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Biology and Biochemistry

D-Index
43
Citations
8255
World Ranking
19381
National Ranking
7911

Overview

Nicholas J. Mantis is affiliated with the New York State Department of Health in the United States. Their research spans multiple disciplines including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

Their work frequently addresses subfields such as Infectious Diseases, Immunology, Biotechnology, Parasitology, and Endocrinology. Key topics within their research portfolio include Toxin Mechanisms and Immunotoxins, SARS-CoV-2 and COVID-19 Research, Transgenic Plants and Applications, Vector-borne Infectious Diseases, Escherichia coli Research Studies, Viral Infections and Vectors, and Viral Gastroenteritis Research and Epidemiology.

Among the notable recent publications by Nicholas J. Mantis are:

  • Gut microbiome and breast-feeding: Implications for early immune development (2022, Journal of Allergy and Clinical Immunology)
  • Serological analysis reveals an imbalanced IgG subclass composition associated with COVID-19 disease severity (2021, Cell Reports Medicine)
  • Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis (2021, Nature Microbiology)
  • Inhibition of invasive salmonella by orally administered IgA and IgG monoclonal antibodies (2020, PLoS Neglected Tropical Diseases)
  • Recombinant Human Secretory IgA Induces Salmonella Typhimurium Agglutination and Limits Bacterial Invasion into Gut-Associated Lymphoid Tissues (2021, ACS Infectious Diseases)

Nicholas J. Mantis has collaborated frequently with several coauthors including David J. Vance, M. Rudolph, Jennifer Doering, Greta Van Slyke, and Graham G. Willsey.

Their scientific findings are published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Infection and Immunity, Human Vaccines & Immunotherapeutics, Methods in Molecular Biology, and Open Forum Infectious Diseases.

Best Publications

  • Secretory IgA's Complex Roles in Immunity and Mucosal Homeostasis in the Gut

    Nicholas J. Mantis;Nicolas Rol;Blaise Corthésy

  • Collaboration of epithelial cells with organized mucosal lymphoid tissues

    Marian R. Neutra;Nicholas J. Mantis;Jean-Pierre Kraehenbuhl

  • Selective Adherence of IgA to Murine Peyer’s Patch M Cells: Evidence for a Novel IgA Receptor

    Nicholas J. Mantis;Marsha C. Cheung;Koteswara R. Chintalacharuvu;Jacques Rey

  • Secretory IgA: Arresting Microbial Pathogens at Epithelial Borders

    Nicholas J. Mantis;Stephen J. Forbes

  • Biological Activities of IgA

    Michael W. Russell;Mogens Kilian;Nicholas J. Mantis;Blaise Corthésy

  • The composition and function of M cell apical membranes: implications for microbial pathogenesis.

    Marian R. Neutra;Nicholas J. Mantis;Andreas Frey;Paul J. Giannasca

  • The Viral σ1 Protein and Glycoconjugates Containing α2-3-Linked Sialic Acid Are Involved in Type 1 Reovirus Adherence to M Cell Apical Surfaces

    Anna Helander;Katherine J. Silvey;Nicholas J. Mantis;Amy B. Hutchings

  • The chromosomal response regulatory gene chvI of Agrobacterium tumefaciens complements an Escherichia coli phoB mutation and is required for virulence.

    N J Mantis;S C Winans

  • Inhibition of Salmonella enterica Serovar Typhimurium Motility and Entry into Epithelial Cells by a Protective Antilipopolysaccharide Monoclonal Immunoglobulin A Antibody

    Stephen J. Forbes;Marisa Eschmann;Nicholas J. Mantis;Nicholas J. Mantis

  • Vaccines against the category B toxins: Staphylococcal enterotoxin B, epsilon toxin and ricin.

    Nicholas J. Mantis

  • Analysis of epithelial cell stress response during infection by Shigella flexneri.

    N Mantis;M C Prévost;P Sansonetti

  • The Agrobacterium tumefaciens vir gene transcriptional activator virG is transcriptionally induced by acid pH and other stress stimuli.

    N J Mantis;S C Winans

  • A Monoclonal Immunoglobulin G Antibody Directed against an Immunodominant Linear Epitope on the Ricin A Chain Confers Systemic and Mucosal Immunity to Ricin

    Lori M. Neal;Joanne O'Hara;Robert N. Brey;Nicholas J. Mantis;Nicholas J. Mantis

  • Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB)

    Anastasiya Yermakova;Nicholas J. Mantis;Nicholas J. Mantis

  • A functional role for ezrin during Shigella flexneri entry into epithelial cells.

    Anouchka Skoudy;Guy Tran Van Nhieu;Nicholas Mantis;Monique Arpin

  • Recognition of secretory IgA by DC-SIGN: Implications for immune surveillance in the intestine

    Jan Baumann;Chae Gyu Park;Nicholas J. Mantis

  • Stepwise engineering of heterodimeric single domain camelid VHH antibodies that passively protect mice from ricin toxin.

    David J. Vance;Jacqueline M. Tremblay;Nicholas J. Mantis;Charles B. Shoemaker

  • Folding domains within the ricin toxin A subunit as targets of protective antibodies.

    Joanne M. O’Hara;Lori M. Neal;Elizabeth A. McCarthy;Jane A. Kasten-Jolly

  • Characterization of a Novel High-Affinity Monoclonal Immunoglobulin G Antibody against the Ricin B Subunit

    Carolyn R. McGuinness;Nicholas J. Mantis

  • Serological Analysis Reveals an Imbalanced IgG Subclass Composition Associated with COVID-19 Disease Severity.

    Jennifer L. Yates;Dylan J. Ehrbar;Danielle T. Hunt;Roxanne C. Girardin

Frequent Co-Authors

C. Russell Middaugh
C. Russell Middaugh University of Kansas
David B. Volkin
David B. Volkin University of Kansas
Marian R. Neutra
Marian R. Neutra Harvard Medical School
C. Roy
C. Roy Centre national de la recherche scientifique, CNRS
Ellen S. Vitetta
Ellen S. Vitetta The University of Texas Southwestern Medical Center
Charles B. Shoemaker
Charles B. Shoemaker Tufts University
Blaise Corthésy
Blaise Corthésy University Hospital of Lausanne
Do Hyun Kim
Do Hyun Kim Korea Advanced Institute of Science and Technology
Kirsten Sandvig
Kirsten Sandvig Oslo University Hospital
Stephen C. Winans
Stephen C. Winans Cornell University

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