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Medicine
Switzerland
2023

D-Index & Metrics

Medicine

D-Index
110
Citations
45701
World Ranking
5555
National Ranking
69

Research.com Recognitions

  • 2023 - Research.com Medicine in Switzerland Leader Award

Overview

Bernard Thorens is affiliated with the University of Lausanne in Switzerland. Their research primarily focuses on medicine, with notable contributions to biochemistry, genetics, and molecular biology. The scientist's work spans several subfields including surgery, endocrinology, diabetes and metabolism, physiology, molecular biology, and genetics.

The main topics of Bernard Thorens' research include pancreatic function and diabetes, regulation of appetite and obesity, diabetes treatment and management, diabetes and associated disorders, adipose tissue and metabolism, metabolism related to diabetes and cancer, and diabetes management and research.

Bernard Thorens has published in various frequent venues, including:

  • Diabetologia
  • Diabetes
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Metabolism
  • Nature Metabolism

Recent significant papers by Bernard Thorens and collaborators include:

  • "Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes," 2021, published in Nature Metabolism
  • "GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration," 2020, published in Science Translational Medicine
  • "Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes," 2020, published in Cell Reports
  • "Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study," 2021, published in Diabetologia
  • "Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study," 2021, published in Diabetes

Bernard Thorens frequently collaborates with several researchers, with notable coauthors including:

  • Mark Ibberson
  • Guy A. Rutter
  • Ana Rodríguez Sánchez-Archidona
  • Alexandre Picard
  • Florence Mehl

Best Publications

  • Thioredoxin-interacting protein links oxidative stress to inflammasome activation

    Rongbin Zhou;Aubry Tardivel;Bernard Thorens;Inpyo Choi

  • The SLC2 (GLUT) family of membrane transporters.

    Mike Mueckler;Bernard Thorens

  • Glucose transporters in the 21st Century

    Bernard Thorens;Mike M. Mueckler

  • Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

    Bernard Thorens

  • Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells

    Thorens B;Sarkar Hk;Kaback Hr;Lodish Hf

  • The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review).

    Hans-Georg Joost;Bernard Thorens

  • Uric acid transport and disease.

    Alexander So;Bernard Thorens

  • Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor.

    Bernard Thorens;Andrée Porret;Léo Bühler;Shao-Ping Deng

  • GLUT2, glucose sensing and glucose homeostasis

    Bernard Thorens

  • Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase.

    Hervé Duplain;Rémy Burcelin;Claudio Sartori;Stéphane Cook

  • The SLC2 family of facilitated hexose and polyol transporters

    Marc Uldry;Bernard Thorens

  • International Union of Pharmacology. XXXV. The Glucagon Receptor Family

    Kelly E. Mayo;Laurence J. Miller;Dominique Bataille;Stéphane Dalle

  • Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

    Mario Pende;Sara C. Kozma;Muriel Jaquet;Viola Oorschot

  • Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators

    Hans Georg Joost;Graeme I. Bell;James D. Best;Morris J. Birnbaum

  • Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

    M T Guillam;E Hümmler;E Schaerer;J I Yeh

  • Short-Term Overexpression of a Constitutively Active Form of AMP-Activated Protein Kinase in the Liver Leads to Mild Hypoglycemia and Fatty Liver

    Marc Foretz;Nicolas Ancellin;Fabrizio Andreelli;Yannick Saintillan

  • The Role of SGLT1 and GLUT2 in Intestinal Glucose Transport and Sensing

    Pia V. Röder;Kerstin E. Geillinger;Tamara S. Zietek;Bernard Thorens

  • Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

    Bernard Thorens;Bernard Thorens;Jean-Jacques Mermod;Pierre Vassalli

  • Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes

    Thorens B

  • GLUT2 is a high affinity glucosamine transporter.

    Marc Uldry;Mark Ibberson;Masaya Hosokawa;Bernard Thorens

Frequent Co-Authors

Guy A. Rutter
Guy A. Rutter Imperial College London
Christian Widmann
Christian Widmann University of Lausanne
Marc Foretz
Marc Foretz Université Paris Cité
Gérard Waeber
Gérard Waeber University of Lausanne
Piero Marchetti
Piero Marchetti University of Pisa
Rolf Gruetter
Rolf Gruetter École Polytechnique Fédérale de Lausanne
Daniel J. Drucker
Daniel J. Drucker Lunenfeld-Tanenbaum Research Institute
Philippe Froguel
Philippe Froguel Imperial College London

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