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Overview

Irma van Die is affiliated with VU University Medical Center in the Netherlands and has contributed to various research areas primarily within immunology, microbiology, medicine, and biochemistry.

The main fields of study in their work include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

They have focused on subfields such as immunology, molecular biology, organic chemistry, infectious diseases, and epidemiology.

The main topics addressed in their research encompass:

  • Glycosylation and Glycoproteins Research
  • Galectins and Cancer Biology
  • Carbohydrate Chemistry and Synthesis
  • SARS-CoV-2 and COVID-19 Research
  • Immunotherapy and Immune Responses
  • Respiratory viral infections research
  • Proteoglycans and glycosaminoglycans research

The recent academic output includes the following papers:

  • "SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Differential O- and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior" (2020), published in Frontiers in Oncology
  • "Identification and characterization of circulating immune complexes in IgA nephropathy" (2022), published in Science Advances
  • "Tumor cells express pauci- and oligomannosidic N-glycans in glycoproteins recognized by the mannose receptor (CD206)" (2021), published in Cellular and Molecular Life Sciences
  • "N-glycosylation of mannose receptor (CD206) regulates glycan binding by C-type lectin domains" (2022), published in Journal of Biological Chemistry

Frequent co-authors in their research collaborations include:

  • Kathrin Stavenhagen
  • Richard D. Cummings
  • Chao Gao
  • Lisa C. Laan
  • Jamie Heimburg-Molinaro

The publication venues frequently featuring their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Oncology
  • Science Advances
  • Cellular and Molecular Life Sciences
  • Journal of Biological Chemistry

Best Publications

  • Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

    Ola Blixt;Steve Head;Tony Mondala;Christopher Scanlan

  • Cutting Edge: Carbohydrate Profiling Identifies New Pathogens That Interact with Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells

    Ben J. Appelmelk;Irma van Die;Sandra J. van Vliet;Christina M. J. E. Vandenbroucke-Grauls

  • The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

    Irma van Die;Sandra J van Vliet;A Kwame Nyame;Richard D Cummings

  • Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation.

    Ellis van Liempt;Sandra J van Vliet;Anneke Engering;Juan Jesus García Vallejo

  • Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells

    Sandra J. van Vliet;Ellis van Liempt;Eirikur Saeland;Corlien A. Aarnoudse

  • Specificity of DC-SIGN for mannose- and fucose-containing glycans

    Ellis van Liempt;Christine M.C. Bank;Padmaja Mehta;Juan Jesús Garcı´a-Vallejo

  • A novel glycosulfopeptide binds to P-selectin and inhibits leukocyte adhesion to P-selectin.

    Anne Leppänen;Padmaja Mehta;Ying-Bin Ouyang;Tongzhong Ju

  • Glycan gimmickry by parasitic helminths: A strategy for modulating the host immune response?

    I.M. van Die;RD Cummings

  • LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition.

    Timo K. van den Berg;Henk Honing;Niels Franke;Alexandra van Remoortere

  • Various stages of Schistosoma express Lewisx, LacdiNAc, GalNAcβ1–4 (Fucα1–3)GlcNAc and GalNAcβ1–4(Fucα1–2Fucα1–3)GlcNAc carbohydrate epitopes: detection with monoclonal antibodies that are characterized by enzymatically synthesized neoglycoproteins

    Alexandra van Remoortere;Cornelis H.Hokke;Govert J.van Dam;Irma van Die

  • Cutting edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1)

    T K van den Berg;D Nath;H J Ziltener;D Vestweber

  • An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes.

    Hans Bakker;Gerard J. A. Rouwendal;Anton S. Karnoup;Dion E. A. Florack

  • Galactofuranose in eukaryotes: aspects of biosynthesis and functional impact

    Boris Tefsen;Arthur F.J. Ram;Irma van Die;Françoise H. Routier

  • Receptor Structure for F1C Fimbriae of Uropathogenic Escherichia coli

    A. Salam Khan;Bernhard Kniep;Tobias A. Oelschlaeger;Irma Van Die

  • Core α1→3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep

    Irma van Die;Veronique Gomord;Frans N.J. Kooyman;Timo K. van den Berg

  • Demonstration of glycosaminoglycans in Caenorhabditis elegans

    Shuhei Yamada;Irma Van Die;Dirk H. Van den Eijnden;Akiko Yokota

  • Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens

    Ellis Van Liempt;Anne Imberty;Christine M C Bank;Sandra J Van Vliet

  • Galectin-3 Modulates Immune and Inflammatory Responses during Helminthic Infection: Impact of Galectin-3 Deficiency on the Functions of Dendritic Cells

    Laetitia Breuilh;François Vanhoutte;François Vanhoutte;Josette Fontaine;Josette Fontaine;Caroline M. W. van Stijn

  • Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients

    Eirikur Saeland;Ana I. Belo;Sandra Mongera;Irma van Die

  • Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated.

    Elsenoor J. Klaver;Loes M. Kuijk;Lisa C. Laan;Helene Kringel

Frequent Co-Authors

Richard D. Cummings
Richard D. Cummings Harvard Medical School
Yvette van Kooyk
Yvette van Kooyk Vrije Universiteit Amsterdam
Sandra J. van Vliet
Sandra J. van Vliet University of Amsterdam
Rudolf Geyer
Rudolf Geyer University of Giessen
Manfred Wuhrer
Manfred Wuhrer Leiden University Medical Center
Juan J. Garcia-Vallejo
Juan J. Garcia-Vallejo University of Amsterdam
Dirk Bosch
Dirk Bosch Wageningen University & Research
Cornelis H. Hokke
Cornelis H. Hokke Leiden University Medical Center
Arthur F. J. Ram
Arthur F. J. Ram Leiden University
André M. Deelder
André M. Deelder Leiden University Medical Center

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