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Immunology

D-Index
91
Citations
36050
World Ranking
1025
National Ranking
37

Overview

Teunis B.H. Geijtenbeek is affiliated with VU University Medical Center in the Netherlands and has contributed extensively to research in medicine, particularly focusing on immunology and microbiology. Their work spans multiple subfields including immunology, infectious diseases, epidemiology, molecular biology, and virology.

The scientist's recent publications cover diverse topics such as the immune response to viral infections, COVID-19 clinical features, and microbial interactions with the immune system. Notable papers include:

  • "Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity" (2020, Science)
  • "Clinical features and prognostic factors in Covid-19: A prospective cohort study" (2021, EBioMedicine)
  • "Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients" (2021, Intensive Care Medicine)
  • "Vaginal dysbiosis associated-bacteria Megasphaera elsdenii and Prevotella timonensis induce immune activation via dendritic cells" (2020, Journal of Reproductive Immunology)
  • "Infection and transmission of SARS-CoV-2 depend on heparan sulfate proteoglycans" (2021, The EMBO Journal)

The areas of research focus include:

  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Interferon and Immune Responses
  • HIV/AIDS Research and Interventions

Frequent collaborators in their research network are:

  • Diederik van de Beek
  • Neeltje A. Kootstra
  • Lieuwe D. J. Bos
  • Alexander P. J. Vlaar
  • Michiel A. van Agtmael

The scientist's publications predominantly appear in journals such as:

  • Frontiers in Immunology
  • Scientific Reports
  • European Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • EBioMedicine

Overall, their work contributes to the understanding of immune mechanisms in infectious diseases, with a strong emphasis on responses to HIV and SARS-CoV-2 infections, as well as clinical research related to COVID-19. The interdisciplinary approach integrates molecular and clinical data to explore infection dynamics and immune system interactions.

Best Publications

  • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

    T.B.H. Geijtenbeek;D.S. Kwon;R. Torensma;S.J. van Vliet

  • Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses

    T.B.H. Geijtenbeek;R. Torensma;S.J. van Vliet;G.C.F. van Duijnhoven

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Signalling through C-type lectin receptors: shaping immune responses

    Teunis B. H. Geijtenbeek;Sonja I. Gringhuis

  • Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function

    Teunis B.H. Geijtenbeek;Sandra J. van Vliet;Estella A. Koppel;Marta Sanchez-Hernandez

  • DC-SIGN: escape mechanism for pathogens

    Yvette van Kooyk;Teunis B H Geijtenbeek

  • The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells.

    Anneke Engering;Teunis B. H. Geijtenbeek;Sandra J. van Vliet;Mietske Wijers

  • C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB

    Sonja I. Gringhuis;Jeroen den Dunnen;Manja Litjens;Bert van het Hof

  • Langerin is a natural barrier to HIV-1 transmission by Langerhans cells.

    Lot de Witte;Alexey Nabatov;Marjorie Pion;Donna Fluitsma

  • SELF- AND NONSELF-RECOGNITION BY C-TYPE LECTINS ON DENDRITIC CELLS

    Teunis B H Geijtenbeek;Sandra J van Vliet;Anneke Engering;Bert A 't Hart

  • Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-|[kappa]|B activation through Raf-1 and Syk

    Sonja I Gringhuis;Jeroen den Dunnen;Manja Litjens;Michiel van der Vlist

  • Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

    Sonja I Gringhuis;Tanja M Kaptein;Brigitte A Wevers;Bart Theelen

  • Cutting Edge: Carbohydrate Profiling Identifies New Pathogens That Interact with Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells

    Ben J. Appelmelk;Irma van Die;Sandra J. van Vliet;Christina M. J. E. Vandenbroucke-Grauls

  • Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori.

    Sonja I Gringhuis;Sonja I Gringhuis;Jeroen den Dunnen;Jeroen den Dunnen;Manja Litjens;Michiel van der Vlist;Michiel van der Vlist

  • Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN

    Klaas P.J.M. van Gisbergen;Marta Sanchez-Hernandez;Teunis B.H. Geijtenbeek;Yvette van Kooyk

  • The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

    Irma van Die;Sandra J van Vliet;A Kwame Nyame;Richard D Cummings

  • A Dendritic Cell–Specific Intercellular Adhesion Molecule 3–Grabbing Nonintegrin (Dc-Sign)–Related Protein Is Highly Expressed on Human Liver Sinusoidal Endothelial Cells and Promotes HIV-1 Infection

    Arman A Bashirova;Teunis B.H. Geijtenbeek;Gerard C.F. van Duijnhoven;Sandra J. van Vliet

  • Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy.

    Ulrike Kämmerer;Andreas O. Eggert;Michaela Kapp;Alexander D. McLellan

  • FANTOM5 CAGE profiles of human and mouse samples

    Shuhei Noguchi;Takahiro Arakawa;Shiro Fukuda;Masaaki Furuno

  • HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

    Sonja I Gringhuis;Sonja I Gringhuis;Michiel van der Vlist;Michiel van der Vlist;Linda M van den Berg;Linda M van den Berg;Jeroen den Dunnen;Jeroen den Dunnen

  • Predominant infection of CD150+ lymphocytes and dendritic cells during measles virus infection of macaques.

    Rik L de Swart;Martin Ludlow;Lot de Witte;Yusuke Yanagi

Frequent Co-Authors

Yvette van Kooyk
Yvette van Kooyk Vrije Universiteit Amsterdam
Sandra J. van Vliet
Sandra J. van Vliet University of Amsterdam
Ben J. Appelmelk
Ben J. Appelmelk Amsterdam University Medical Centers
Irma van Die
Irma van Die VU University Medical Center
Carl G. Figdor
Carl G. Figdor Radboud University
William A. Paxton
William A. Paxton University of Liverpool
Georgios Pollakis
Georgios Pollakis University of Liverpool
Tom van der Poll
Tom van der Poll University of Amsterdam
Christina M. J. E. Vandenbroucke-Grauls
Christina M. J. E. Vandenbroucke-Grauls Vrije Universiteit Amsterdam
Joppe W. Hovius
Joppe W. Hovius University of Amsterdam

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