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D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
37263
World Ranking
9429
National Ranking
4155

Overview

Julio A. Aguirre-Ghiso is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans multiple disciplines, primarily within Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's work is concentrated in key subfields including Molecular Biology, Oncology, Cancer Research, Immunology, and Cell Biology. Their research addresses several significant topics such as Cancer Cells and Metastasis, Epigenetics and DNA Methylation, Ubiquitin and proteasome pathways, Cancer Research and Treatments, Cancer Immunotherapy and Biomarkers, Immune cells in cancer, and Histone Deacetylase Inhibitors Research.

Julio A. Aguirre-Ghiso has contributed to numerous scientific publications, with a frequent presence in the following venues:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Cancer
  • Cancer Cell

Some of their recent published papers include:

  • Immunology of COVID-19: Current State of the Science, 2020, Immunity
  • Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells, 2021, Nature
  • A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy, 2021, Nature Cancer
  • The current paradigm and challenges ahead for the dormancy of disseminated tumor cells, 2020, Nature Cancer
  • Stromal changes in the aged lung induce an emergence from melanoma dormancy, 2022, Nature

The scientist has frequently collaborated with several researchers, including Ana Rita Nobre, Deepak Kumar Singh, Erica Dalla, Eduardo Farias, and Ashani T. Weeraratna.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Models, mechanisms and clinical evidence for cancer dormancy.

    Julio A. Aguirre-Ghiso

  • Immunology of COVID-19: Current State of the Science.

    Nicolas Vabret;Graham J. Britton;Conor Gruber;Samarth Hegde

  • Mechanisms of disseminated cancer cell dormancy: an awakening field

    María Soledad Sosa;Paloma Bragado;Julio A. Aguirre-Ghiso

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Early dissemination seeds metastasis in breast cancer

    Hedayatollah Hosseini;Milan M. S. Obradović;Martin Hoffmann;Kathryn L. Harper

  • Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.

    María Casanova-Acebes;Erica Dalla;Andrew M. Leader;Jessica LeBerichel

  • ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).

    Julio A. Aguirre-Ghiso;Yeriel Estrada;David Liu;Liliana Ossowski

  • Mechanism of early dissemination and metastasis in Her2 + mammary cancer

    Kathryn L. Harper;Maria Soledad Sosa;David Entenberg;Hedayatollah Hosseini

  • Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.

    Julio A. Aguirre-Ghiso;David Liu;Andrea Mignatti;Katherine Kovalski

  • Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

    Liliana Ossowski;Julio A Aguirre-Ghiso

  • TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

    Paloma Bragado;Yeriel Estrada;Falguni Parikh;Sarah Krause

  • Functional Coupling of p38-Induced Up-regulation of BiP and Activation of RNA-Dependent Protein Kinase–Like Endoplasmic Reticulum Kinase to Drug Resistance of Dormant Carcinoma Cells

    Aparna C. Ranganathan;Lin Zhang;Alejandro P. Adam;Julio A. Aguirre-Ghiso

  • Macrophages orchestrate breast cancer early dissemination and metastasis

    Nina Linde;Nina Linde;Maria Casanova-Acebes;Maria Soledad Sosa;Arthur Mortha;Arthur Mortha

  • ATF6α-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo

    Denis M. Schewe;Julio A. Aguirre-Ghiso

  • PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment.

    Alvaro Avivar-Valderas;Eduardo Salas;Ekaterina Bobrovnikova-Marjon;J. Alan Diehl

  • Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments.

    Georg Fluegen;Georg Fluegen;Alvaro Avivar-Valderas;Yarong Wang;Michael R. Padgen

  • Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.

    Kip M. Connor;Sita Subbaram;Kevin J. Regan;Kristin K. Nelson

  • ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK)1

    J.A. Aguirre-Ghiso;Y. Estrada;D. Liu;L. Ossowski

Frequent Co-Authors

John S. Condeelis
John S. Condeelis Albert Einstein College of Medicine
Patricia J. Keely
Patricia J. Keely University of Wisconsin–Madison
Christoph Klein
Christoph Klein Ludwig-Maximilians-Universität München
Andrew E. Aplin
Andrew E. Aplin Thomas Jefferson University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Roger J. Davis
Roger J. Davis University of Massachusetts Chan Medical School
Sergio Lavandero
Sergio Lavandero University of Chile
Jayanta Debnath
Jayanta Debnath University of California, San Francisco
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai

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