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Molecular Biology

D-Index
72
Citations
18521
World Ranking
1320
National Ranking
99

Overview

Nicholas Coleman is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology. Within these areas, the scientist has concentrated on specialized subfields such as molecular biology, cancer research, surgery, pulmonary and respiratory medicine, and oncology.

The core themes of their scientific investigations include:

  • Testicular diseases and treatments
  • Sarcoma diagnosis and treatment
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Renal and related cancers
  • Glioma diagnosis and treatment
  • Cancer genomics and diagnostics

Several of their recent publications illustrate the scope of their work. These include:

  • Circulating MicroRNAs, the Next-Generation Serum Biomarkers in Testicular Germ Cell Tumours: A Systematic Review (2021, European Urology)
  • Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells (2022, Nature Communications)
  • Single cell derived mRNA signals across human kidney tumors (2021, Nature Communications)
  • Real-World Application of Pre-Orchiectomy miR-371a-3p Test in Testicular Germ Cell Tumor Management (2020, The Journal of Urology)
  • Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection (2021, European Urology Open Science)

Frequent co-authors in their research include:

  • Matthew J. Murray
  • Cinzia G. Scarpini
  • James F. Amatruda
  • John T. Lafin
  • Aditya Bagrodia

Publication venues where Nicholas Coleman has contributed multiple works feature:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • The Journal of Urology
  • Neuro-Oncology
  • Nature Communications

Best Publications

  • Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

    Matthew D. Young;Thomas J. Mitchell;Thomas J. Mitchell;Thomas J. Mitchell;Felipe A. Vieira Braga;Maxine G. B. Tran

  • The landscape of somatic mutation in normal colorectal epithelial cells

    Henry Lee-Six;Sigurgeir Olafsson;Peter Ellis;Robert J Osborne

  • Minichromosome maintenance proteins as biological markers of dysplasia and malignancy.

    Alex Freeman;Lesley S. Morris;Anthony D. Mills;Kai Stoeber

  • Improved cervical smear assessment using antibodies against proteins that regulate DNA replication.

    Gareth H. Williams;Piotr Romanowski;Lesley Morris;Mark Madine

  • DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans.

    Stefan Pöhlmann;Elizabeth J. Soilleux;Frédéric Baribaud;George J. Leslie

  • Spatiotemporal immune zonation of the human kidney

    Benjamin J. Stewart;Benjamin J. Stewart;Benjamin J. Stewart;John R. Ferdinand;Matthew D. Young;Thomas J. Mitchell;Thomas J. Mitchell;Thomas J. Mitchell

  • Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation

    Esther Unitt;Aileen Marshall;William Gelson;Simon M. Rushbrook

  • What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast

    Cheryl Q.E. Lee;Lucy Gardner;Margherita Turco;Nancy Zhao

  • FUS/ERG gene fusions in Ewing's tumors.

    Danielle C. Shing;Dominic J. McMullan;Paul Roberts;Kim Smith

  • Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets.

    Roger D. Palmer;Matthew J. Murray;Harpreet K. Saini;Stijn van Dongen

  • Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease.

    Aloysious Aravinthan;Cinzia Scarpini;Phaedra Tachtatzis;Suman Verma

  • Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes.

    Mark R. Pett;William O. F. Alazawi;Ian Roberts;Sally Dowen

  • cis Expression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor

    Benhur Lee;George Leslie;Elizabeth Soilleux;Una O'Doherty

  • Characterization of Events during the Late Stages of HPV16 Infection in Vivo Using High-Affinity Synthetic Fabs to E4

    John Doorbar;Charmaine Foo;Nick Coleman;Liz Medcalf

  • Control of DNA replication and its potential clinical exploitation

    Michael A. Gonzalez;Kiku-e K. Tachibana;Ronald A. Laskey;Nicholas Coleman

  • Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response.

    Mark R. Pett;M. Trent Herdman;Roger D. Palmer;Giles S. H. Yeo

  • Minichromosome Maintenance Protein 2 Is a Strong Independent Prognostic Marker in Breast Cancer

    Michael A. Gonzalez;Sarah E. Pinder;Grace Callagy;Sarah L. Vowler

  • Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool.

    R Justin Davies;Alex Freeman;Lesley S Morris;Sheila Bingham

  • Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV

    Elizabeth J. Soilleux;Lesley S. Morris;Benhur Lee;Stefan Pöhlmann

  • Pathogenesis of human papillomavirus-associated mucosal disease

    Unknown

Frequent Co-Authors

Margaret Stanley
Margaret Stanley University of Cambridge
Ronald A. Laskey
Ronald A. Laskey University of Cambridge
Graeme J. M. Alexander
Graeme J. M. Alexander University College London
Sam Behjati
Sam Behjati Wellcome Sanger Institute
Anton J. Enright
Anton J. Enright University of Cambridge
Ian Roberts
Ian Roberts University of Cambridge
Neil J. Sebire
Neil J. Sebire Great Ormond Street Hospital
Muzlifah Haniffa
Muzlifah Haniffa Newcastle University
Rebecca C. Fitzgerald
Rebecca C. Fitzgerald University of Cambridge
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge

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