2023 - Research.com Microbiology in Taiwan Leader Award
2022 - Research.com Microbiology in Taiwan Leader Award
2006 - Fellow, The World Academy of Sciences
2002 - Fellow of the American Academy of Microbiology RNA Viruses
His scientific interests lie mostly in Molecular biology, RNA, Virology, RNA-dependent RNA polymerase and Hepatitis C virus. His biological study spans a wide range of topics, including Cell culture, Viral replication, Gene, Cytidine deaminase and RNase P. The RNA study combines topics in areas such as Replicon and Transcription.
His Virology research is multidisciplinary, relying on both RNA polymerase and Cholesterol. His RNA-dependent RNA polymerase study integrates concerns from other disciplines, such as Non-coding RNA, RNA editing and RNA silencing. His Hepatitis C virus research is multidisciplinary, incorporating perspectives in Interferon, Toll-like receptor and Protein biosynthesis.
Michael M. C. Lai spends much of his time researching Virology, RNA, Molecular biology, Virus and RNA-dependent RNA polymerase. In general Virology, his work in Viral replication and Hepatitis C virus is often linked to Mouse hepatitis virus and Coronavirus linking many areas of study. Michael M. C. Lai interconnects Transcription and Intron in the investigation of issues within RNA.
Michael M. C. Lai works mostly in the field of Molecular biology, limiting it down to topics relating to NS5B and, in certain cases, NS5A, as a part of the same area of interest. His Virus research includes themes of Immune system and Antigen. His study in RNA-dependent RNA polymerase is interdisciplinary in nature, drawing from both RNA silencing, RNA editing and RNA polymerase.
Michael M. C. Lai mostly deals with Virology, Virus, Viral replication, Hepatitis C virus and Cell biology. Michael M. C. Lai combines subjects such as RNA, RNA-dependent RNA polymerase and Pathogenesis with his study of Virology. His studies in Virus integrate themes in fields like Cirrhosis and Antigen.
The concepts of his Hepatitis C virus study are interwoven with issues in Carcinogenesis, Cancer research, Antibody and Gene silencing. His Cell biology study combines topics in areas such as Autophagy, NS5A and Endosome. In his study, Molecular biology is strongly linked to MRE11 Homologue Protein, which falls under the umbrella field of DNA repair.
Michael M. C. Lai mainly investigates Virology, Cell biology, Viral replication, Viral entry and DNA repair. His work on RNA-dependent RNA polymerase expands to the thematically related Virology. Michael M. C. Lai is investigating Transcription and RNA as part of his examination of RNA-dependent RNA polymerase.
His work in Viral replication tackles topics such as NS5A which are related to areas like Cell cycle, RNA interference, Cell growth, Gene Knockdown Techniques and NS5B. As part of one scientific family, Michael M. C. Lai deals mainly with the area of Viral entry, narrowing it down to issues related to the Viral matrix protein, and often Viral structural protein and Virus maturation. In DNA, Michael M. C. Lai works on issues like Molecular biology, which are connected to NS3.
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The molecular biology of coronaviruses
Michael M.C. Lai;David Cavanagh.
Advances in Virus Research (1997)
Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein
Deborah R. Taylor;Stephanie T. Shi;Patrick R. Romano;Glen N. Barber.
RNA recombination in animal and plant viruses.
M. M. C. Lai.
Microbiological Research (1992)
Hepatitis C Virus Core Protein Binds to the Cytoplasmic Domain of Tumor Necrosis Factor (TNF) Receptor 1 and Enhances TNF-Induced Apoptosis
Nongliao Zhu;Ali Khoshnan;Robert Schneider;Masayuki Matsumoto.
Journal of Virology (1998)
Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail
Carlo Moscovici;Carlo Moscovici;M.Giovannella Moscovici;M.Giovannella Moscovici;Humberto Jimenez;Humberto Jimenez;Michael M.C. Lai.
Putative papain-related thiol proteases of positive-strand RNA viruses Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, α- and coronaviruses
Alexander E. Gorbalenya;Eugene V. Koonin;Michael M.-C. Lai.
FEBS Letters (1991)
Coronaviridae: the viruses and their replication
M. M. C. Lai;K. V. Holmes.
In: Fields Virology 1 (2001)
Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft.
Lu Gao;Hideki Aizaki;Jian-Wen He;Michael M. C. Lai.
Journal of Virology (2004)
The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase.
Han-Jung Lee;Chien-Kou Shieh;Alexander E. Gorbalenya;Eugene V. Koonin.
Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins
Stephanie T. Shi;Stephen J. Polyak;Hong Tu;Deborah R. Taylor.
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