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D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
8854
World Ranking
19083
National Ranking
564

Overview

Nikolas K. Haass is affiliated with the University of Queensland in Australia. Their research spans multiple disciplines within the life sciences, focusing primarily on biochemistry, genetics, molecular biology, and medicine. They have contributed extensively to molecular biology and oncology, as well as modeling and simulation, cell biology, and immunology.

The scientist's research topics include:

  • Cancer Cells and Metastasis
  • Mathematical Biology Tumor Growth
  • Gene Regulatory Network Analysis
  • Cell Image Analysis Techniques
  • Cellular Mechanics and Interactions
  • Immunotherapy and Immune Responses
  • Melanoma and MAPK Pathways

Nikolas K. Haass has authored several papers, with recent publications such as:

  • "Mathematical Model of Tumour Spheroid Experiments with Real-Time Cell Cycle Imaging" (2021), Bulletin of Mathematical Biology
  • "Examining Go-or-Grow Using Fluorescent Cell-Cycle Indicators and Cell-Cycle-Inhibiting Drugs" (2020), Biophysical Journal
  • "Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity" (2021), Proceedings of the National Academy of Sciences
  • "Designing and interpreting 4D tumour spheroid experiments" (2022), Communications Biology
  • "A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling" (2022), Journal of The Royal Society Interface

Frequent co-authors include:

  • Gency Gunasingh
  • Matthew J. Simpson
  • Ryan J. Murphy
  • Alexander P. Browning
  • Loredana Spoerri

The scientist's work has been published in a variety of venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • Bulletin of Mathematical Biology
  • Biophysical Journal
  • British Journal of Dermatology

Best Publications

  • Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

    James Tsai;John T. Lee;Weiru Wang;Jiazhong Zhang

  • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

    Keiran S.M. Smalley;Nikolas K. Haass;Patricia A. Brafford;Mercedes Lioni

  • Adhesion, migration and communication in melanocytes and melanoma

    Nikolas K. Haass;Keiran S. M. Smalley;Ling Li;Meenhard Herlyn

  • An Organometallic Protein Kinase Inhibitor Pharmacologically Activates p53 and Induces Apoptosis in Human Melanoma Cells

    Keiran S.M. Smalley;Rooha Contractor;Nikolas K. Haass;Angela N. Kulp

  • Normal human melanocyte homeostasis as a paradigm for understanding melanoma.

    Nikolas K. Haass;Meenhard Herlyn

  • The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression When Combined with Docetaxel

    Nikolas K Haass;Katrin Sproesser;Thiennga K Nguyen;Rooha Contractor

  • Targeting glutamine transport to suppress melanoma cell growth.

    Qian Wang;Qian Wang;Kimberley A. Beaumont;Kimberley A. Beaumont;Nicholas J. Otte;Nicholas J. Otte;Josep Font;Josep Font

  • The Role of Altered Cell–Cell Communication in Melanoma Progression

    Nikolas K Haass;Keiran S M Smalley;Meenhard Herlyn

  • A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

    Justine Stehn;Nikolas K Haass;Nikolas K Haass;Nikolas K Haass;Theresa Bonello;Melissa Desouza

  • Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion.

    Keiran S.M. Smalley;Patricia Brafford;Nikolas K. Haass;Johanna M. Brandner

  • PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas.

    John T. Lee;Ling Li;Patricia A. Brafford;Marcia van den Eijnden

  • A stress-induced early innate response causes multidrug tolerance in melanoma

    D Ravindran Menon;D Ravindran Menon;S Das;C Krepler;A Vultur

  • BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.

    Erinna F Lee;Tiffany J Harris;Sharon Tran;Marco Evangelista

  • Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.

    Farzana Ahmed;Nikolas K. Haass;Nikolas K. Haass

  • Real-time cell cycle imaging during melanoma growth, invasion, and drug response

    Nikolas K. Haass;Kimberley A. Beaumont;Kimberley A. Beaumont;David S. Hill;David S. Hill;Andrea Anfosso;Andrea Anfosso

  • In vitro three-dimensional tumor microenvironment models for anticancer drug discovery

    Keiran S M Smalley;Mercedes Lioni;Kazuhiro Noma;Nikolas K Haass

  • Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737

    Keryn M Lucas;Nethia Mohana-Kumaran;Diana Lau;Xu Dong Zhang

  • Modeling Melanoma In Vitro and In Vivo

    Kimberley A. Beaumont;Nethia Mohana-Kumaran;Nethia Mohana-Kumaran;Nikolas K. Haass;Nikolas K. Haass;Nikolas K. Haass

  • Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels

    Keiran S M Smalley;Rooha Contractor;Nikolas K Haass;John T Lee

  • Melanoma’s connections to the tumour microenvironment

    Johanna M. Brandner;Nikolas K. Haass;Nikolas K. Haass;Nikolas K. Haass

Frequent Co-Authors

Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
Brian Gabrielli
Brian Gabrielli University of Queensland
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Matthew J. Simpson
Matthew J. Simpson Queensland University of Technology
Riccardo Dolcetti
Riccardo Dolcetti Peter MacCallum Cancer Centre
Graham J. Mann
Graham J. Mann Australian National University
Keith T. Flaherty
Keith T. Flaherty Harvard University
Peter Hersey
Peter Hersey University of Sydney
John Allen
John Allen Coventry University
Osami Kanagawa
Osami Kanagawa École Normale Supérieure de Lyon

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