Edwin G. Krebs

Research.com Recognitions

• 2008 - Distinguished Scientist Award, American Heart Association
• 1992 - Nobel Prize for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism
• 1991 - Welch Award in Chemistry, Robert A. Welch Foundation
• 1989 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
• 1978 - Canada Gairdner International Award
• 1973 - Member of the National Academy of Sciences
• 1966 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Best Publications

• The MAPK signaling cascade.

  Rony Seger;Edwin G. Krebs

  4880
  Citations

• An Adenosine 3',5'-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

  D. A. Walsh;John P. Perkins;Edwin G. Krebs

  2069
  Citations

• Protein Serine/Threonine Kinases

  Arthur M. Edelman;Donald K. Blumenthal;Edwin G. Krebs

  1850
  Citations

• Purification and Characterization of a Protein Inhibitor of Adenosine 3',5'-Monophosphate-dependent Protein Kinases

  Donal A. Walsh;Charles D. Ashby;Carmen Gonzalez;Dianne Calkins

  1259
  Citations

• Purification and properties of rabbit skeletal muscle adenosine 3',5'-monophosphate-dependent protein kinases.

  Erwin M. Reimann;Donal A. Walsh;Edwin G. Krebs

  1142
  Citations

• Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

  B E Kemp;D J Graves;E Benjamini;E G Krebs

  1036
  Citations

• The isolation and crystallization of rabbit skeletal muscle phosphorylase b.

  Edmond H. Fischer;Edwin G. Krebs

  911
  Citations

• PURIFICATION AND PROPERTIES OF RABBIT SKELETAL MUSCLE PHOSPHORYLASE B KINASE.

  Edwin G. Krebs;David S. Love;Gloria E. Bratvold;Kenneth A. Trayser

  756
  Citations

• A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

  Jamey D. Marth;Richard Peet;Richard Peet;Edwin G. Krebs;Roger M. Perlmutter;Roger M. Perlmutter

  691
  Citations

• Comparison of adenosine 3':5'-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle.

  F Hofmann;J A Beavo;P J Bechtel;E G Krebs

  687
  Citations

• [43] Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle

  J.A. Beavo;P.J. Bechtel;E.G. Krebs

  679
  Citations

• Conversion of phosphorylase b to phosphorylase a in muscle extracts

  Edmond H. Fischer;Edwin G. Krebs

  659
  Citations

• Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae.

  T. Toda;S. Cameron;P. Sass;M. Zoller

  649
  Citations

• Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

  Jyoti J. Watters;Jean S. Campbell;Matthew J. Cunningham;Edwin G. Krebs

  636
  Citations

• Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase.

  N G Ahn;R Seger;R L Bratlien;C D Diltz

  630
  Citations

• The phosphorylase b to a converting enzyme of rabbit skeletal muscle.

  Edwin G. Krebs;Edmond H. Fischer

  624
  Citations

• Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation.

  Karin E. Bornfeldt;Elaine W. Raines;Toru Nakano;Lee M. Graves

  594
  Citations

• Factors affecting the activity of muscle phosphorylase b kinase.

  Edwin G. Krebs;Donald J. Graves;Edmond H. Fischer

  573
  Citations

• Substrate specificity determinants for casein kinase II as deduced from studies with synthetic peptides.

  Elizabeth A. Kuenzel;Jenny A. Mulligan;James Sommercorn;Edwin G. Krebs

  571
  Citations

• Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

  Lee M. Graves;Karin E. Bornfeldt;Elaine W. Raines;Brian C. Potts

  570
  Citations