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Microbiology

D-Index
94
Citations
33680
World Ranking
565
National Ranking
60

Overview

Brendan W. Wren is affiliated with the London School of Hygiene & Tropical Medicine in the United Kingdom. Their research primarily intersects the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

The main topics addressed in Brendan W. Wren's work include:

  • Salmonella and Campylobacter epidemiology
  • Viral gastroenteritis research and epidemiology
  • Escherichia coli research studies
  • Bacteriophages and microbial interactions
  • Pneumonia and Respiratory Infections
  • Legionella and Acanthamoeba research
  • Vibrio bacteria research studies

Key recent publications by Brendan W. Wren showcase diverse aspects of microbial pathogenesis and host interactions:

  • "Revisiting Campylobacter jejuni Virulence and Fitness Factors: Role in Sensing, Adapting, and Competing", 2021, Frontiers in Cellular and Infection Microbiology
  • "Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter", 2020, Microbiome
  • "Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile", 2021, Scientific Reports
  • "Improving protein glycan coupling technology (PGCT) for glycoconjugate vaccine production", 2020, Expert Review of Vaccines
  • "Use of Precision-Cut Tissue Slices as a Translational Model to Study Host-Pathogen Interaction", 2021, Frontiers in Veterinary Science

Brendan W. Wren frequently publishes in several venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbial Cell Factories
  • Frontiers in Cellular and Infection Microbiology
  • Vaccines
  • Frontiers in Veterinary Science

The scientist collaborates extensively with recurrent co-authors who have contributed significantly to shared research efforts. Notable collaborators include:

  • Jon Cuccui
  • Sam Willcocks
  • Fauzy Nasher
  • Vanessa S. Terra
  • Ian J. Passmore

Within the subfields of study, Brendan W. Wren's work is categorized under:

  • Endocrinology
  • Infectious Diseases
  • Molecular Biology
  • Food Science
  • Epidemiology

Best Publications

  • The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences

    J. Parkhill;B. W. Wren;K. Mungall;J. M. Ketley

  • Genome sequence of Yersinia pestis , the causative agent of plague

    J. Parkhill;B. W. Wren;N. R. Thomson;R. W. Titball

  • The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

    Mohammed Sebaihia;Brendan W Wren;Peter Mullany;Neil F Fairweather

  • N-Linked Glycosylation in Campylobacter jejuni and Its Functional Transfer into E. coli

    Michael Wacker;Dennis Linton;Paul G. Hitchen;Mihai Nita-Lazar

  • Emergence and global spread of epidemic healthcare-associated Clostridium difficile.

    Miao He;Fabio Miyajima;Paul Roberts;Louise Ellison

  • The complete genome sequence of Francisella tularensis, the causative agent of tularemia.

    Pär Larsson;Petra C F Oyston;Patrick Chain;May C Chu

  • Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

    Richard A. Stabler;Miao-Xia He;Lisa Dawson;Melissa Martin

  • Protein glycosylation in bacterial mucosal pathogens

    Christine M. Szymanski;Brendan W. Wren

  • The HtrA family of serine proteases

    Mark J. Pallen;Brendan W. Wren

  • The yersiniae--a model genus to study the rapid evolution of bacterial pathogens.

    Brendan W. Wren

  • Evolutionary dynamics of Clostridium difficile over short and long time scales

    Miao He;Mohammed Sebaihia;Trevor D. Lawley;Richard A. Stabler

  • The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor

    Laura J. Deakin;Simon Clare;Robert P. Fagan;Lisa F. Dawson

  • Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.

    Trevor D. Lawley;Simon Clare;Alan W. Walker;David Goulding

  • Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity.

    Nick Dorrell;Joseph A. Mangan;Kenneth G. Laing;Jason Hinds

  • Bacterial pathogenomics

    Unknown

  • Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity

    Andrey V. Karlyshev;Dennis Linton;Norman A. Gregson;Albert J. Lastovica

  • Biofilm formation in Campylobacter jejuni.

    G. W. P Joshua;C. Guthrie-Irons;A. V. Karlyshev;B. W. Wren

  • Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway.

    Dennis Linton;Nick Dorrell;Paul G. Hitchen;Saba Amber

  • Phase variation of a β‐1,3 galactosyltransferase involved in generation of the ganglioside GM1‐like lipo‐oligosaccharide of Campylobacter jejuni

    Dennis Linton;Michel Gilbert;Paul G. Hitchen;Anne Dell

  • The response regulator PhoP is important for survival under conditions of macrophage-induced stress and virulence in Yersinia pestis.

    Petra C. F. Oyston;Nick Dorrell;Kerstin Williams;Shu-Rui Li

  • Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence

    Ozan Gundogdu;Stephen D Bentley;Matt T Holden;Julian Parkhill

Frequent Co-Authors

Andrey V. Karlyshev
Andrey V. Karlyshev Kingston University
Richard W. Titball
Richard W. Titball University of Exeter
Duncan J. Maskell
Duncan J. Maskell University of Melbourne
Paul R. Langford
Paul R. Langford Imperial College London
Julian Parkhill
Julian Parkhill University of Cambridge
Gordon Dougan
Gordon Dougan University of Cambridge
Petra C. F. Oyston
Petra C. F. Oyston Defence Science and Technology Laboratory
Matthew T. G. Holden
Matthew T. G. Holden University of St Andrews
Anne Dell
Anne Dell Imperial College London
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute

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