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Immunology

D-Index
60
Citations
8977
World Ranking
3371
National Ranking
160

Overview

Alain Dessein is affiliated with Aix-Marseille University in France and has focused their research primarily in the field of Medicine.

Their research spans several subfields including Public Health, Environmental and Occupational Health, Epidemiology, Virology, Cell Biology, and Endocrinology, Diabetes and Metabolism. These areas reflect a broad engagement with both fundamental and applied medical sciences.

The main topics that Alain Dessein has contributed to include:

  • Liver Disease Diagnosis and Treatment
  • Malaria Research and Control
  • Mosquito-borne Diseases and Control
  • HIV Research and Treatment
  • Endoplasmic Reticulum Stress and Disease
  • Diet, Metabolism, and Disease
  • Nutrition and Health in Aging

Alain Dessein has published several papers that highlight their contributions across these topics, including:

  • Understanding Human Cerebral Malaria through a Blood Transcriptomic Signature: Evidences for Erythrocyte Alteration, Immune/Inflammatory Dysregulation, and Brain Dysfunction, 2020, Mediators of Inflammation
  • Clinical utility of polygenic risk scores for predicting NAFLD disorders, 2021, Journal of Hepatology
  • Genetic algorithms identify individuals with high risk of severe liver disease caused by schistosomes, 2020, Human Genetics
  • Correction to: Genetic algorithms identify individuals with high risk of severe liver disease caused by schistosomes, 2020, Human Genetics

Their frequent coauthors include:

  • Hélia Dessein
  • Nicolas Duflot
  • Audrey Romano
  • Christopher Opio
  • Carla Mola

Alain Dessein has published multiple times in notable venues such as Human Genetics, Mediators of Inflammation, and the Journal of Hepatology. These publications represent a consistent engagement with journals concentrating on genetics, inflammation, and hepatology.

Best Publications

  • Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33

    Sandrine Marquet;Laurent Abel;Dominique Hillaire;Hélia Dessein

  • Evidence for an association between human resistance to Schistosoma mansoni and high anti-larval IgE levels.

    Pascal Rihet;Christian E. Demeure;Alain Bourgois;Aluizio Prata

  • IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani

    Maira G.R. Pitta;Audrey Romano;Sandrine Cabantous;Sandrine Henri

  • The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase.

    Goudot-Crozel;D Caillol;M Djabali;A J Dessein

  • Severe Hepatic Fibrosis in Schistosoma mansoni Infection Is Controlled by a Major Locus That Is Closely Linked to the Interferon-γ Receptor Gene

    Alain J. Dessein;Dominique Hillaire;Nasr Eldin M.A. Elwali;Sandrine Marquet

  • Cytokine Regulation of Periportal Fibrosis in Humans Infected with Schistosoma mansoni: IFN-γ Is Associated with Protection Against Fibrosis and TNF-α with Aggravation of Disease

    Sandrine Henri;Christophe Chevillard;Adil Mergani;Patricia Paris

  • Resistance to Schistosoma mansoni in Humans: Influence of the IgE/IgG4 Balance and IgG2 in Immunity to Reinfection after Chemotherapy

    C. E. Demeure;P. Rihet;L. Abel;M. Ouattara

  • Evidence for the segregation of a major gene in human susceptibility/resistance to infection by Schistosoma mansoni.

    L Abel;F Demenais;A Prata;A E Souza

  • Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis

    Adnene Salhi;Virmondes Rodrigues;Ferrucio Santoro;Helia Dessein

  • Human resistance to Schistosoma mansoni is associated with IgG reactivity to a 37-kDa larval surface antigen.

    A J Dessein;M Begley;C Demeure;D Caillol

  • Symptomatic human neurocysticercosis--age, sex and exposure factors relating with disease heterogeneity.

    Agnès Fleury;Alain Dessein;Pierre Marie Preux;Michel Dumas

  • Susceptibility to Periportal (Symmers) Fibrosis in Human Schistosoma mansoni Infections: Evidence That Intensity and Duration of Infection, Gender, and Inherited Factors Are Critical in Disease Progression

    Qurashi Mohamed-Ali;Nasr-Eldin M. A. Elwali;Ahmed A. Abdelhameed;Adil Mergani

  • Immune evasion by Schistosoma mansoni: loss of susceptibility to antibody or complement-dependent eosinophil attack by schistosomula cultured in medium free of macromolecules.

    A. Dessein;J. C. Samuelson;A. E. Butterworth;Maureen Hogan

  • Visceral leishmaniasis in eastern Sudan: parasite identification in humans and dogs; host-parasite relationships.

    Jacques Dereure;Sayda Hassan El-Safi;Bruno Bucheton;Mickaël Boni

  • Th1/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-γ production

    Lúcio Roberto Castellano;Dalmo Correia Filho;Laurent Argiro;Helia Dessein

  • The impact of host genetics on susceptibility to human infectious diseases

    Laurent Abel;Alain J Dessein

  • Vanin-1–/– mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores

    Florent Martin;Marie-France Penet;Fabrice Malergue;Hubert Lepidi

  • The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in eastern Sudan.

    Bruno Bucheton;Musa Mohamed Kheir;Sayda Hassan El-Safi;Awad Hammad

  • Linkage analysis of blood Plasmodium falciparum levels: interest of the 5q31-q33 chromosome region.

    Andre Garcia;Sandrine Marquet;Bruno Bucheton;Dominique Hillaire

  • Interactions between human eosinophils and schistosomula of schistosoma mansoni. II. The mechanism of irreversible eosinophil adherence

    AE Butterworth;MA Vadas;DL Wassom;A Dessein

  • IFN-gamma polymorphisms (IFN-gamma +2109 and IFN-gamma +3810) are associated with severe hepatic fibrosis in human hepatic schistosomiasis (Schistosoma mansoni).

    Christophe Chevillard;Carole Eboumbou Moukoko;Nasr Eldin M.A. Elwali;Jay H. Bream

  • Strong serum inhibition of specific IgE correlated to competing IgG4, revealed by a new methodology in subjects from a S. mansoni endemic area.

    Pascal Rihet;Christian E. Demeure;Alain J. Dessein;Alain Bourgois

Frequent Co-Authors

Laurent Abel
Laurent Abel Université Paris Cité
Ogobara K. Doumbo
Ogobara K. Doumbo University of Bamako
Sandrine Henri
Sandrine Henri Centre d’Immunologie de Marseille-Luminy
Edda Sciutto
Edda Sciutto National Autonomous University of Mexico
Gladis Fragoso
Gladis Fragoso National Autonomous University of Mexico
Sima Rafati
Sima Rafati Pasteur Institute of Iran
Yannick Allanore
Yannick Allanore Université Paris Cité
Pierre Bongrand
Pierre Bongrand Aix-Marseille University
Philippe Halfon
Philippe Halfon Université Paris Cité
Jay H. Bream
Jay H. Bream Johns Hopkins University

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