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Andrew E. Aplin

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
14676
World Ranking
10189
National Ranking
4450

Andrew E. Aplin publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Andrew E. Aplin sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 235 publications — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Andrew E. Aplin D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Andrew E. Aplin sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Andrew E. Aplin is affiliated with Thomas Jefferson University in the United States. Their research spans multiple fields with a focus on biochemistry, genetics, and molecular biology, as well as medicine. Within these broad areas, their work is concentrated on several subfields including molecular biology, ophthalmology, oncology, immunology, and cell biology.

Their main research topics cover diverse aspects of cancer biology and treatment strategies, particularly in ocular oncology and treatments, melanoma and MAPK pathways, immunotherapy and immune responses, ubiquitin and proteasome pathways, protein degradation and inhibitors, CAR-T cell therapy research, and cancer-related molecular pathways.

Aplin has contributed to notable recent publications including:

  • Melanoma models for the next generation of therapies, 2021, Cancer Cell
  • Fueling the Fire: Inflammatory Forms of Cell Death and Implications for Cancer Immunotherapy, 2021, Cancer Discovery
  • Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway, 2022, Journal of Experimental & Clinical Cancer Research
  • Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma, 2022, Nature Communications
  • Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma, 2021, Clinical Cancer Research

They frequently collaborate with several researchers including:

  • Timothy J. Purwin
  • Vivian Chua
  • Claudia Capparelli
  • Takami Sato
  • Manoela Tiago

Aplin has published extensively in well-known scientific venues, with a particular concentration of work appearing in:

  • Cancer Research
  • UNC Libraries
  • Molecular Cancer Research
  • Clinical Cancer Research
  • Molecular Cancer Therapeutics

Best Publications

  • Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins

    A. E. Aplin;A. Howe;S. K. Alahari;R. L. Juliano

  • Integrin signaling and cell growth control.

    Alan Howe;Andrew E. Aplin;Suresh K. Alahari;Rudolph L Juliano

  • Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.

    Corey Rogers;Dan A. Erkes;Alexandria Nardone;Andrew E. Aplin

  • m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

    Seungwon Yang;Jiangbo Wei;Yan-Hong Cui;Gayoung Park

  • Cell adhesion molecules, signal transduction and cell growth.

    Andrew E. Aplin;Alan K. Howe;Rl L. Juliano

  • Anchorage-dependent ERK signaling: mechanisms and consequences

    Alan K. Howe;Andrew E. Aplin;Rudolph L Juliano

  • Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis

    Dan A. Erkes;Weijia Cai;Ileine M. Sanchez;Timothy J. Purwin

  • Integrin-mediated Activation of MAP Kinase Is Independent of FAK: Evidence for Dual Integrin Signaling Pathways in Fibroblasts

    Tsung H. Lin;Andrew E. Aplin;Yu Shen;Qiming Chen

  • Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1.

    Andrew E. Aplin;Sheryl A. Stewart;Richard K. Assoian;R.L. Juliano

  • Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.

    Kip M. Connor;Sita Subbaram;Kevin J. Regan;Kristin K. Nelson

  • Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3

    Ethan V. Abel;Kevin J. Basile;Curtis H. Kugel;Agnieszka K. Witkiewicz

  • In Vitro Phosphorylation of the Cytoplasmic Domain of the Amyloid Precursor Protein by Glycogen Synthase Kinase‐3β

    Aplin Ae;Gibb Gm;Jacobsen Js;Gallo Jm

  • Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles.

    A. Aplin;T. Jasionowski;D. L. Tuttle;S. E. Lenk

  • Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway

    Andrew E. Aplin;R. L. Juliano

  • Akt3-Mediated Resistance to Apoptosis in B-RAF-Targeted Melanoma Cells

    Yongping Shao;Andrew E. Aplin

  • Melanoma models for the next generation of therapies

    E. Elizabeth Patton;Kristen L. Mueller;David J. Adams;Niroshana Anandasabapathy

  • Integrin regulation of cell signalling and motility.

    R.L. Juliano;P. Reddig;S. Alahari;M. Edin

  • Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling

    Kavita V Bhatt;Laurie S Spofford;Gazelle Aram;Meghan McMullen

  • TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells

    Michele B. Weiss;Ethan V. Abel;Melanie M. Mayberry;Kevin J. Basile

  • Mcl-1 is required for melanoma cell resistance to anoikis.

    Karen Boisvert-Adamo;Whitney Longmate;Ethan V. Abel;Andrew E. Aplin

Frequent Co-Authors

Michael A. Davies
Michael A. Davies The University of Texas MD Anderson Cancer Center
Reinhard Dummer
Reinhard Dummer University of Zurich
Rudy L. Juliano
Rudy L. Juliano University of North Carolina at Chapel Hill
Julio A. Aguirre-Ghiso
Julio A. Aguirre-Ghiso Icahn School of Medicine at Mount Sinai
Marcus Bosenberg
Marcus Bosenberg Yale University
Xiaowei Xu
Xiaowei Xu University of Pennsylvania
Heinz Arnheiter
Heinz Arnheiter National Institutes of Health
Robert N. Kelsh
Robert N. Kelsh University of Bath
Yu-Ying He
Yu-Ying He Duke University
Paolo Fortina
Paolo Fortina Thomas Jefferson University

External Links

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