World's Best Scientists 2026 revealed!
C. Russell Middaugh

C. Russell Middaugh

D-Index & Metrics

Chemistry

D-Index
74
Citations
18755
World Ranking
4722
National Ranking
1487

C. Russell Middaugh publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where C. Russell Middaugh sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 376 publications — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

C. Russell Middaugh D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where C. Russell Middaugh sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 74 D-Index — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

C. Russell Middaugh is affiliated with the University of Kansas in the United States and has contributed extensively to research in the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Their work spans various subfields including Molecular Biology, Immunology, Epidemiology, Infectious Diseases, and Biomedical Engineering.

The scientist's research addresses core topics such as protein purification and stability, viral infectious diseases and gene expression in insects, protein structure and dynamics, RNA interference and gene delivery, immune response and inflammation, immunotherapy and immune responses, as well as monoclonal and polyclonal antibodies research.

Notable recent papers authored or co-authored by C. Russell Middaugh include:

  • pH-Dependent Phase Behavior and Stability of Cationic Lipid-mRNA Nanoparticles, 2021, Journal of Pharmaceutical Sciences
  • Optimization of RG1-VLP Vaccine Performance in Mice with Novel TLR4 Agonists, 2020, Vaccine
  • Prediction Machines: Applied Machine Learning for Therapeutic Protein Design and Development, 2020, Journal of Pharmaceutical Sciences
  • Short-term and Longer-term Protective Immune Responses Generated by Subunit Vaccination with Smallpox A33, B5, L1 or A27 Proteins Adjuvanted with Aluminum Hydroxide and CpG in Mice Challenged with Vaccinia Virus, 2020, Vaccine
  • Physicochemical Characterization of Biological and Synthetic Forms of Two Lipid A-based TLR4 Agonists, 2023, Heliyon

C. Russell Middaugh has frequently published in a few key venues including the Journal of Pharmaceutical Sciences, Vaccine, Biomolecules, Heliyon, and Frontiers in Immunology.

Throughout their career, Middaugh has collaborated with multiple researchers, often working alongside:

  • Nicholas R. Larson
  • Yangjie Wei
  • Gang Hu
  • Akshay Jain
  • Krzysztof Kuczera

Best Publications

  • Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality

    John F. Carpenter;Theodore W. Randolph;Wim Jiskoot;Daan J.A. Crommelin

  • Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins

    H Mach;C R Middaugh;R V Lewis

  • Protein–excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development

    Tim J. Kamerzell;Reza Esfandiary;Sangeeta B. Joshi;C. Russell Middaugh

  • Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies.

    Ozan S. Kumru;Sangeeta B. Joshi;Dawn E. Smith;C. Russell Middaugh

  • Silicone oil induced aggregation of proteins

    LaToya S. Jones;Allyn Kaufmann;C.Russell Middaugh

  • Biophysical characterization of PEI/DNA complexes.

    Sirirat Choosakoonkriang;Brian A. Lobo;Gary S. Koe;Janet G. Koe

  • Structure/Function Relationships of Polyamidoamine/DNA Dendrimers as Gene Delivery Vehicles

    Chad S. Braun;Joseph A. Vetro;Donald A. Tomalia;Gary S. Koe

  • Conformational Stability and Disassembly of Norwalk Virus-like Particles EFFECT OF pH AND TEMPERATURE

    Salvador F. Ausar;Thomas R. Foubert;Mary H. Hudson;Thomas S. Vedvick

  • Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release

    Wim Jiskoot;Theodore W. Randolph;David B. Volkin;C. Russell Middaugh

  • Nature of the interaction of heparin with acidic fibroblast growth factor

    Henryk Mach;David B. Volkin;Carl J. Burke;C. Russell Middaugh

  • Thermal Stability of Vaccines

    Duane T. Brandau;Latoya S. Jones;Christopher M. Wiethoff;Jason Rexroad

  • Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products

    John F. Carpenter;Theodore W. Randolph;Wim Jiskoot;Daan J.A. Crommelin

  • Effects of adsorption to aluminum salt adjuvants on the structure and stability of model protein antigens.

    LaToya S. Jones;Laura J. Peek;Jonathan Power;Aaron Markham

  • Analysis of plasmid DNA from a pharmaceutical perspective

    C. Russell Middaugh;Robert K. Evans;Donna L. Montgomery;Danilo R. Casimiro

  • Insulin containing polyethylenimine-dextran sulfate nanoparticles

    Waree Tiyaboonchai;James Woiszwillo;Robert C Sims;C.Russell Middaugh

  • The Structure of DNA within Cationic Lipid/DNA Complexes

    Chad S. Braun;Gouri S. Jas;Sirirat Choosakoonkriang;Gary S. Koe

  • Highly concentrated monoclonal antibody solutions: direct analysis of physical structure and thermal stability.

    Unknown

  • Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase.

    Unknown

  • High-Throughput Biophysical Analysis of Protein Therapeutics to Examine Interrelationships Between Aggregate Formation and Conformational Stability

    Rajoshi Chaudhuri;Rajoshi Chaudhuri;Yuan Cheng;C. Russell Middaugh;David B. Volkin

  • Investigation of protein/carbohydrate interactions in the dried state. 2. Diffuse reflectance FTIR studies

    Pierre O Souillac;C.Russell Middaugh;J.Howard Rytting

  • Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations.

    Fei Tian;C. Russell Middaugh;Tom Offerdahl;Eric Munson

  • Derivative Absorbance Spectroscopy and Protein Phase Diagrams as Tools for Comprehensive Protein Characterization: A bGCSF Case Study

    Lisa A. Kueltzo;Baran Ersoy;John P. Ralston;C.Russell. Middaugh

  • The potential role of proteoglycans in cationic lipid-mediated gene delivery. Studies of the interaction of cationic lipid-DNA complexes with model glycosaminoglycans.

    Christopher M. Wiethoff;Janet G. Smith;Gary S. Koe;C. Russell Middaugh

Frequent Co-Authors

David B. Volkin
David B. Volkin University of Kansas
Nicholas J. Mantis
Nicholas J. Mantis New York State Department of Health
Christian Schöneich
Christian Schöneich University of Kansas
Ronald T. Borchardt
Ronald T. Borchardt University of Kansas
Randolph V. Lewis
Randolph V. Lewis Utah State University
Gerhard Winter
Gerhard Winter Ludwig-Maximilians-Universität München
Richard L. Schowen
Richard L. Schowen University of Kansas
Michael Blaber
Michael Blaber Florida State University
John F. Carpenter
John F. Carpenter University of Colorado Anschutz Medical Campus
Theodore W. Randolph
Theodore W. Randolph University of Colorado Boulder

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