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85
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25319
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14655
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Research.com Recognitions

  • 2004 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Pathology and Forensic Medicine

Overview

Reinhard Büttner is affiliated with the University Hospital Cologne in Germany. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology, contributing a substantial body of work with 379 and 160 publications in these areas respectively.

Their subfields of study highlight a focus on Pulmonary and Respiratory Medicine, Oncology, Molecular Biology, Cancer Research, and Pathology and Forensic Medicine. These areas are reflected prominently in their academic output.

Specific research topics covered in their publications include Lung Cancer Treatments and Mutations, Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, Cancer Immunotherapy and Biomarkers, Radiomics and Machine Learning in Medical Imaging, Lung Cancer Research Studies, and Lung Cancer Diagnosis and Treatment.

Frequent co-authors collaborating with Büttner include Sabine Merkelbach-Bruse, Alexander Quaas, Hans Christian Reinhardt, Sebastian Michels, and Matthias Scheffler. This network reflects ongoing research partnerships within their disciplines.

The most common publication venues for Büttner's work incorporate Annals of Oncology, Nature Communications, Journal of Clinical Oncology, Lung Cancer, and Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin. These journals testify to the clinical and molecular focus of their investigations.

Among their recent papers are the following:

  • "Sarcoma classification by DNA methylation profiling," 2021, Nature Communications
  • "Precision medicine in non-small cell lung cancer: Current applications and future directions," 2020, Seminars in Cancer Biology
  • "The evolving landscape of biomarker testing for non-small cell lung cancer in Europe," 2021, Lung Cancer
  • "European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer," 2021, Annals of Oncology
  • "Quality control stress test for deep learning-based diagnostic model in digital pathology," 2021, Modern Pathology

In recognition of their work within Pathology and Forensic Medicine, Büttner received an award from the German National Academy of Sciences Leopoldina - Nationale Akademie der Wissenschaften in 2004.

Best Publications

  • Comprehensive genomic profiles of small cell lung cancer

    Julie George;Jing Shan Lim;Se Jin Jang;Yupeng Cun

  • LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription.

    Eric Metzger;Melanie Wissmann;Na Yin;Judith M. Müller

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

    Jonathan Weiss;Martin L. Sos;Danila Seidel;Martin Peifer

  • Defining high-fat-diet rat models: metabolic and molecular effects of different fat types

    R Buettner;K G Parhofer;M Woenckhaus;C E Wrede

  • Bats host major mammalian paramyxoviruses

    Jan Felix Drexler;Victor Max Corman;Marcel Alexander Müller;Gael Darren Maganga

  • Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

    Melanie Wissmann;Na Yin;Judith M. Müller;Holger Greschik

  • Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

    Soyoung Lim;Andreas Janzer;Astrid Becker;Andreas Zimmer

  • A genomics-based classification of human lung tumors

    Danila Seidel;Thomas Zander;Lukas C. Heukamp;Martin Peifer

  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Martin Peifer;Falk Hertwig;Frederik Roels;Daniel Dreidax

  • Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

    Mev Dominguez-Valentin;Julian R. Sampson;Toni T. Seppälä;Sanne W. ten Broeke

  • Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer

    Fengying Wu;Jue Fan;Yayi He;Anwen Xiong

  • Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

    Johannes H. Schulte;Soyoung Lim;Alexander Schramm;Nicolaus Friedrichs

  • Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence.

    Philip Kahl;Lucia Gullotti;Lukas Carl Heukamp;Susanne Wolf

  • FHL2, a Novel Tissue-Specific Coactivator of the Androgen Receptor

    Judith M. Müller;Ulrike Isele;Eric Metzger;Annette Rempel

  • Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate.

    Eva Wardelmann;Sabine Merkelbach-Bruse;Katharina Pauls;Nadja Thomas

  • Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control

    Kristina Hilger-Eversheim;Markus Moser;Hubert Schorle;Reinhard Buettner

  • Attenuation of allergic contact dermatitis through the endocannabinoid system

    Meliha Karsak;Evelyn Gaffal;Rahul Date;Lihua Wang-Eckhardt

  • Programmed Death-Ligand 1 Immunohistochemistry Testing: A Review of Analytical Assays and Clinical Implementation in Non-Small-Cell Lung Cancer.

    Reinhard Büttner;John R Gosney;Birgit Guldhammer Skov;Julien Adam

  • Corrigendum: Bats host major mammalian paramyxoviruses.

    Jan Felix Drexler;Victor Max Corman;Marcel Alexander Müller;Gael Darren Maganga

Frequent Co-Authors

Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Matthias Scheffler
Matthias Scheffler Fritz Haber Institute of the Max Planck Society
Roman K. Thomas
Roman K. Thomas University of Cologne
Manfred Dietel
Manfred Dietel Charité - University Medicine Berlin
Jürgen Wolf
Jürgen Wolf University of Cologne
Wilko Weichert
Wilko Weichert Technical University of Munich
Alain Chariot
Alain Chariot Fonds de la Recherche Scientifique – FNRS
Axel Heidenreich
Axel Heidenreich University of Cologne
Albrecht Stenzinger
Albrecht Stenzinger Heidelberg University
Roland Penzel
Roland Penzel University Hospital Heidelberg

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