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Neuroscience

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92
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Medicine

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Overview

Tammie L.S. Benzinger is affiliated with Washington University in St. Louis, United States. Their research spans a broad range of studies primarily within the field of Medicine, with specific subfields including Physiology, Psychiatry and Mental Health, Radiology, Nuclear Medicine and Imaging, Cognitive Neuroscience, and Molecular Biology.

Their work extensively addresses topics related to dementia, cognitive impairment, and Alzheimer's disease research and treatments. Additional focus areas include functional brain connectivity studies, advanced neuroimaging techniques and applications, medical imaging techniques, advanced MRI techniques, and considerations of health, environment, and cognitive aging.

Significant recent publications include:

  • APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline (2020, Nature)
  • Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001 (2020, Journal of Clinical Oncology)
  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease (2020, Nature Medicine)
  • A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease (2021, Nature Medicine)
  • Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests (2024, Nature Medicine)

The scientist frequently collaborates with other researchers including John C. Morris, Brian A. Gordon, Randall J. Bateman, Eric McDade, and Carlos Cruchaga.

The main venues for their publications include:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine Scientific Meeting and Exhibition
  • Neurology
  • Brain

Best Publications

  • Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

    Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan

  • Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.

    Daniel A Nation;Melanie D Sweeney;Axel Montagne;Abhay P Sagare

  • The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET

    William E. Klunk;William E. Klunk;Robert A. Koeppe;Julie C. Price;Tammie L. Benzinger;Tammie L. Benzinger

  • APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

    Axel Montagne;Daniel A. Nation;Abhay P. Sagare;Giuseppe Barisano

  • Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

    Oliver Preische;Oliver Preische;Stephanie A. Schultz;Anja Apel;Anja Apel;Jens Kuhle

  • High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis.

    Suzanne E. Schindler;James G. Bollinger;Vitaliy Ovod;Kwasi G. Mawuenyega

  • Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

    Matthew R Brier;Brian Gordon;Karl Friedrichsen;John E McCarthy

  • Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.

    Paul D. Brown;Vinai Gondi;Stephanie Pugh;Wolfgang A. Tome

  • OASIS-3: Longitudinal Neuroimaging, Clinical, and Cognitive Dataset for Normal Aging and Alzheimer Disease

    Pamela J. LaMontagne;Tammie Ls. Benzinger;John C. Morris;Sarah Keefe

  • Loss of Intranetwork and Internetwork Resting State Functional Connections with Alzheimer's Disease Progression

    Mathew R. Brier;Jewell B. Thomas;Abraham Z. Snyder;Tammie L. Benzinger

  • Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

    Brian A Gordon;Tyler M Blazey;Yi Su;Amrita Hari-Raj

  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease.

    Nicolas R Barthélemy;Yan Li;Nelly Joseph-Mathurin;Brian A Gordon

  • Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis

    Vitaliy Ovod;Kara N. Ramsey;Kwasi G. Mawuenyega;Jim G. Bollinger

  • Tau Kinetics in Neurons and the Human Central Nervous System

    Chihiro Sato;Nicolas R. Barthélemy;Kwasi G. Mawuenyega;Bruce W. Patterson

  • White Matter Hyperintensities Are a Core Feature of Alzheimer's Disease: Evidence from the Dominantly Inherited Alzheimer Network

    Seonjoo Lee;Fawad Viqar;Fawad Viqar;Molly E. Zimmerman;Molly E. Zimmerman;Atul Narkhede

  • Propagating structure of Alzheimer’s β-amyloid(10–35) is parallel β-sheet with residues in exact register

    Tammie L. S. Benzinger;David M. Gregory;Timothy S. Burkoth;Hélène Miller-Auer

  • APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42.

    Yvette I Sheline;John C Morris;Abraham Z Snyder;Joseph L Price

  • Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease.

    Anne M. Fagan;Chengjie Xiong;Mateusz S. Jasielec;Randall J. Bateman

  • Regional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease

    Tammie L. S. Benzinger;Tyler Blazey;Clifford R. Jack;Robert A. Koeppe

  • Functional connectivity and graph theory in preclinical Alzheimer's disease

    Matthew R. Brier;Jewell B. Thomas;Anne M. Fagan;Jason Hassenstab

  • Radial Diffusivity Predicts Demyelination in ex-vivo Multiple Sclerosis Spinal Cords

    Eric C. Klawiter;Robert E. Schmidt;Kathryn Trinkaus;Hsiao-Fang Liang

  • White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

    Seonjoo Lee;Fawad Viqar;Molly E. Zimmerman;Atul Narkhede

Frequent Co-Authors

John C. Morris
John C. Morris Washington University in St. Louis
Randall J. Bateman
Randall J. Bateman Washington University in St. Louis
Anne M. Fagan
Anne M. Fagan Washington University in St. Louis
Beau M. Ances
Beau M. Ances Washington University in St. Louis
Peter R. Schofield
Peter R. Schofield Neuroscience Research Australia
David M. Holtzman
David M. Holtzman Washington University in St. Louis
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Stephen Salloway
Stephen Salloway Brown University
Daniel S. Marcus
Daniel S. Marcus Washington University in St. Louis
Jasmeer P. Chhatwal
Jasmeer P. Chhatwal Harvard University

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