D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 43 Citations 7,366 119 World Ranking 14440 National Ranking 422

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Apoptosis

Nikolas K. Haass mainly investigates Melanoma, Cancer research, Cell biology, Cell culture and Protein kinase A. The concepts of his Melanoma study are interwoven with issues in Cadherin, Signal transduction, Cell adhesion, Cell cycle and Kinase. His study looks at the relationship between Cell cycle and fields such as Drug response, as well as how they intersect with chemical problems.

Nikolas K. Haass interconnects Cell growth, Apoptosis, Molecular biology, Cytotoxic T cell and Drug resistance in the investigation of issues within Cancer research. His study in Cell biology is interdisciplinary in nature, drawing from both Cancer cell, Cytoskeleton and Melanocyte. His Cell culture research is multidisciplinary, incorporating perspectives in Tropomyosin, Actin, Gene isoform and Actin cytoskeleton.

His most cited work include:

  • Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity (1071 citations)
  • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases (392 citations)
  • Adhesion, migration and communication in melanocytes and melanoma (290 citations)

What are the main themes of his work throughout his whole career to date?

Melanoma, Cancer research, Cell biology, Cell cycle and Chemistry are his primary areas of study. His Melanoma research includes themes of Tumor microenvironment, Cancer cell, Apoptosis, Immunology and Microphthalmia-associated transcription factor. His Cancer research research is multidisciplinary, incorporating elements of Cancer, Metastasis, Cell culture, Drug resistance and In vivo.

His work carried out in the field of Cell biology brings together such families of science as Downregulation and upregulation and Melanocyte. His work on Cell cycle checkpoint as part of general Cell cycle research is frequently linked to Mathematical model, thereby connecting diverse disciplines of science. His studies deal with areas such as Flow cytometry and Cell growth as well as Cell.

He most often published in these fields:

  • Melanoma (98.44%)
  • Cancer research (63.04%)
  • Cell biology (41.25%)

What were the highlights of his more recent work (between 2018-2021)?

  • Melanoma (98.44%)
  • Cancer research (63.04%)
  • Cell cycle (34.24%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Melanoma, Cancer research, Cell cycle, Biological system and Cell. His Melanoma research is multidisciplinary, relying on both Cancer cell, Phenotype, Microphthalmia-associated transcription factor and Cell biology. His Cancer research study combines topics in areas such as Cancer, Metastasis, Immune system and In vivo.

His work in the fields of Cell cycle, such as Cell cycle checkpoint, overlaps with other areas such as Mathematical model and Replicate. His research in Biological system intersects with topics in Cancer treatment and Melanoma cell line. JARID1B and Demethylase is closely connected to Cell growth in his research, which is encompassed under the umbrella topic of Cell.

Between 2018 and 2021, his most popular works were:

  • BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. (54 citations)
  • RAB27A promotes melanoma cell invasion and metastasis via regulation of pro‐invasive exosomes (33 citations)
  • RAB27A promotes melanoma cell invasion and metastasis via regulation of pro‐invasive exosomes (33 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Apoptosis

His main research concerns Melanoma, Cancer research, Cancer, Biological system and Cell cycle. His Melanoma study integrates concerns from other disciplines, such as Phenotype, Cancer cell and Cell biology. His research in Cell biology focuses on subjects like Cell Plasticity, which are connected to Cell.

Nikolas K. Haass usually deals with Cancer research and limits it to topics linked to Apoptosis and Gemcitabine. His study on Metastasis is often connected to Bortezomib as part of broader study in Cancer. His biological study spans a wide range of topics, including Spheroid and Tumour spheroid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai;John T. Lee;Weiru Wang;Jiazhong Zhang.
Proceedings of the National Academy of Sciences of the United States of America (2008)

1354 Citations

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

Keiran S.M. Smalley;Nikolas K. Haass;Patricia A. Brafford;Mercedes Lioni.
Molecular Cancer Therapeutics (2006)

481 Citations

Adhesion, migration and communication in melanocytes and melanoma

Nikolas K. Haass;Keiran S. M. Smalley;Ling Li;Meenhard Herlyn.
Pigment Cell Research (2005)

426 Citations

An Organometallic Protein Kinase Inhibitor Pharmacologically Activates p53 and Induces Apoptosis in Human Melanoma Cells

Keiran S.M. Smalley;Rooha Contractor;Nikolas K. Haass;Angela N. Kulp.
Cancer Research (2007)

252 Citations

Normal human melanocyte homeostasis as a paradigm for understanding melanoma.

Nikolas K. Haass;Meenhard Herlyn.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research (2005)

239 Citations

The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression When Combined with Docetaxel

Nikolas K Haass;Katrin Sproesser;Thiennga K Nguyen;Rooha Contractor.
Clinical Cancer Research (2008)

218 Citations

The Role of Altered Cell–Cell Communication in Melanoma Progression

Nikolas K Haass;Keiran S M Smalley;Meenhard Herlyn.
Journal of Molecular Histology (2003)

207 Citations

Targeting glutamine transport to suppress melanoma cell growth.

Qian Wang;Qian Wang;Kimberley A. Beaumont;Kimberley A. Beaumont;Nicholas J. Otte;Nicholas J. Otte;Josep Font;Josep Font.
International Journal of Cancer (2014)

190 Citations

PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas.

John T. Lee;Ling Li;Patricia A. Brafford;Marcia van den Eijnden.
Pigment Cell & Melanoma Research (2010)

173 Citations

Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion.

Keiran S.M. Smalley;Patricia Brafford;Nikolas K. Haass;Johanna M. Brandner.
American Journal of Pathology (2005)

165 Citations

Editorial Boards

Experimental Dermatology
(Impact Factor: 4.511)

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