen M. Argast;Edwin G. Krebs

  261
  Citations

• Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome

  Arunava Ghosh;Raymond C. Coakley;Teresa Mascenik;Temperance R. Rowell

  260
  Citations

• Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases.

  Rony Seger;Dalia Seger;Fred J. Lozeman;Natalie G. Ahn

  239
  Citations

• Activation of the EGF receptor signaling pathway in human airway epithelial cells exposed to metals

  Weidong Wu;Lee M. Graves;Ilona Jaspers;Robert B. Devlin

  224
  Citations

• Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor on Tyrosine 845 Is Required for Zinc-induced Ras Activation *

  Weidong Wu;Lee M. Graves;Gordon N. Gill;Sarah J. Parsons

  187
  Citations

• Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G–protein coupled receptor–EGF receptor transactivation pathway

  Xiong Li;June Weon Lee;Lee M. Graves;H.Shelton Earp

  185
  Citations

• The MAP kinase cascade.

  Jean S. Campbell;Rony Seger;Jonathan D. Graves;Lee M. Graves

  180
  Citations

• MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression

  Gary L Johnson;Henrik G Dohlman;Lee M Graves

  170
  Citations

• Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues

  Paul R. Graves;Lucas J. Aponte-Collazo;Emily M. J. Fennell;Adam C. Graves

  168
  Citations

• Regulation of a Calcium-dependent Tyrosine Kinase in Vascular Smooth Muscle Cells by Angiotensin II and Platelet-derived Growth Factor DEPENDENCE ON CALCIUM AND THE ACTIN CYTOSKELETON

  Amy E. Brinson;Timothy Harding;Pamela A. Diliberto;Yaqin He

  167
  Citations

• Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex

  Jon S. Zawistowski;Samantha M. Bevill;Daniel R. Goulet;Timothy J. Stuhlmiller

  156
  Citations