What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Internal medicine
Douglas B. Kuhns mostly deals with Immunology, Mutation, Chronic granulomatous disease, Molecular biology and Leukemia.
His Immunology research is multidisciplinary, incorporating perspectives in Missense mutation and Genetic enhancement.
His research integrates issues of Protein inhibitor of activated STAT, Microbiology, Transactivation, Disseminated coccidioidomycosis and STAT1 in his study of Mutation.
His study focuses on the intersection of Chronic granulomatous disease and fields such as NADPH oxidase with connections in the field of Gene, X chromosome and Frameshift mutation.
His Molecular biology research integrates issues from Interleukin 18, CXCL2, CCR1 and Signal transduction, Kinase activity.
The study incorporates disciplines such as GATA2 Deficiency, Cancer research and Monocytopenia, MonoMAC in addition to Leukemia.
His most cited work include:
- STAT3 Mutations in the Hyper-IgE Syndrome (894 citations)
- Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome (428 citations)
- Residual NADPH oxidase and survival in chronic granulomatous disease. (363 citations)
What are the main themes of his work throughout his whole career to date?
Douglas B. Kuhns spends much of his time researching Immunology, Chronic granulomatous disease, Molecular biology, Internal medicine and Immunodeficiency.
His work in Immunology addresses issues such as Mutation, which are connected to fields such as Genotype.
Douglas B. Kuhns combines subjects such as NADPH oxidase, CYBB, Inflammatory bowel disease, Phagocyte and Gene with his study of Chronic granulomatous disease.
His Molecular biology study incorporates themes from Kinase, Interleukin 8 and Exon.
His Internal medicine study also includes fields such as
-
Gastrointestinal disease and Pathology most often made with reference to Gastroenterology,
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Endocrinology together with Lactoferrin.
His research on Immunodeficiency also deals with topics like
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Colitis that connect with fields like CD18 and Leukocyte adhesion deficiency-1,
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Immune dysregulation which intersects with area such as Phenotype.
He most often published in these fields:
- Immunology (60.00%)
- Chronic granulomatous disease (36.36%)
- Molecular biology (20.00%)
What were the highlights of his more recent work (between 2017-2021)?
- Immunology (60.00%)
- Chronic granulomatous disease (36.36%)
- Immune system (9.09%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Immunology, Chronic granulomatous disease, Immune system, Immunodeficiency and Cell biology.
His is involved in several facets of Immunology study, as is seen by his studies on Inflammation, Autoimmunity, Immunopathology, Chemokine and Interleukin.
His Chronic granulomatous disease study combines topics in areas such as Mutation, Phagocyte, Internal medicine, Digital polymerase chain reaction and Allele.
His Immune system research includes themes of Tumor necrosis factor alpha, Epithelium, Immunoglobulin E and Keratinocyte.
He has researched Immunodeficiency in several fields, including Immune dysregulation, Antibody and Cancer research.
His Cell biology research focuses on subjects like T cell, which are linked to Cytokine, Autoimmune disease and Phosphorylation.
Between 2017 and 2021, his most popular works were:
- Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia (141 citations)
- X-linked carriers of chronic granulomatous disease: Illness, lyonization, and stability. (78 citations)
- Lentiviral gene therapy for X-linked chronic granulomatous disease. (53 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Internal medicine
His primary areas of investigation include Immunology, Chronic granulomatous disease, Haematopoiesis, Progenitor cell and Immunopathology.
Immunology is represented through his Immune system, Autoimmunity, CXCL9, Whole blood and Immunodeficiency research.
Douglas B. Kuhns interconnects Allele, Compound heterozygosity, Candida albicans, Carrier state and Dihydrorhodamine 123 in the investigation of issues within Chronic granulomatous disease.
His studies in Haematopoiesis integrate themes in fields like Myeloid, Cancer research, Myeloid leukemia and Leukemia.
His Progenitor cell research includes themes of CD34, CD33, Immunity and Immunotherapy.
His Immunopathology study incorporates themes from Autoantibody, Immune tolerance, Lung, Pneumonitis and Pulmonary function testing.
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