Douglas B. Kuhns mostly deals with Immunology, Mutation, Chronic granulomatous disease, Molecular biology and Leukemia. His Immunology research is multidisciplinary, incorporating perspectives in Missense mutation and Genetic enhancement. His research integrates issues of Protein inhibitor of activated STAT, Microbiology, Transactivation, Disseminated coccidioidomycosis and STAT1 in his study of Mutation.
His study focuses on the intersection of Chronic granulomatous disease and fields such as NADPH oxidase with connections in the field of Gene, X chromosome and Frameshift mutation. His Molecular biology research integrates issues from Interleukin 18, CXCL2, CCR1 and Signal transduction, Kinase activity. The study incorporates disciplines such as GATA2 Deficiency, Cancer research and Monocytopenia, MonoMAC in addition to Leukemia.
Douglas B. Kuhns spends much of his time researching Immunology, Chronic granulomatous disease, Molecular biology, Internal medicine and Immunodeficiency. His work in Immunology addresses issues such as Mutation, which are connected to fields such as Genotype. Douglas B. Kuhns combines subjects such as NADPH oxidase, CYBB, Inflammatory bowel disease, Phagocyte and Gene with his study of Chronic granulomatous disease.
His Molecular biology study incorporates themes from Kinase, Interleukin 8 and Exon. His Internal medicine study also includes fields such as
Gastrointestinal disease and Pathology most often made with reference to Gastroenterology,
Endocrinology together with Lactoferrin. His research on Immunodeficiency also deals with topics like
Colitis that connect with fields like CD18 and Leukocyte adhesion deficiency-1,
Immune dysregulation which intersects with area such as Phenotype.
The scientist’s investigation covers issues in Immunology, Chronic granulomatous disease, Immune system, Immunodeficiency and Cell biology. His is involved in several facets of Immunology study, as is seen by his studies on Inflammation, Autoimmunity, Immunopathology, Chemokine and Interleukin. His Chronic granulomatous disease study combines topics in areas such as Mutation, Phagocyte, Internal medicine, Digital polymerase chain reaction and Allele.
His Immune system research includes themes of Tumor necrosis factor alpha, Epithelium, Immunoglobulin E and Keratinocyte. He has researched Immunodeficiency in several fields, including Immune dysregulation, Antibody and Cancer research. His Cell biology research focuses on subjects like T cell, which are linked to Cytokine, Autoimmune disease and Phosphorylation.
His primary areas of investigation include Immunology, Chronic granulomatous disease, Haematopoiesis, Progenitor cell and Immunopathology. Immunology is represented through his Immune system, Autoimmunity, CXCL9, Whole blood and Immunodeficiency research. Douglas B. Kuhns interconnects Allele, Compound heterozygosity, Candida albicans, Carrier state and Dihydrorhodamine 123 in the investigation of issues within Chronic granulomatous disease.
His studies in Haematopoiesis integrate themes in fields like Myeloid, Cancer research, Myeloid leukemia and Leukemia. His Progenitor cell research includes themes of CD34, CD33, Immunity and Immunotherapy. His Immunopathology study incorporates themes from Autoantibody, Immune tolerance, Lung, Pneumonitis and Pulmonary function testing.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
STAT3 Mutations in the Hyper-IgE Syndrome
Steven M. Holland;Frank R. DeLeo;Houda Z. Elloumi;Amy P. Hsu.
The New England Journal of Medicine (2007)
Residual NADPH oxidase and survival in chronic granulomatous disease.
Douglas B. Kuhns;W. Gregory Alvord;Theo Heller;Jordan J. Feld.
The New England Journal of Medicine (2010)
Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.
Ji-Liang Gao;D. B. Kuhns;H. L. Tiffany;D. Mcdermott.
Journal of Experimental Medicine (1993)
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
Amy P. Hsu;Elizabeth P. Sampaio;Javed Khan;Katherine R. Calvo.
Treatment of refractory disseminated nontuberculous mycobacterial infection with interferon gamma. A preliminary report.
Steven M. Holland;Eli M. Eisenstein;Douglas B. Kuhns;Maria L. Turner.
The New England Journal of Medicine (1994)
Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections
Andrei E. Medvedev;Arnd Lentschat;Arnd Lentschat;Douglas B. Kuhns;Jorge C.G. Blanco.
Journal of Experimental Medicine (2003)
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
Donald C. Vinh;Smita Y. Patel;Gulbu Uzel;Victoria L. Anderson.
A Hypermorphic Missense Mutation in PLCG2, Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency
Qing Zhou;Geun-Shik Lee;Geun-Shik Lee;Jillian Brady;Shrimati Datta.
American Journal of Human Genetics (2012)
Common Severe Infections in Chronic Granulomatous Disease
Beatriz E. Marciano;Christine Spalding;Alan Fitzgerald;Daphne Mann.
Clinical Infectious Diseases (2015)
Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis
Elizabeth P. Sampaio;Elizabeth P. Sampaio;Amy P. Hsu;Joseph Pechacek;Hannelore I. Bax;Hannelore I. Bax.
The Journal of Allergy and Clinical Immunology (2013)
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