John M. Koomen

Overview

Best Publications

• HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin

  Xiaohong Zhang;Zhigang Yuan;Yingtao Zhang;Sarah Yong

  795
  Citations

• PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

  Kim H.T. Paraiso;Yun Xiang;Vito W. Rebecca;Ethan V. Abel

  618
  Citations

• Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

  Steven A. Carr;Susan E. Abbatiello;Bradley L. Ackermann;Christoph Borchers

  593
  Citations

• Feature extraction and quantification for mass spectrometry in biomedical applications using the mean spectrum

  Jeffrey S. Morris;Kevin R. Coombes;John Koomen;Keith A. Baggerly

  416
  Citations

• Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial.

  Benjamin C. Creelan;Chao Wang;Jamie K. Teer;Eric M. Toloza

  401
  Citations

• Anion template effect on the self-assembly and interconversion of metallacyclophanes.

  Cristian Saul Campos-Fernández;Brandi L. Schottel;Helen T. Chifotides;Jitendra K. Bera

  362
  Citations

• Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

  Arif Yurdagul;Manikandan Subramanian;Xiaobo Wang;Scott B. Crown

  336
  Citations

• Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities

  Guangan He;Zahid H Siddik;Zaifeng Huang;Ruoning Wang

  326
  Citations

• A chemical and phosphoproteomic characterization of dasatinib action in lung cancer.

  Jiannong Li;Uwe Rix;Bin Fang;Yun Bai

  313
  Citations

• Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery.

  John M. Koomen;Donghui Li;Lian Chun Xiao;Thomas C. Liu

  258
  Citations

• Comparative Analyses of the Three-dimensional Structures and Enzymatic Properties of α, β, γ, and δ Isoforms of Ca2+-Calmodulin-dependent Protein Kinase II

  Tara R. Gaertner;Steven J. Kolodziej;Dan Wang;Ryuji Kobayashi

  225
  Citations

• SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities.

  Lirong Peng;Zhigang Yuan;Hongbo Ling;Kenji Fukasawa

  223
  Citations

• Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins.

  John M. Koomen;Lichen Nancy Shih;Kevin R. Coombes;Donghui Li

  203
  Citations

• Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation

  Kiran Mahajan;Domenico Coppola;Sridevi Challa;Bin Fang

  202
  Citations

• The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms

  Kim H.T. Paraiso;H. Eirik Haarberg;Elizabeth Wood;Vito W. Rebecca

  192
  Citations

• Fine-tuning the ring-size of metallacyclophanes: a rational approach to molecular pentagons.

  Cristian Saul Campos-Fernández;Rodolphe Clérac;John M. Koomen;David H. Russell

  183
  Citations

• Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane.

  Mehdi Damaghi;Narges K. Tafreshi;Mark C. Lloyd;Robert Sprung

  172
  Citations

• Lipid/Peptide/Nucleotide Separation with MALDI-Ion Mobility-TOF MS

  Amina S. Woods;Michael Ugarov;Tom Egan;John Koomen

  172
  Citations

• MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.

  Yanqi Chang;Lidong Sun;Kenji Kokura;John R. Horton

  167
  Citations

• Abstract 5370: PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

  Kim H. Paraiso;Vito Rebecca;Inna V. Fedorenko;Yun Xiang

  2
  Citations