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Genetics

D-Index
59
Citations
9890
World Ranking
3267
National Ranking
160

Overview

Wen-Hui Shen is a researcher affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their scientific contributions span multiple disciplines, including biochemistry, genetics, molecular biology, agricultural and biological sciences, and medicine. Their work has notable relevance in plant science, molecular biology, immunology, oncology, and electrical and electronic engineering.

The research focus includes several main topics: plant molecular biology research, light effects on plants, cancer immunotherapy and biomarkers, immunotherapy and immune responses, immune cells in cancer, genomics and chromatin dynamics, and plant gene expression analysis.

Among their recent papers are the following:

  • Structural insights into partner selection for MYB and bHLH transcription factor complexes (2022, Nature Plants)
  • Histone modification and chromatin remodeling in plant response to pathogens (2022, Frontiers in Plant Science)
  • Arabidopsis SDG8 Potentiates the Sustainable Transcriptional Induction of the Pathogenesis-Related Genes PR1 and PR2 During Plant Defense Response (2020, Frontiers in Plant Science)
  • Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 (2022, Nature Communications)
  • Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy (2023, Journal for ImmunoTherapy of Cancer)

Frequent co-authors associated with Wen-Hui Shen include Aiwu Dong, Jiabing Wu, Kangxi Du, Jiachen Wang, and Liufan Yin. These collaborations underline a continued network of scientific engagement across multiple studies.

Key publication venues for Wen-Hui Shen encompass: Nature Communications, New Phytologist, Scientific Reports, Proceedings of the National Academy of Sciences, and The Plant Journal. These journals reflect a combination of research fields, including both plant biology and broader biological sciences.

Best Publications

  • Di- and Tri- but Not Monomethylation on Histone H3 Lysine 36 Marks Active Transcription of Genes Involved in Flowering Time Regulation and Other Processes in Arabidopsis thaliana

    Lin Xu;Zhong Zhao;Aiwu Dong;Ludivine Soubigou-Taconnat

  • Prevention of early flowering by expression of FLOWERING LOCUS C requires methylation of histone H3 K36

    Zhong Zhao;Yu Yu;Denise Meyer;Chengjun Wu

  • Polycomb Silencing of KNOX Genes Confines Shoot Stem Cell Niches in Arabidopsis

    Lin Xu;Wen-Hui Shen

  • Hairy roots are more sensitive to auxin than normal roots

    Wen Hui Shen;Annik Petit;Jean Guern;Jacques Tempé

  • Histone modifications in transcriptional activation during plant development.

    Alexandre Berr;Sarfraz Shafiq;Wen-Hui Shen

  • Arabidopsis AL PHD-PRC1 Complexes Promote Seed Germination through H3K4me3-to-H3K27me3 Chromatin State Switch in Repression of Seed Developmental Genes

    Anne Marie Molitor;Zhongyuan Bu;Yu Yu;Wen-Hui Shen

  • Arabidopsis Histone Methyltransferase SET DOMAIN GROUP8 Mediates Induction of the Jasmonate/Ethylene Pathway Genes in Plant Defense Response to Necrotrophic Fungi

    Alexandre Berr;Emily J. McCallum;Abdelmalek Alioua;Dimitri Heintz

  • The E2 ubiquitin‐conjugating enzymes, AtUBC1 and AtUBC2, play redundant roles and are involved in activation of FLC expression and repression of flowering in Arabidopsis thaliana

    Lin Xu;Rozenn Ménard;Alexandre Berr;Jörg Fuchs

  • Arabidopsis SET DOMAIN GROUP2 Is Required for H3K4 Trimethylation and Is Crucial for Both Sporophyte and Gametophyte Development

    Alexandre Berr;Emily J. Mccallum;Rozenn Menard;Denise Meyer

  • Null Mutation of AtCUL1 Causes Arrest in Early Embryogenesis in Arabidopsis

    Wen-Hui Shen;Yves Parmentier;Hanjo Hellmann;Esther Lechner

  • Arabidopsis NRP1 and NRP2 Encode Histone Chaperones and Are Required for Maintaining Postembryonic Root Growth

    Yan Zhu;Yan Zhu;Aiwu Dong;Denise Meyer;Olivier Pichon

  • The Arabidopsis PRC1-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth

    Donghong Chen;Anne Molitor;Chunlin Liu;Wen-Hui Shen

  • The Tobacco A-Type Cyclin, Nicta;CYCA3;2, at the Nexus of Cell Division and Differentiation

    Yu Yu;Andre Steinmetz;Denise Meyer;A. Spencer Brown

  • Arabidopsis Flower and Embryo Developmental Genes are Repressed in Seedlings by Different Combinations of Polycomb Group Proteins in Association with Distinct Sets of Cis-regulatory Elements.

    Hua Wang;Chunmei Liu;Jingfei Cheng;Jian Liu

  • SET DOMAIN GROUP25 Encodes a Histone Methyltransferase and Is Involved in FLOWERING LOCUS C Activation and Repression of Flowering

    Alexandre Berr;Lin Xu;Juan Gao;Valérie Cognat

  • Multiple A-type cyclins express sequentially during the cell cycle in Nicotiana tabacum BY2 cells

    Jean-Philippe Reichheld;Nicole Chaubet;Wen Hui Shen;Jean-Pierre Renaudin

  • The plant E2F–Rb pathway and epigenetic control

    Wen-Hui Shen

  • H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice.

    Pengfei Sui;Jing Jin;Sheng Ye;Chen Mu

  • Cell cycle-dependent proteolysis and ectopic overexpression of cyclin B1 in tobacco BY2 cells.

    Marie Claire Criqui;Yves Parmentier;Aude Derevier;Wen-Hui Shen

  • Manipulation of leaf shape by modulation of cell division.

    Joanna Wyrzykowska;Stéphane Pien;Stéphane Pien;Wen Hui Shen;Wen Hui Shen;Andrew J Fleming;Andrew J Fleming

Frequent Co-Authors

Aiwu Dong
Aiwu Dong Fudan University
Barbara Hohn
Barbara Hohn Friedrich Miescher Institute
Pascal Genschik
Pascal Genschik University of Strasbourg
Jean Guern
Jean Guern Centre national de la recherche scientifique, CNRS
Hélène Barbier-Brygoo
Hélène Barbier-Brygoo Centre national de la recherche scientifique, CNRS
Gloria M. Coruzzi
Gloria M. Coruzzi New York University
Jean-Pierre Renou
Jean-Pierre Renou University of Angers
Andrew J. Fleming
Andrew J. Fleming University of Sheffield
Jörg Fuchs
Jörg Fuchs Leibniz Association
Pierre Goloubinoff
Pierre Goloubinoff University of Lausanne

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