World's Best Scientists 2026 revealed!
Thomas W. Holstein

Thomas W. Holstein

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
11388
World Ranking
16074
National Ranking
1125

Overview

Thomas W. Holstein is affiliated with Heidelberg University in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, as well as earth and planetary sciences. Within these fields, Holstein has contributed extensively to paleontology, molecular biology, and cell biology, with additional work related to global and planetary change and environmental chemistry.

The scientist's main research topics include marine invertebrate physiology and ecology, planarian biology and electrostimulation, marine ecology and invasive species, Hippo pathway signaling and YAP/TAZ, marine toxins and detection methods, cellular mechanics and interactions, and protist diversity and phylogeny.

Frequent publication venues where Holstein's work appears include bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Cells and Development, iScience, and eLife.

Holstein's recent published papers include:

  • The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling, 2022, Developmental Biology
  • The Hydra stem cell system - Revisited, 2023, Cells and Development

Other relevant papers in the same field, co-authored or related, include:

  • The origin and evolution of Wnt signalling, 2024, Nature Reviews Genetics
  • Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling, 2022, Proceedings of the National Academy of Sciences
  • The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra, 2021, BMC Biology

Holstein's frequent collaborators consist of Suat Özbek, Anja Tursch, Moritz Mercker, Anna Marciniak-Czochra, and Robert E. Steele. These collaborations reflect a multidisciplinary approach in developmental biology and molecular signaling.

Best Publications

  • The dynamic genome of Hydra

    Jarrod A. Chapman;Ewen F. Kirkness;Oleg Simakov;Oleg Simakov;Steven E. Hampson

  • Unexpected complexity of the Wnt gene family in a sea anemone

    Arne Kusserow;Kevin Pang;Carsten Sturm;Martina Hrouda

  • WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra

    Bert Hobmayer;Fabian Rentzsch;Kerstin Kuhn;Christoph M. Happel

  • The deep evolution of metazoan microRNAs

    Benjamin M. Wheeler;Alysha M. Heimberg;Vanessa N. Moy;Erik A. Sperling

  • Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

    Ulrich Technau;Stephen Rudd;Peter Maxwell;Paul M. Gordon

  • An Ultrahigh-Speed Analysis of Exocytosis: Nematocyst Discharge

    T Holstein;P Tardent

  • Multiple Wnts are involved in Hydra organizer formation and regeneration

    Tobias Lengfeld;Hiroshi Watanabe;Oleg Simakov;Dirk Lindgens

  • Cnidarians: An evolutionarily conserved model system for regeneration?

    T.W. Holstein;E. Hobmayer;E. Hobmayer;U. Technau

  • The Evolution of the Wnt Pathway

    Thomas W. Holstein

  • The Wnt code: cnidarians signal the way

    C Guder;I Philipp;T Lengfeld;H Watanabe

  • Cnidarians and the evolutionary origin of the nervous system

    Hiroshi Watanabe;Toshitaka Fujisawa;Thomas W. Holstein

  • Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response

    Kyle A. Gurley;Sarah A. Elliott;Oleg Simakov;Heiko A. Schmidt

  • Nanosecond-scale kinetics of nematocyst discharge.

    Timm Nüchter;Martin Benoit;Ulrike Engel;Ulrike Engel;Suat Özbek

  • Pattern of epithelial cell cycling in hydra.

    Thomas W. Holstein;Engelbert Hobmayer;Charles N. David

  • Wnt/β-Catenin and noncanonical Wnt signaling interact in tissue evagination in the simple eumetazoan Hydra

    Isabelle Philipp;Roland Aufschnaiter;Suat Özbek;Stefanie Pontasch

  • An ancient Wnt-Dickkopf antagonism in Hydra.

    Corina Guder;Corina Guder;Sonia Pinho;Tanju G. Nacak;Tanju G. Nacak;Heiko A. Schmidt

  • Asymmetric expression of the BMP antagonists chordin and gremlin in the sea anemone Nematostella vectensis: implications for the evolution of axial patterning.

    Fabian Rentzsch;Roman Anton;Roman Anton;Michael Saina;Matthias Hammerschmidt

  • Parameters of self-organization in Hydra aggregates

    Ulrich Technau;Christoph Cramer von Laue;Fabian Rentzsch;Susanne Luft

  • Evolution of complex structures: minicollagens shape the cnidarian nematocyst.

    Charles N. David;Suat Özbek;Patrizia Adamczyk;Sebastian Meier

  • Evolution of Developmental Control Mechanisms Multiple Wnts are involved in Hydra organizer formation and regeneration

    Tobias Lengfeld;Hiroshi Watanabe;Oleg Simakov;Dirk Lindgens

Frequent Co-Authors

Charles N. David
Charles N. David Ludwig-Maximilians-Universität München
Ulrich Technau
Ulrich Technau University of Vienna
Jürgen Engel
Jürgen Engel University of Basel
Hans R. Bode
Hans R. Bode University of California, Irvine
Sebastian Meier
Sebastian Meier Technical University of Denmark
Takashi Gojobori
Takashi Gojobori King Abdullah University of Science and Technology
Thomas C. G. Bosch
Thomas C. G. Bosch Kiel University
Stephan Grzesiek
Stephan Grzesiek University of Basel
Robert Steele
Robert Steele University of California, Irvine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Earning a degree in Biology or Biochemistry opens doors to a wide range of online programs and career trajectories in the health and science sectors. Graduates often expand their qualifications with specialized degrees that align with growing job opportunities in healthcare, nutrition, and management.

For those interested in food sciences and wellness, consider an online dietitian degree, which can lead to careers in clinical nutrition, community health, or research. If you aim to pursue healthcare administration at a high level, explore top online mha programs that are cahme accredited, widely respected by healthcare employers.

Advanced nursing professionals might consider flexible dnp online no clinicals programs, ideal for those balancing work and study commitments. For those aiming at top leadership or academic roles in healthcare, online doctoral programs healthcare administration are a strong choice.

With the variety of online options now available, you can tailor your education and career pathway to suit your goals in biology, biochemistry, and intersecting health fields.

Best Scientists Citing Thomas W. Holstein

Trending Scientists

Recently Published Articles