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Chemistry

D-Index
47
Citations
11286
World Ranking
15485
National Ranking
619

Overview

J. Carlos Menéndez is affiliated with the Complutense University of Madrid in Spain. Their body of research spans multiple disciplines including chemistry, medicine, and biochemistry, genetics, and molecular biology. Within these broad fields, their work predominantly focuses on organic chemistry, molecular biology, pharmacology, oncology, and materials chemistry.

The main topics addressed in Menéndez's research include synthesis and biological evaluation, multicomponent synthesis of heterocycles, cholinesterase and neurodegenerative diseases, synthesis and biological activity, chemical synthesis and analysis, Alzheimer's disease research and treatments, and the study of genomics, phytochemicals, and oxidative stress.

Menéndez has published numerous articles in a variety of scientific journals. Frequent publication venues include:

  • Antioxidants
  • Molecules
  • European Journal of Medicinal Chemistry
  • The Journal of Organic Chemistry
  • Molbank

Notable recent papers authored or co-authored by Menéndez include:

  • "Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects" (2023, Pharmaceutics)
  • "NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases" (2020, Biomolecules)
  • "Quinones as Neuroprotective Agents" (2023, Antioxidants)
  • "Multicomponent Reactions for the Synthesis of Active Pharmaceutical Ingredients" (2022, Pharmaceuticals)
  • "Enantioselective catalytic Povarov reactions" (2021, Organic & Biomolecular Chemistry)

Menéndez has frequently collaborated with several co-authors, including:

  • Carmen Avendaño
  • Ángel Cores
  • Juan F. González
  • José Clerigué
  • Mercedes Villacampa

The research themes covered illustrate a concentration on the chemical synthesis and biological evaluation of pharmacologically relevant compounds. This includes a significant interest in neurodegenerative disease targets and methodologies to enhance drug bioavailability and neuroprotection.

Best Publications

  • Advances in the chemistry of tetrahydroquinolines.

    Vellaisamy Sridharan;Padmakar A. Suryavanshi;J. Carlos Menéndez

  • Multicomponent reactions for the synthesis of pyrroles

    Verónica Estévez;Mercedes Villacampa;J. Carlos Menéndez

  • Recent advances in the synthesis of pyrroles by multicomponent reactions

    Verónica Estévez;Mercedes Villacampa;J. Carlos Menéndez

  • Medicinal Chemistry of Anticancer Drugs

    Carmen Avendaño;J. Carlos Menéndez

  • Progress in the Chemistry of Tetrahydroquinolines.

    Isravel Muthukrishnan;Vellaisamy Sridharan;Vellaisamy Sridharan;J Carlos Menéndez

  • Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis

    Vellaisamy Sridharan;J Carlos Menéndez

  • Inhibitors of Multidrug resistance to antitumor agents (MDR)

    Carmen Avendaño;J Carlos Menéndez

  • Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience.

    Matteo Staderini;María Antonia Martín;Maria Laura Bolognesi;J. Carlos Menéndez

  • New synthetic applications of aryllead triacetates. N-arylation of azoles.

    Pilar Lopez-Alvarado;Carmen Avendano;J. Carlos Menendez

  • Domino reactions for the synthesis of bridged bicyclic frameworks: fast access to bicyclo[n.3.1]alkanes

    Miriam Ruiz;Pilar López-Alvarado;Giorgio Giorgi;J. Carlos Menéndez

  • Three-component access to pyrroles promoted by the CAN–silver nitrate system under high-speed vibration milling conditions: a generalization of the Hantzsch pyrrole synthesis

    Verónica Estévez;Mercedes Villacampa;J. Carlos Menéndez

  • Antimycobacterial activity of spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrids obtained by a three-component regio- and stereoselective 1,3-dipolar cycloaddition

    Stephen Michael Rajesh;Subbu Perumal;J. Carlos Menéndez;Perumal Yogeeswari

  • Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects

    Unknown

  • Cerium(IV) Ammonium Nitrate Is an Excellent, General Catalyst for the Friedländer and Friedländer−Borsche Quinoline Syntheses: Very Efficient Access to the Antitumor Alkaloid Luotonin A

    Vellaisamy Sridharan;Pascual Ribelles;Ma Teresa Ramos;J. Carlos Menéndez

  • Proline and its Derivatives as Organocatalysts for Multi- Component Reactions in Aqueous Media: Synergic Pathways to the Green Synthesis of Heterocycles

    B. S. Vachan;Muthu Karuppasamy;Perumal Vinoth;Sundaravel Vivek Kumar

  • Total synthesis of the ionophore antibiotic CP-61,405 (routiennocin)

    David Díez-Martin;Nikesh R. Kotecha;Steven V. Ley;Sergio Mantegani

  • A new three-component domino synthesis of 1,4-dihydropyridines

    Vellaisamy Sridharan;Paramasivan T. Perumal;Carmen Avendaño;J. Carlos Menéndez

  • Acid‐Free Synthesis of Carbazoles and Carbazolequinones by Intramolecular Pd‐Catalyzed, Microwave‐Assisted Oxidative Biaryl Coupling Reactions – Efficient Syntheses of Murrayafoline A, 2‐Methoxy‐3‐methylcarbazole, and Glycozolidine

    Vellaisamy Sridharan;M. Antonia Martín;J. Carlos Menéndez

  • L-Proline-catalysed sequential four-component “on water” protocol for the synthesis of structurally complex heterocyclic ortho-quinones

    Stephen Michael Rajesh;Balasubramanian Devi Bala;Subbu Perumal;J. Carlos Menéndez

  • Chemodivergent, multicomponent domino reactions in aqueous media: L-proline-catalyzed assembly of densely functionalized 4H-pyrano[2,3-c]pyrazoles and bispyrazolyl propanoates from simple, acyclic starting materials

    Pitchaimani Prasanna;Subbu Perumal;J. Carlos Menéndez

  • The Hantzsch Pyrrole Synthesis: Non-conventional Variations and Applications of a Neglected Classical Reaction

    Marco Leonardi;Verónica Estévez;Mercedes Villacampa;J. Carlos Menéndez

  • Brief Total Synthesis of the Cell Cycle Inhibitor Tryprostatin B and Related Preparation of Its Alanine Analogue

    Esmeralda Caballero;Carmen Avendaño;J Carlos Menéndez

  • New four-component reactions in water: a convergent approach to the metal-free synthesis of spiro[indoline/acenaphthylene-3,4′-pyrazolo[3,4-b]pyridine derivatives

    Kamaraj Balamurugan;Subbu Perumal;J. Carlos Menéndez

  • Microwave Assisted Organic Synthesis

    J. Carlos Menéndez

Frequent Co-Authors

Maria Laura Bolognesi
Maria Laura Bolognesi University of Bologna
Jean Rodriguez
Jean Rodriguez Aix-Marseille University
Giuseppe Legname
Giuseppe Legname International School for Advanced Studies
Paolo Carloni
Paolo Carloni Forschungszentrum Jülich
Hoong-Kun Fun
Hoong-Kun Fun Universiti Sains Malaysia
Tomas Tejero
Tomas Tejero University of Zaragoza
Pedro Merino
Pedro Merino University of Zaragoza
Dharmarajan Sriram
Dharmarajan Sriram Birla Institute of Technology and Science, Pilani
José M. Pingarrón
José M. Pingarrón Complutense University of Madrid
Manuela Bartolini
Manuela Bartolini University of Bologna

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