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Edward B. Leof

Edward B. Leof

Mayo Clinic
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11850
World Ranking
13827
National Ranking
5850

Edward B. Leof publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Edward B. Leof sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 123 publications — 13th percentile

13% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Edward B. Leof D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Edward B. Leof sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Edward B. Leof is affiliated with the Mayo Clinic in the United States. Their research primarily focuses on medicine, with significant contributions in the fields of biochemistry, genetics, and molecular biology. Their subfields include pulmonary and respiratory medicine, molecular biology, epidemiology, immunology, and cell biology.

Leof's scientific work covers several key topics: interstitial lung diseases and idiopathic pulmonary fibrosis, developmental biology and gene regulation, TGF-β signaling in diseases, medical imaging and pathology studies, pleural and pulmonary diseases, neonatal respiratory health research, and autophagy in disease and therapy.

The frequent venues where Leof publishes include:

  • The FASEB Journal
  • Cells
  • PLoS Biology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent papers authored or coauthored by Leof are:

  • IPF pathogenesis is dependent upon TGFβ induction of IGF-1, 2020, The FASEB Journal
  • SIRT7-mediated modulation of glutaminase 1 regulates TGF-β-induced pulmonary fibrosis, 2020, The FASEB Journal
  • Vardenafil Activity in Lung Fibrosis and In Vitro Synergy with Nintedanib, 2021, Cells
  • A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila, 2022, PLoS Biology
  • Transforming growth factor beta induced PD-L1 expression promotes pro-fibrotic signaling, 2020, The Journal of Immunology

Frequent coauthors collaborating with Leof include Jeong Han Kang, Malay Choudhury, Andrew H. Limper, Aidan J. Peterson, and Stephen J. Murphy.

Best Publications

  • Growth Factors and Cancer

    Anton Scott Goustin;Edward B. Leof;Gary D. Shipley;Harold L. Moses

  • Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis

    Craig E. Daniels;Mark C. Wilkes;Maryanne Edens;Ted J. Kottom

  • Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor β: A proposed model for indirect mitogenesis involving autocrine activity

    Edward B. Leof;Jacqueline A. Proper;Anton Scott Goustin;Gary D. Shipley

  • Imatinib mesylate blocks a non-Smad TGF-β pathway and reduces renal fibrogenesis in vivo

    Shinong Wang;Mark C. Wilkes;Edward B. Leof;Raimund Hirschberg

  • Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells

    Robert J. Coffey;Edward B. Leof;Gary D. Shipley;Harold L. Moses

  • TGF‐β signaling: A tale of two responses

    Rod A. Rahimi;Edward B. Leof

  • Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells.

    Edward B. Leof;Walker Wharton;Judson J. Van Wyk;W.J. Pledger

  • Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest.

    Philip H. Howe;Giulio Draetta;Edward B. Leof

  • Ligand-dependent and -independent Transforming Growth Factor-β Receptor Recycling Regulated by Clathrin-mediated Endocytosis and Rab11

    Hugh Mitchell;Amit Choudhury;Richard E. Pagano;Edward B. Leof

  • Transforming Growth Factor-β Activation of Phosphatidylinositol 3-Kinase Is Independent of Smad2 and Smad3 and Regulates Fibroblast Responses via p21-Activated Kinase-2

    Mark C. Wilkes;Hugh Mitchell;Sumedha Gulati Penheiter;Jules J. Doré

  • Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway

    Sumedha G. Penheiter;Hugh Mitchell;Nandor Garamszegi;Maryanne Edens

  • Transforming growth factor β regulation of cell proliferation

    Harold L. Moses;Robert J. Coffey;Edward B. Leof;Russette M. Lyons

  • Transforming growth factors and control of neoplastic cell growth.

    Jorma Keski‐Oja;Edward B. Leof;Russette M. Lyons;Robert J. Coffey

  • Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells

    Sheng Cao;Usman Yaqoob;Amitava Das;Uday Shergill

  • Cell-Type-Specific Activation of PAK2 by Transforming Growth Factor β Independent of Smad2 and Smad3

    Mark C. Wilkes;Stephen J. Murphy;Nandor Garamszegi;Edward B. Leof

  • Noncanonical TGF-β pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

    Shinong Wang;Mark C. Wilkes;Edward B. Leof;Raimund Hirschberg

  • Transforming growth factor-β receptors interact with AP2 by direct binding to β2 subunit

    Diying Yao;Marcelo Ehrlich;Yoav I. Henis;Edward B. Leof

  • Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta

    J Keski-Oja;F Blasi;EB Leof;HL Moses

  • Platelet-Derived Growth Factor Signaling Through Ephrin-B2 Regulates Hepatic Vascular Structure and Function

    David Semela;David Semela;Amitava Das;Daniel Langer;Ningling Kang

  • Transforming growth factor type β regulation of actin mRNA

    Edward B. Leof;Jacqueline A. Proper;Michael J. Getz;Harold L. Moses

Frequent Co-Authors

Andrew H. Limper
Andrew H. Limper Mayo Clinic
Harold L. Moses
Harold L. Moses Vanderbilt University
Debabrata Mukhopadhyay
Debabrata Mukhopadhyay Mayo Clinic
Robert J. Coffey
Robert J. Coffey Vanderbilt University Medical Center
Santanu Bhattacharya
Santanu Bhattacharya Indian Institute of Science
John Varga
John Varga University of Michigan–Ann Arbor
Richard E. Pagano
Richard E. Pagano Mayo Clinic
Jorma Keski-Oja
Jorma Keski-Oja University of Helsinki
Alain Mauviel
Alain Mauviel Institute Curie
Ruth Lupu
Ruth Lupu Mayo Clinic

External Links

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Best Scientists Citing Edward B. Leof

Andrew H. Limper

Andrew H. Limper

Mayo Clinic

Publications: 47

Harold L. Moses

Harold L. Moses

Vanderbilt University

Publications: 43

Carl-Henrik Heldin

Carl-Henrik Heldin

Uppsala University

Publications: 26

John Varga

John Varga

University of Michigan–Ann Arbor

Publications: 26

Jorma Keski-Oja

Jorma Keski-Oja

University of Helsinki

Publications: 25

Rik Derynck

Rik Derynck

University of California, San Francisco

Publications: 24

Antonin de Fougerolles

Antonin de Fougerolles

Alnylam Pharmaceuticals (United States)

Publications: 22

David S. Salomon

David S. Salomon

National Institutes of Health

Publications: 21

Jeffrey L. Wrana

Jeffrey L. Wrana

Lunenfeld-Tanenbaum Research Institute

Publications: 21

Jörg H W Distler

Jörg H W Distler

University of Erlangen-Nuremberg

Publications: 19

Joan Massagué

Joan Massagué

Memorial Sloan Kettering Cancer Center

Publications: 19

Oliver Distler

Oliver Distler

University of Zurich

Publications: 18

Debabrata Mukhopadhyay

Debabrata Mukhopadhyay

Mayo Clinic

Publications: 18

Victor J. Thannickal

Victor J. Thannickal

Tulane University

Publications: 17

Aristidis Moustakas

Aristidis Moustakas

Uppsala University

Publications: 15

Fortunato Ciardiello

Fortunato Ciardiello

University of Campania "Luigi Vanvitelli"

Publications: 15

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