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Genetics

D-Index
65
Citations
14109
World Ranking
2709
National Ranking
1189

Research.com Recognitions

  • 1994 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert Steele is affiliated with the University of California, Irvine in the United States. Their research extensively covers the intersection of biochemistry, genetics, molecular biology, and medicine, with a particular focus on molecular biology, cancer research, immunology, infectious diseases, and dermatology.

Their work addresses several key topics, including:

  • Extracellular vesicles in disease
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • COVID-19 clinical research studies
  • Dermatological and COVID-19 studies
  • Inflammasome and immune disorders
  • RNA research and splicing

Steele's research has been published in various scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Hepatology
  • Journal of Biological Chemistry
  • International Journal of Molecular Sciences
  • mBio

Recent notable papers include:

  • Exosomes from COVID-19 Patients Carry Tenascin-C and Fibrinogen-β in Triggering Inflammatory Signals in Cells of Distant Organ, 2021, International Journal of Molecular Sciences
  • Inhibition of Long Noncoding RNA Linc-Pint by Hepatitis C Virus in Infected Hepatocytes Enhances Lipogenesis, 2020, Hepatology
  • Circulatory Exosomes from COVID-19 Patients Trigger NLRP3 Inflammasome in Endothelial Cells, 2022, mBio
  • Long non-coding RNA ELDR enhances oral cancer growth by promoting ILF 3-cyclin E1 signaling, 2020, EMBO Reports
  • Momordicine-I, a Bitter Melon Bioactive Metabolite, Displays Anti-Tumor Activity in Head and Neck Cancer Involving c-Met and Downstream Signaling, 2021, Cancers

Steele has collaborated frequently with several co-authors, notably Ratna B. Ray, Subhayan Sur, Mousumi Khatun, T. Scott Isbell, and Ranjit Ray.

In 1994, Steele was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

    Nicholas H. Putnam;Mansi Srivastava;Uffe Hellsten;Bill Dirks

  • The dynamic genome of Hydra

    Jarrod A. Chapman;Ewen F. Kirkness;Oleg Simakov;Oleg Simakov;Steven E. Hampson

  • Transcriptional Repression of p53 Promoter by Hepatitis C Virus Core Protein

    Ratna B. Ray;Robert Steele;Keith Meyer;Ranjit Ray

  • The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes

    Yanjie Liu;Rita Tewari;Rita Tewari;Jue Ning;Andrew M. Blagborough;Andrew M. Blagborough

  • Hepatitis C Virus NS5A Physically Associates with p53 and Regulates p21/waf1 Gene Expression in a p53-Dependent Manner

    Mainak Majumder;Asish K. Ghosh;Robert Steele;Ranjit Ray

  • Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein

    R. B. Ray;L. M. Lagging;K. Meyer;R. Steele

  • Inhibition of Tumor Necrosis Factor (TNF-α)-mediated Apoptosis by Hepatitis C Virus Core Protein *

    Ratna B. Ray;Keith Meyer;Robert Steele;Anju Shrivastava

  • Evolutionary crossroads in developmental biology: Cnidaria

    Ulrich Technau;Robert E. Steele

  • Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growth.

    Asish K. Ghosh;Robert Steele;Keith Meyer;Ranjit Ray

  • Thermotolerance and synthesis of heat shock proteins: these responses are present in Hydra attenuata but absent in Hydra oligactis

    Thomas C. G. Bosch;Susan M. Krylow;Hans R. Bode;Robert E. Steele

  • Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes.

    Shubham Shrivastava;Amit Raychoudhuri;Robert Steele;Ranjit Ray

  • Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements

    D Chourrout;F Delsuc;P Chourrout;R B Edvardsen

  • Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity

    Ratna B Ray;Robert Steele;Keith Meyer;Ranjit Ray

  • Budhead,a Fork Head/HNF-3 Homologue, Is Expressed during Axis Formation and Head Specification in Hydra☆

    Daniel E. Martinez;Daniel E. Martinez;Marie-Luise Dirksen;Patricia M. Bode;Milan Jamrich

  • Evolutionary Differences in Glycosaminoglycan Fine Structure Detected by Quantitative Glycan Reductive Isotope Labeling

    Roger Lawrence;Sara K. Olson;Robert E. Steele;Lianchun Wang

  • Expression of Cnox-2, a HOM/HOX homeobox gene in hydra, is correlated with axial pattern formation.

    M.A. Shenk;H.R. Bode;R.E. Steele

  • Developmental Signaling in Hydra: What Does It Take to Build a “Simple” Animal?

    Robert E. Steele

  • Hepatitis C Virus Upregulates Beclin1 for Induction of Autophagy and Activates mTOR Signaling

    Shubham Shrivastava;Joydip Bhanja Chowdhury;Robert Steele;Ranjit Ray

  • PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells

    Celina E. Juliano;Adrian Reich;Na Liu;Jessica Götzfried

  • ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

    Amit Raychoudhuri;Shubham Shrivastava;Robert Steele;Hangeun Kim

Frequent Co-Authors

Ratna B. Ray
Ratna B. Ray Saint Louis University
Ranjit Ray
Ranjit Ray Saint Louis University
Ulrich Technau
Ulrich Technau University of Vienna
Hans R. Bode
Hans R. Bode University of California, Irvine
Helen McNeill
Helen McNeill Washington University in St. Louis
Daniel S. Rokhsar
Daniel S. Rokhsar University of California, Berkeley
Adrian M. Di Bisceglie
Adrian M. Di Bisceglie Saint Louis University
Thomas W. Holstein
Thomas W. Holstein Heidelberg University
Charles N. David
Charles N. David Ludwig-Maximilians-Universität München
Haifan Lin
Haifan Lin Yale University

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