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Biology and Biochemistry

D-Index
53
Citations
30658
World Ranking
15877
National Ranking
6594

Research.com Recognitions

  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

George A. Gutman is affiliated with the University of California, Irvine in the United States. Their research is primarily situated at the intersection of biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology and cardiology and cardiovascular medicine. The scientist's contributions extend to subfields including cellular and molecular neuroscience and organic chemistry.

Their scholarly output covers several core topics, notably:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nicotinic acetylcholine receptors study
  • Neuroscience and neuropharmacology research
  • Coordination chemistry and organometallics

Gutman has published multiple papers primarily in the venue IUPHAR/BPS Guide to Pharmacology CITE, with at least six contributions recorded there. Notable recent papers include:

  • Voltage-gated potassium channels (Kv) in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Voltage-gated potassium channels (Kv) in GtoPdb v.2021.3, 2021, IUPHAR/BPS Guide to Pharmacology CITE
  • Calcium- and sodium-activated potassium channels (KCa, KNa) in GtoPdb v.2021.3, 2021, IUPHAR/BPS Guide to Pharmacology CITE
  • Calcium- and sodium-activated potassium channels (KCa, KNa) in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Calcium- and sodium-activated potassium channels (KCa, KNa) in GtoPdb v.2025.3, 2025, IUPHAR/BPS Guide to Pharmacology CITE

Frequent collaborators associated with Gutman's work include:

  • Stephan Grissmer
  • K. George Chandy
  • Bernard Attali
  • M. Hunter Giese
  • Lily Yeh Jan

In recognition of contributions to scientific research, Gutman was named a Fellow of the American Association for the Advancement of Science (AAAS) in 1992.

Best Publications

  • International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

    W. A. Catterall;K. G. Chandy;D. E. Clapham;G. A. Gutman

  • Slipped-strand mispairing: a major mechanism for DNA sequence evolution.

    G Levinson;G A Gutman

  • International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels

    Aguan D. Wei;George A. Gutman;Richard W Aldrich;K. George Chandy

  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.

    S. Grissmer;A. N. Nguyen;Jayashree Aiyar;D. C. Hanson

  • Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

    Christine Beeton;Heike Wulff;Nathan E. Standifer;Philippe Azam

  • Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily

    Frank H. Yu;Vladimir Yarov-Yarovoy;George A. Gutman;William A. Catterall

  • International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels

    George A. Gutman;K. George Chandy;John P. Adelman;Jayashree Aiyar

  • K+ channels as targets for specific immunomodulation.

    K. George Chandy;Heike Wulff;Christine Beeton;Michael Pennington

  • High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12

    Gene Levinson;George A. Gutman

  • Up-regulation of the IKCa1 Potassium Channel during T-cell Activation MOLECULAR MECHANISM AND FUNCTIONAL CONSEQUENCES

    Sanjiv Ghanshani;Heike Wulff;Mark J. Miller;Heike Rohm

  • A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.

    Jan Tytgat;K.George Chandy;Maria L Garcia;George A Gutman

  • Nonrandom utilization of codon pairs in Escherichia coli

    G A Gutman;G W Hatfield

  • ShK-Dap22, a Potent Kv1.3-specific Immunosuppressive Polypeptide

    Katalin Kalman;Michael W. Pennington;Mark D. Lanigan;Angela Nguyen

  • Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins

    Jayashree Aiyar;Jane M. Withka;James P. Rizzi;David H. Singleton

  • Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases

    Christine Beeton;Michael W. Pennington;Heike Wulff;Satendra Singh

  • Monoclonal antibodies against rat immunoglobulin kappa chains.

    Lewis L. Lanier;George A. Gutman;Dorothy E. Lewis;Susan T. Griswold

  • Lymphoid tissue architecture: Experimental analysis of the origin and distribution of T-cells and B-cells

    G. A. Gutman;I. L. Weissman

  • IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels

    Anthony J. Harmar;Rebecca A. Hills;Edward M. Rosser;Martin Jones

  • Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?

    KG Chandy;E Fantino;O Wittekindt;K Kalman

  • Expression and chromosomal localization of a lymphocyte K+ channel gene.

    S Grissmer;B Dethlefs;J J Wasmuth;A L Goldin

Frequent Co-Authors

K. George Chandy
K. George Chandy Nanyang Technological University
Michael D. Cahalan
Michael D. Cahalan University of California, Irvine
Heike Wulff
Heike Wulff University of California, Davis
Michael W. Pennington
Michael W. Pennington University of Florida
Irving L. Weissman
Irving L. Weissman Stanford University
Vikram G. Shakkottai
Vikram G. Shakkottai The University of Texas Southwestern Medical Center
Bert L. Semler
Bert L. Semler University of California, Irvine
William A. Catterall
William A. Catterall University of Washington
Raymond S. Norton
Raymond S. Norton Monash University
Noel L. Warner
Noel L. Warner Becton Dickinson (United States)

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