World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
14061
World Ranking
6466
National Ranking
27

Medicine

D-Index
74
Citations
14793
World Ranking
19516
National Ranking
48

Overview

Po-Lin Kuo is affiliated with Kaohsiung Medical University in Taiwan and has contributed to multiple fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Environmental Science. Their research work spans key subfields such as Cancer Research, Health, Toxicology and Mutagenesis, Molecular Biology, Rheumatology, and Clinical Biochemistry.

The research topics covered by Po-Lin Kuo include:

  • MicroRNA in disease regulation
  • Extracellular vesicles in disease
  • Advanced Glycation End Products research
  • Rheumatoid Arthritis Research and Therapies
  • Osteoarthritis Treatment and Mechanisms
  • Cell Adhesion Molecules Research
  • Heavy Metal Exposure and Toxicity

Recent papers authored or coauthored by Po-Lin Kuo highlight a focus on molecular mechanisms of diseases and environmental health impacts. These publications include:

  • High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery, 2020, Molecular Therapy
  • Dual Role of Chondrocytes in Rheumatoid Arthritis: The Chicken and the Egg, 2020, International Journal of Molecular Sciences
  • Association of low-level heavy metal exposure with risk of chronic kidney disease and long-term mortality, 2024, PLoS ONE
  • Identification of the Potential Prognostic Markers from the miRNA-lncRNA-mRNA Interactions for Metastatic Renal Cancer via Next-Generation Sequencing and Bioinformatics, 2020, Diagnostics
  • Associations of Bone Turnover Markers with Cognitive Function in Patients Undergoing Hemodialysis, 2020, Disease Markers

The venues where Po-Lin Kuo has published are varied and include:

  • Molecular Therapy
  • International Journal of Molecular Sciences
  • PLoS ONE
  • Diagnostics
  • Disease Markers

Coauthor collaborations are an important aspect of Po-Lin Kuo's research activity, with frequent collaborators including:

  • Wei-An Chang
  • Ya-Ling Hsu
  • Mei-Chuan Kuo
  • Ping-Hsun Wu
  • Yi-Chun Tsai

Best Publications

  • Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1.

    Hsu Yl;Hung Jy;Chang Wa;Lin Ys

  • Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

    Clay C.C. Wang;Yi-Ming Chiang;Yi-Ming Chiang;Shu-Chiao Sung;Ya-Ling Hsu

  • Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway

    Tsung-Hua Hsieh;Cheng-Fang Tsai;Chia-Yi Hsu;Po-Lin Kuo

  • Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN

    Ya-Ling Hsu;Jen-Yu Hung;Wei-An Chang;Shu-Fang Jian

  • Isoobtusilactone A Induces Cell Cycle Arrest and Apoptosis through Reactive Oxygen Species/Apoptosis Signal-Regulating Kinase 1 Signaling Pathway in Human Breast Cancer Cells

    Po-Lin Kuo;Chung-Yi Chen;Ya-Ling Hsu

  • 6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells.

    Jen-Yu Hung;Ya-Ling Hsu;Chien-Te Li;Ying-Chin Ko

  • Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation.

    Chia-Jung Hsieh;Po-Lin Kuo;Ying-Chan Hsu;Ya-Fang Huang

  • Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines

    Ya-Ling Hsu;Yu-Chun Kuo;Po-Lin Kuo;Lean-Teik Ng

  • Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/Snail signaling pathway

    Hsu Yl;Hou Mf;Kuo Pl;Huang Yf

  • Tumor Microenvironment: A New Treatment Target for Cancer

    Ming-Ju Tsai;Wei-An Chang;Ming-Shyan Huang;Po-Lin Kuo

  • Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis

    Ya Ling Hsu;Jen Yu Hung;Shin Yi Chiang;Shu Fang Jian

  • CXCL1/GROα increases cell migration and invasion of prostate cancer by decreasing fibulin-1 expression through NF-κB/HDAC1 epigenetic regulation.

    Po-Lin Kuo;Kun-Hung Shen;Shun-Hsing Hung;Ya-Ling Hsu

  • Lung Cancer-Derived Galectin-1 Mediates Dendritic Cell Anergy through Inhibitor of DNA Binding 3/IL-10 Signaling Pathway

    Po Lin Kuo;Jen Yu Hung;Shau Ku Huang;Shah Hwa Chou

  • MicroRNA-33a functions as a bone metastasis suppressor in lung cancer by targeting parathyroid hormone related protein.

    Po-Lin Kuo;Szi-Hui Liao;Jen-Yu Hung;Ming-Shyan Huang

  • The Role of Galectin-3 in the Kidneys

    Szu-Chia Chen;Po-Lin Kuo;Po-Lin Kuo

  • Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells.

    Jen-Yu Hung;Ya-Ling Hsu;Wen-Chiu Ni;Ying-Ming Tsai

  • Immunomodulatory effects of environmental endocrine disrupting chemicals.

    Chang-Hung Kuo;San-Nan Yang;Po-Lin Kuo;Chih-Hsing Hung

  • Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway

    Ya-Ling Hsu;Cheng-Ying Wu;Jen-Yu Hung;Yi-Shiuan Lin

  • Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor κB pathway ☆

    Ya-Ling Hsu;Po-Lin Kuo;Chien-Yu Cho;Wen-Chiu Ni

  • Lung Tumor-associated Osteoblast-derived Bone Morphogenetic Protein-2 Increased Epithelial-to-Mesenchymal Transition of Cancer by Runx2/Snail Signaling Pathway

    Ya-Ling Hsu;Ming-Shyan Huang;Chih-Jen Yang;Jen-Yu Hung

Frequent Co-Authors

Shau Ku Huang
Shau Ku Huang Shenzhen University
Ming-Lung Yu
Ming-Lung Yu Kaohsiung Medical University
Chih-Hsin Tang
Chih-Hsin Tang China Medical University
Fang Rong Chang
Fang Rong Chang Kaohsiung Medical University
Gautam Sethi
Gautam Sethi National University of Singapore

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