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Molecular Biology

D-Index
80
Citations
23889
World Ranking
997
National Ranking
75

Overview

Akihiro Umezawa is a researcher affiliated with the National Institutes of Health in the United States. Their work spans key areas within biochemistry, genetics, molecular biology, and medicine, where they have contributed extensively to advancing knowledge in these fields.

Their main research subfields include molecular biology, genetics, surgery, biomedical engineering, and reproductive medicine. The scope of their investigation encompasses diverse topics such as pluripotent stem cells research, CRISPR and genetic engineering, 3D printing in biomedical research, liver physiology and pathology, pancreatic function and diabetes, the reproductive system and pregnancy, and tissue engineering and regenerative medicine.

Their publication record documents contributions across multiple scientific venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Regenerative Therapy
  • Stem Cell Research & Therapy
  • Scientific Reports
  • Stem Cell Reports

Recent papers authored by Akihiro Umezawa include:

  • Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder, 2021, Stem Cell Research & Therapy
  • Application of Mesenchymal Stem Cell Therapy and Inner Ear Regeneration for Hearing Loss: A Review, 2020, International Journal of Molecular Sciences
  • Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors, 2020, Cell Reports
  • Six years' accomplishment of the Initiative on Rare and Undiagnosed Diseases: nationwide project in Japan to discover causes, mechanisms, and cures, 2022, Journal of Human Genetics
  • Cell-binding peptides on the material surface guide stem cell fate of adhesion, proliferation and differentiation, 2023, Journal of Materials Chemistry B

Collaborations have been an important aspect of their research activities. Frequent co-authors include:

  • Hidenori Akutsu
  • Tomoyuki Kawasaki
  • Masashi Toyoda
  • Mureo Kasahara
  • Saeko Akiyama

Akihiro Umezawa's work reflects a strong focus on stem cell biology and regenerative medicine, intersecting technologies like genetic engineering and 3D bioprinting that contribute to understanding and potentially treating a range of medical conditions. Their experience encompasses both fundamental biological insights and applied biomedical engineering approaches.

Best Publications

  • Cardiomyocytes can be generated from marrow stromal cells in vitro

    Shinji Makino;Keiichi Fukuda;Shunichirou Miyoshi;Fusako Konishi

  • Physical cues of biomaterials guide stem cell differentiation fate.

    Akon Higuchi;Akon Higuchi;Qing Dong Ling;Yung Chang;Shih Tien Hsu

  • Brain from bone: efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent.

    Jun Kohyama;Hitoshi Abe;Takuya Shimazaki;Takuya Shimazaki;Amane Koizumi

  • In vivo cardiovasculogenesis by direct injection of isolated adult mesenchymal stem cells

    Satoshi Gojo;Noriko Gojo;Yukiji Takeda;Taisuke Mori

  • Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin

    Syuzo Kaneko;Roberto Bonasio;Ricardo Saldaña-Meyer;Takahaki Yoshida

  • Novel Cardiac Precursor‐Like Cells from Human Menstrual Blood‐Derived Mesenchymal Cells

    Naoko Hida;Naoko Hida;Nobuhiro Nishiyama;Shunichiro Miyoshi;Shinichiro Kira

  • Bone Marrow–Derived Regenerated Cardiomyocytes (CMG Cells) Express Functional Adrenergic and Muscarinic Receptors

    Daihiko Hakuno;Keiichi Fukuda;Shinji Makino;Fusako Konishi

  • DNA methylation dynamics in human induced pluripotent stem cells over time.

    Koichiro Nishino;Masashi Toyoda;Mayu Yamazaki-Inoue;Yoshihiro Fukawatase

  • Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress.

    Seiji Inoshita;Kohsuke Takeda;Takiko Hatai;Yoshio Terada

  • IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

    Weidong Zhu;Ichiro Shiojima;Yuzuru Ito;Zhi Li

  • Human genetic variation database, a reference database of genetic variations in the Japanese population.

    Koichiro Higasa;Noriko Miyake;Jun Yoshimura;Kohji Okamura

  • Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularization.

    Kazuhiro Suzuki;Ruowen Sun;Ruowen Sun;Makoto Origuchi;Masahiko Kanehira

  • Synovial fluid-derived mesenchymal stem cells increase after intra-articular ligament injury in humans.

    T. Morito;T. Muneta;K. Hara;Y.-J. Ju

  • Menstrual blood-derived cells confer human dystrophin expression in the murine model of Duchenne muscular dystrophy via cell fusion and myogenic transdifferentiation.

    Chang-Hao Cui;Taro Uyama;Kenji Miyado;Masanori Terai

  • Glycome Diagnosis of Human Induced Pluripotent Stem Cells Using Lectin Microarray

    Hiroaki Tateno;Masashi Toyota;Shigeru Saito;Yasuko Onuma

  • Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles.

    Yuko Segawa;Takeshi Muneta;Hatsune Makino;Akimoto Nimura

  • Production of Functional Classical Brown Adipocytes from Human Pluripotent Stem Cells using Specific Hemopoietin Cocktail without Gene Transfer

    Miwako Nishio;Takeshi Yoneshiro;Masako Nakahara;Shinnosuke Suzuki

  • Transcriptome analysis of mouse stem cells and early embryos.

    Alexei A Sharov;Yulan Piao;Ryo Matoba;Dawood B Dudekula

  • Xenografted Human Amniotic Membrane–Derived Mesenchymal Stem Cells Are Immunologically Tolerated and Transdifferentiated Into Cardiomyocytes

    Hiroko Tsuji;Shunichiro Miyoshi;Yukinori Ikegami;Naoko Hida

  • The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice

    Kenji Miyado;Keiichi Yoshida;Kazuo Yamagata;Keiichi Sakakibara

Frequent Co-Authors

Akon Higuchi
Akon Higuchi National Central University
Tohru Kiyono
Tohru Kiyono National Cancer Research Institute, UK
Satoshi Ogawa
Satoshi Ogawa Keio University
Kazuhiko Nakabayashi
Kazuhiko Nakabayashi National Center For Child Health and Development
Makoto Asashima
Makoto Asashima Teikyo University
Kenji Matsumoto
Kenji Matsumoto Izumi Municipal Hospital
Hirohisa Saito
Hirohisa Saito Juntendo University
Fumihiko Urano
Fumihiko Urano Washington University in St. Louis
Yung Chang
Yung Chang Chung Yuan Christian University
Michiie Sakamoto
Michiie Sakamoto Keio University

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