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Gerard C. Blobe

Gerard C. Blobe

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18380
World Ranking
10595
National Ranking
4603

Overview

Gerard C. Blobe is affiliated with Duke University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans multiple subfields including molecular biology, oncology, cancer research, cell biology, and biomedical engineering.

The main topics of their work include:

  • TGF-β signaling in diseases
  • Cell Adhesion Molecules Research
  • Angiogenesis and VEGF in Cancer
  • Axon Guidance and Neuronal Signaling
  • Cancer, Hypoxia, and Metabolism
  • Gastric Cancer Management and Outcomes
  • Caveolin-1 and cellular processes

Their recent papers demonstrate a focus on cellular signaling and cancer biology. Selected publications include:

  • The role of the extracellular matrix protein TGFBI in cancer, 2021, Cellular Signalling
  • TGF-β superfamily co-receptors in cancer, 2021, Developmental Dynamics
  • NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting, 2024, Communications Biology
  • Cabozantinib and Panitumumab for RAS Wild-Type Metastatic Colorectal Cancer, 2021, The Oncologist
  • ALK1 regulates the internalization of endoglin and the type III TGF-β receptor, 2021, Molecular Biology of the Cell

Gerard C. Blobe frequently collaborates with other researchers in their field. Notable co-authors include John B. Pawlak, Swati Sharma, Marcelo Ehrlich, Yoav I. Henis, and Richard Superfine. Each of these collaborators has worked with Blobe on multiple occasions, indicating ongoing partnerships in research efforts.

Their work has been published repeatedly in venues such as Cancer Research, UNC Libraries, Cellular Signalling, Developmental Dynamics, and Communications Biology. Cancer Research and UNC Libraries, in particular, have featured several of their publications, reflecting a consistent engagement with cancer biology and related disciplines.

Best Publications

  • Role of transforming growth factor beta in human disease.

    Gerard C. Blobe;William P. Schiemann;Harvey F. Lodish

  • Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

    Suraj Peri;Suraj Peri;J. Daniel Navarro;J. Daniel Navarro;Ramars Amanchy;Troels Z. Kristiansen;Troels Z. Kristiansen

  • Role of Transforming Growth Factor Beta in Human Cancer

    Rebecca L. Elliott;Gerard C. Blobe

  • Role of transforming growth factor-β superfamily signaling pathways in human disease

    Kelly J. Gordon;Gerard C. Blobe

  • Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

    Vinay Swaminathan;Karthikeyan Mythreye;E. Tim O'Brien;Andrew Berchuck

  • Regulation of protein kinase C and role in cancer biology.

    Gerard C. Blobe;Lina M. Obeid;Yusuf A. Hannun

  • ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling

    Wei Chen;Kellye C. Kirkbride;Tam How;Christopher D. Nelson

  • The type III TGF-β receptor suppresses breast cancer progression

    Mei Dong;Tam How;Kellye C. Kirkbride;Kelly J. Gordon

  • Role of transforming growth factor-β in hematologic malignancies

    Mei Dong;Gerard C. Blobe

  • Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C

    Wasiuddin A. Khan;Gerard C. Blobe;Yusuf A. Hannun

  • A Novel Mechanism for Regulating Transforming Growth Factor β (TGF-β) Signaling FUNCTIONAL MODULATION OF TYPE III TGF-β RECEPTOR EXPRESSION THROUGH INTERACTION WITH THE PDZ DOMAIN PROTEIN, GIPC

    Gerard C. Blobe;Xuedong Liu;Shijing J. Fang;Tam How

  • Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

    Dereje D. Jima;Jenny Zhang;Cassandra Jacobs;Kristy L. Richards

  • Bone morphogenetic proteins signal through the transforming growth factor-β type III receptor

    Kellye C. Kirkbride;Todd A. Townsend;Monique W. Bruinsma;Joey V. Barnett

  • Roles for the type III TGF-β receptor in human cancer

    Catherine E. Gatza;Sun Young Oh;Gerard C. Blobe

  • Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha.

    G C Blobe;C W Sachs;W A Khan;D Fabbro

  • Context-specific Effects of Fibulin-5 (DANCE/EVEC) on Cell Proliferation, Motility, and Invasion FIBULIN-5 IS INDUCED BY TRANSFORMING GROWTH FACTOR-β AND AFFECTS PROTEIN KINASE CASCADES

    William P. Schiemann;William P. Schiemann;Gerard C. Blobe;Gerard C. Blobe;Dario E. Kalume;Akhilesh Pandey

  • Phosphorylation Specificities of Protein Kinase C Isozymes for Bovine Cardiac Troponin I and Troponin T and Sites within These Proteins and Regulation of Myofilament Properties

    Nathan M. Jideama;Thomas A. Noland;Robert L. Raynor;Gerard C. Blobe

  • Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling

    Gerard C. Blobe;Gerard C. Blobe;William P Schiemann;Marie Claude Pepin;Michel Beauchemin

  • The Type III Transforming Growth Factor-β Receptor as a Novel Tumor Suppressor Gene in Prostate Cancer

    Ryan S. Turley;Elizabeth C. Finger;Nadine Hempel;Tam How

  • Heparan sulfate signaling in cancer.

    Erik H. Knelson;Jasmine C. Nee;Gerard C. Blobe

Frequent Co-Authors

Michael A. Morse
Michael A. Morse Duke University
Herbert Hurwitz
Herbert Hurwitz Duke University
Johanna C. Bendell
Johanna C. Bendell Sarah Cannon Research Institute
Yusuf A. Hannun
Yusuf A. Hannun Stony Brook University
Donna Niedzwiecki
Donna Niedzwiecki Duke University
Lina M. Obeid
Lina M. Obeid Stony Brook University
Christopher G. Willett
Christopher G. Willett Duke University
Jason D. Lee
Jason D. Lee Princeton University
William P. Schiemann
William P. Schiemann Case Western Reserve University
Nicholas Katsanis
Nicholas Katsanis Galatea Bio Inc

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