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Huub Schellekens

Huub Schellekens

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
18612
World Ranking
6299
National Ranking
162

Overview

Huub Schellekens is affiliated with Utrecht University in the Netherlands. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions across related subfields including Computational Theory and Mathematics, Pharmacology, Molecular Biology, Endocrinology, and Food Science.

The main topics addressed in Schellekens's work include Computational Drug Discovery Methods, Enterobacteriaceae and Cronobacter Research, Probiotics and Fermented Foods, Animal Testing and Alternatives, Pharmacogenetics and Drug Metabolism, Biosimilars and Bioanalytical Methods, as well as Pharmaceutical Studies and Practices.

Schellekens has coauthored several papers with frequent collaborators such as Guilherme S. Ferreira, Wouter Boon, Ellen H.M. Moors, Francesco Scaglione, and Paola Minghetti. These partnerships have contributed to multiple publications in well-known scientific venues.

The scientist's recent publications include:

  • "Comparison of drug efficacy in two animal models of type 2 diabetes: A systematic review and meta-analysis," 2020, European Journal of Pharmacology
  • "Pathways in the Drug Development for Alzheimer's Disease (1906-2016): A Bibliometric Study," 2020, Journal of Scientometric Research
  • "Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs," 2023, Translational Psychiatry
  • "Nature of the Interaction of Alpha-D-Mannose and Escherichia coli Bacteria, and Implications for its Regulatory Classification. A Delphi Panel European Consensus Based on Chemistry and Legal Evidence," 2023, Therapeutic Innovation & Regulatory Science
  • "The devolution of biosimilars regulations," 2024, Nature Biotechnology

Publication venues where Schellekens has contributed multiple works include Preprints.org, Journal of Scientometric Research, Translational Psychiatry, European Journal of Pharmacology, and Therapeutic Innovation & Regulatory Science.

Best Publications

  • γ Interferon, CD8 + T cells and antibodies required for immunity to malaria sporozoites

    Louis Schofield;Jaime Villaquiran;Arturo Ferreira;Huub Schellekens

  • THE HEPATITIS DELTA (DELTA) VIRUS POSSESSES A CIRCULAR RNA

    A. Kos;R. Dijkema;A. C. Arnberg;P. H. van der Meide

  • Structure-immunogenicity relationships of therapeutic proteins.

    Suzanne Hermeling;Daan J. A. Crommelin;Huub Schellekens;Wim Jiskoot

  • Immunogenicity of therapeutic proteins: clinical implications and future prospects.

    Huub Schellekens

  • Bioequivalence and the immunogenicity of biopharmaceuticals

    Huub Schellekens

  • Factors influencing the immunogenicity of therapeutic proteins

    Huub Schellekens

  • The Immunogenicity of Polyethylene Glycol: Facts and Fiction

    Huub Schellekens;Wim E. Hennink;Vera Brinks

  • Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon

    A Ferreira;L Schofield;V Enea;H Schellekens

  • Safety-Related Regulatory Actions for Biologicals Approved in the United States and the European Union

    Thijs J. Giezen;Aukje K. Mantel-Teeuwisse;Sabine M. J. M. Straus;Huub Schellekens

  • 9-(2-Phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys.

    Balzarini J;Naesens L;Slachmuylders J;Niphuis H

  • Cloning and expression of the chromosomal immune interferon gene of the rat.

    R. Dijkema;P.H. van der Meide;P.H. Pouwels;M. Caspers

  • Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics.

    Johan J F Verhoef;John F Carpenter;Thomas J Anchordoquy;Huub Schellekens

  • The Purification and Characterization of Rat Gamma Interferon by Use of Two Monoclonal Antibodies

    P H van der Meide;M Dubbeld;K Vijverberg;T Kos

  • Immunological mechanism underlying the immune response to recombinant human protein therapeutics.

    Melody Sauerborn;Vera Brinks;Wim Jiskoot;Huub Schellekens

  • Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis

    Chris H. Polman;Antonio Bertolotto;Florian Deisenhammer;Gavin Giovannoni

  • Antibody response to aggregated human interferon alpha2b in wild-type and transgenic immune tolerant mice depends on type and level of aggregation.

    Suzanne Hermeling;Huub Schellekens;Coen Maas;Martijn F.B.G. Gebbink

  • Biosimilar therapeutics--what do we need to consider?

    Huub Schellekens

  • γ‐interferon treatment inhibits collagen deposition in murine schistosomiasis

    M. J. Czaja;F. R. Weiner;S. Takahashi;M. A. Giambrone

  • Immunogenicity of biopharmaceuticals

    Michele Kessler;David Goldsmith;Huub Schellekens

  • The immunogenicity of biopharmaceuticals.

    Huub Schellekens

Frequent Co-Authors

Wim Jiskoot
Wim Jiskoot Leiden University
Hubert G. M. Leufkens
Hubert G. M. Leufkens Utrecht University
Daan J.A. Crommelin
Daan J.A. Crommelin Utrecht University
Marko P. Hekkert
Marko P. Hekkert Utrecht University
Marc A. Koopmanschap
Marc A. Koopmanschap Erasmus University Rotterdam
Gavin Giovannoni
Gavin Giovannoni Queen Mary University of London
Hans-Peter Hartung
Hans-Peter Hartung Heinrich Heine University Düsseldorf
Wim E. Hennink
Wim E. Hennink Utrecht University
Bernhard Hemmer
Bernhard Hemmer Technical University of Munich
Geert Maertens
Geert Maertens Biocartis (Belgium)

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