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Biology and Biochemistry

D-Index
60
Citations
14024
World Ranking
11882
National Ranking
219

Overview

Harry Heimberg is affiliated with Vrije Universiteit Brussel in Belgium. Their research primarily focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. Their subfields of expertise include surgery, genetics, molecular biology, oncology, and endocrinology, diabetes, and metabolism.

The main topics of Harry Heimberg's research include pancreatic function and diabetes, diabetes and associated disorders, pancreatic and hepatic oncology research, diabetes management and research, pluripotent stem cells research, genetics and neurodevelopmental disorders, and epigenetics and DNA methylation.

They have published several papers addressing various aspects of pancreatic biology and diabetes. Recent publications include:

  • Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas, 2021, Cell stem cell
  • Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?, 2021, Cells
  • Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease, 2021, Gut
  • Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas, 2023, Cell stem cell
  • Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice, 2020, Nature Biotechnology

Frequent coauthors in their research include:

  • Gunter Leuckx
  • Luc Bouwens
  • Yves Heremans
  • Sandrina Martens
  • Katarina Coolens

Their work appears repeatedly in prominent scientific venues such as Cell stem cell, bioRxiv (Cold Spring Harbor Laboratory), Cells, Gut, and Nature Biotechnology.

Best Publications

  • Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas.

    Xiaobo Xu;Joke D'Hoker;Joke D'Hoker;Geert Stange;Geert Stange;Stefan Bonné;Stefan Bonné

  • Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

    Meritxell Huch;Paola Bonfanti;Sylvia F Boj;Toshiro Sato

  • The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

    Patrick Collombat;Xiaobo Xu;Philippe Ravassard;Philippe Ravassard;Beatriz Sosa-Pineda

  • Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

    Myriam Solar;Carina Cardalda;Isabelle Houbracken;Isabelle Houbracken;Mercè Martín

  • Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression.

    Anick De Vos;Henry Heimberg;Erik Quartier;Peter Huypens

  • Glucose Sensing in Pancreatic β-Cells: A Model for the Study of Other Glucose-Regulated Cells in Gut, Pancreas, and Hypothalamus

    Franciscus Schuit;Peter Huypens;Henry Heimberg;Daniel Pipeleers

  • A Comprehensive Analysis of Cytokine-induced and Nuclear Factor-κB-dependent Genes in Primary Rat Pancreatic β-Cells

    Alessandra K. Cardozo;Harry Heimberg;Yves Heremans;Ruth Leeman

  • Spatiotemporal patterns of multipotentiality in Ptf1a -expressing cells during pancreas organogenesis and injury-induced facultative restoration

    Fong Cheng Pan;Eric D. Bankaitis;Daniel Boyer;Xiaobo Xu

  • Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.

    Harry Heimberg;Yves Heremans;Christian Jobin;Ruth Leemans

  • The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.

    Monica Courtney;Elisabet Gjernes;Noémie Druelle;Christophe Ravaud;Christophe Ravaud;Christophe Ravaud

  • Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells

    Karen Moens;Harry Heimberg;Daisy Flamez;Peter Huypens

  • Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis

    Nouha Ben-Othman;Andhira Vieira;Monica Courtney;Fabien Record

  • Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

    Yves Heremans;Mark Van De Casteele;Peter in't Veld;Gerard Gradwohl

  • Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro.

    Ilse Rooman;Yves Heremans;Henry Heimberg;Luc Bouwens

  • Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization

    Harry Heimberg;Anick De Vos;Daniel Pipeleers;Bernard Thorens

  • AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase

    B A Kefas;Y Cai;Z Ling;H. Heimberg

  • Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.

    Keith Al-Hasani;Anja Pfeifer;Anja Pfeifer;Anja Pfeifer;Monica Courtney;Monica Courtney;Monica Courtney;Nouha Ben-Othman;Nouha Ben-Othman;Nouha Ben-Othman

  • IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

    Georg Mellitzer;Stefan Bonné;Reini F Luco;Mark Van De Casteele

  • Heterogeneity in Glucose Sensitivity Among Pancreatic Beta-cells Is Correlated To Differences in Glucose Phosphorylation Rather Than Glucose-transport

    H Heimberg;A De Vos;A Vandercammen;E Van Schaftingen

  • Glucosamine-induced Insulin Resistance in 3T3-L1 Adipocytes Is Caused by Depletion of Intracellular ATP

    Richard C. Hresko;Harry Heimberg;Maggie M.-Y. Chi;Mike Mueckler

Frequent Co-Authors

Daniel Pipeleers
Daniel Pipeleers Vrije Universiteit Brussel
Luc Bouwens
Luc Bouwens Vrije Universiteit Brussel
Yuval Dor
Yuval Dor Hebrew University of Jerusalem
Frans Schuit
Frans Schuit KU Leuven
Philippe Ravassard
Philippe Ravassard Université Paris Cité
Ahmed Mansouri
Ahmed Mansouri Max Planck Society
Palle Serup
Palle Serup University of Copenhagen
Michael S. German
Michael S. German University of California, San Francisco
Jorge Ferrer
Jorge Ferrer Imperial College London

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