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Christian Schöneich

Christian Schöneich

D-Index & Metrics

Chemistry

D-Index
75
Citations
17859
World Ranking
4515
National Ranking
1422

Overview

Christian Schöneich is affiliated with the University of Kansas in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a particular focus on molecular biology as a subfield. They have published 66 works in main fields of study and have an additional focus in medicine, covering 30 publications.

Their research themes include protein purification and stability, monoclonal and polyclonal antibodies research, viral infectious diseases and gene expression in insects, innovative microfluidic and catalytic techniques innovation, free radicals and antioxidants, mass spectrometry techniques and applications, as well as inhalation and respiratory drug delivery.

Frequent coauthors in Schöneich's research include Yilue Zhang, Yaqi Wu, Natalia Subelzú, Anurag S. Rathore, and Maribel Espinoza Ballesteros, indicating collaboration on multiple projects within their specialization.

Publications by Schöneich appear regularly in several scientific venues. The most frequent publication venues include Molecular Pharmaceutics, Journal of Pharmaceutical Sciences, European Journal of Pharmaceutics and Biopharmaceutics, Pharmaceutical Research, and Free Radical Biology and Medicine.

Recent papers authored or co-authored by Schöneich include:

  • "Photo-Degradation of Therapeutic Proteins: Mechanistic Aspects," 2020, Pharmaceutical Research
  • "Designing Formulation Strategies for Enhanced Stability of Therapeutic Peptides in Aqueous Solutions: A Review," 2023, Pharmaceutics
  • "Azocompounds as generators of defined radical species: Contributions and challenges for free radical research," 2020, Free Radical Biology and Medicine
  • "Oxidation and Deamidation of Monoclonal Antibody Products: Potential Impact on Stability, Biological Activity, and Efficacy," 2021, Journal of Pharmaceutical Sciences
  • "The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case," 2022, Journal of Pharmaceutical Sciences

Best Publications

  • S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

    Takeshi Adachi;Robert M Weisbrod;David R Pimentel;Jia Ying

  • Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease

    Christian Schöneich

  • SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

    Maged M. Harraz;Jennifer J. Marden;Weihong Zhou;Yulong Zhang

  • Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization

    Shihong Li;Christian Schöneich;Ronald T. Borchardt

  • Oxidative degradation of pharmaceuticals: theory, mechanisms and inhibition.

    Susan W. Hovorka;Christian Schöneich

  • Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.

    Rosa I. Viner;Deborah A. Ferrington;Todd D. Williams;Diana J. Bigelow

  • Peroxynitrite modification of protein thiols: oxidation, nitrosylation, and S-glutathiolation of functionally important cysteine residue(s) in the sarcoplasmic reticulum Ca-ATPase.

    Rosa I. Viner;Todd D. Williams;Christian Schoneich

  • Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release

    Wim Jiskoot;Theodore W. Randolph;David B. Volkin;C. Russell Middaugh

  • Proteomic identification of 3-nitrotyrosine-containing rat cardiac proteins: effects of biological aging.

    Jaroslaw Kanski;Antje Behring;Jill Pelling;Christian Schöneich

  • Oxidation of Therapeutic Proteins and Peptides: Structural and Biological Consequences

    Riccardo Torosantucci;Christian Schöneich;Wim Jiskoot

  • Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry.

    Jaroslaw Kanski;Sung J. Hong;Christian Schöneich

  • Free Radical Reactions of Methionine in Peptides: Mechanisms Relevant to β-Amyloid Oxidation and Alzheimer's Disease

    Christian Schöneich;Dariusz Pogocki;Gordon L. Hug;Krzysztof Bobrowski

  • Diastereoselective reduction of protein-bound methionine sulfoxide by methionine sulfoxide reductase.

    Victor S. Sharov;Deborah A. Ferrington;Thomas C. Squier;Christian Schöneich

  • Reactive oxygen species and biological aging: a mechanistic approach.

    Christian Schöneich

  • Nitration and inactivation of tyrosine hydroxylase by peroxynitrite.

    Béatrice Blanchard-Fillion;José M. Souza;José M. Souza;Thomas Friel;George C.T. Jiang

  • Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.

    Shanqin Xu;Jia Ying;Bingbing Jiang;Wei Guo

  • Loss of conformational stability in calmodulin upon methionine oxidation.

    Jun Gao;Daniel H. Yin;Yihong Yao;Hongye Sun

  • The Oxidative Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase by Peroxynitrite

    Rosa I. Viner;Andreas F.R. Hühmer;Diana J. Bigelow;Christian Schöneich

  • Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: a peroxynitrite-mediated process?

    Rosa I. Viner;Deborah A. Ferrington;Andreas F.R. Hühmer;Diana J. Bigelow

  • S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells

    Nicolas Clavreul;Takeshi Adachi;David R. Pimental;Yasuo Ido

Frequent Co-Authors

C. Russell Middaugh
C. Russell Middaugh University of Kansas
David B. Volkin
David B. Volkin University of Kansas
Richard S. Glass
Richard S. Glass University of Arizona
Wim Jiskoot
Wim Jiskoot Leiden University
Michael J. Davies
Michael J. Davies University of Copenhagen
Ronald T. Borchardt
Ronald T. Borchardt University of Kansas
Deborah A. Ferrington
Deborah A. Ferrington University of Minnesota
John F. Carpenter
John F. Carpenter University of Colorado Anschutz Medical Campus
Richard A. Cohen
Richard A. Cohen Boston University

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