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Molecular Biology

D-Index
86
Citations
29238
World Ranking
821
National Ranking
433

Overview

Natalie G. Ahn is affiliated with the University of Colorado Boulder in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology as a subfield. Additional areas of study include Cell Biology, Computational Theory and Mathematics, Materials Chemistry, and Geophysics.

The scientist's work covers several main topics, including:

  • Melanoma and MAPK Pathways
  • Protein Kinase Regulation and GTPase Signaling
  • Computational Drug Discovery Methods
  • Protein Structure and Dynamics
  • Enzyme Structure and Function
  • Protein Degradation and Inhibitors
  • PI3K/AKT/mTOR signaling in cancer

Recent papers authored or co-authored by Natalie G. Ahn include:

  • Intermittent treatment of BRAF V600E melanoma cells delays resistance by adaptive resensitization to drug rechallenge, 2022, Proceedings of the National Academy of Sciences
  • Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol O-methyltransferase reaction, 2020, Proceedings of the National Academy of Sciences
  • Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2, 2020, Biochemistry
  • Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2, 2024, eLife
  • Molecular insight into the specific interactions of the SARS-Coronavirus-2 nucleocapsid with RNA and host protein, 2023, Protein Science

Frequent co-authors who have collaborated with Natalie G. Ahn include:

  • Laurel M. Pegram
  • David N. M. Jones
  • Jake W. Anderson
  • David Vaisar
  • Guy Vigers

Their work has been published repeatedly in venues such as:

  • Proceedings of the National Academy of Sciences
  • eLife
  • Current Opinion in Structural Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemistry

Best Publications

  • Signal transduction through MAP kinase cascades.

    Timothy S. Lewis;Paul S. Shapiro;Natalie G. Ahn

  • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

    Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet

  • Transformation of mammalian cells by constitutively active MAP kinase kinase

    S. J. Mansour;W. T. Matten;A. S. Hermann;J. M. Candia

  • Comparison of Label-free Methods for Quantifying Human Proteins by Shotgun Proteomics

    William M. Old;Karen Meyer-Arendt;Lauren Aveline-Wolf;Kevin G. Pierce

  • Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

    Nicholas S. Duesbery;Craig P. Webb;Stephen H. Leppla;Valery M. Gordon

  • Mapping protein post-translational modifications with mass spectrometry

    Eric S Witze;William M Old;Katheryn A Resing;Natalie G Ahn

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase.

    N G Ahn;R Seger;R L Bratlien;C D Diltz

  • Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

    Jeffrey A. Frost;Helge Steen;Helge Steen;Paul Shapiro;Tim Lewis

  • Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro.

    J Posada;N Yew;N G Ahn;G F Vande Woude

  • Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells.

    Rony Seger;Natalie G. Ahn;James Posada;Erlynda S. Munar

  • PROTEIN ANALYSIS BY HYDROGEN EXCHANGE MASS SPECTROMETRY

    Andrew N. Hoofnagle;Katheryn A. Resing;Natalie G. Ahn

  • Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: Implications for their mechanism of activation

    Rony Seger;Natalie G. Ahn;Teri G. Boulton;George D. Yancopoulos

  • Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells.

    N G Ahn;J E Weiel;C P Chan;E G Krebs

  • ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ

    John W. Haycock;Natalie G. Ahn;Melanie H. Cobb;Edwin G. Krebs

  • The mitogen-activated protein kinase activator.

    Natalie G. Ahn;Rony Seger;Edwin G. Krebs

  • Docking Motif Interactions in MAP Kinases Revealed by Hydrogen Exchange Mass Spectrometry

    Thomas Lee;Andrew N Hoofnagle;Yukihito Kabuyama;James Stroud

  • Identification of Novel MAP Kinase Pathway Signaling Targets by Functional Proteomics and Mass Spectrometry

    Timothy S. Lewis;John B. Hunt;Lauren D. Aveline;Karen R. Jonscher

  • Mitogen-Activated Protein Kinases (Erk1,2) Phosphorylate Lys-Ser-Pro (KSP) Repeats in Neurofilament Proteins NF-H and NF-M

    Veeranna;Niranjana D. Amin;Natalie G. Ahn;Howard Jaffe

  • Oncogenes and Tumor Angiogenesis: Differential Modes of Vascular Endothelial Growth Factor Up-Regulation in ras-transformed Epithelial Cells and Fibroblasts

    Janusz Rak;Yoshihiro Mitsuhashi;Cap Sheehan;Ami Tamir

Frequent Co-Authors

Katheryn A. Resing
Katheryn A. Resing University of Colorado Boulder
Rony Seger
Rony Seger Weizmann Institute of Science
Judith P. Klinman
Judith P. Klinman University of California, Berkeley
Edwin G. Krebs
Edwin G. Krebs University of Washington
Karolin Luger
Karolin Luger University of Colorado Boulder
Melanie H. Cobb
Melanie H. Cobb The University of Texas Southwestern Medical Center
David A. Norris
David A. Norris University of Colorado Anschutz Medical Campus
Krzysztof J. Cios
Krzysztof J. Cios Virginia Commonwealth University
Kristi S. Anseth
Kristi S. Anseth University of Colorado Boulder
Jean S. Campbell
Jean S. Campbell University of Washington

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