Jason S. McLellan spends much of his time researching Virology, Antibody, Coronavirus, Epitope and Protein structure. His Virology research includes elements of Monoclonal antibody and Glycoprotein. His Monoclonal antibody research incorporates elements of Plasma protein binding, Somatic hypermutation and Memory B cell.
Jason S. McLellan has researched Antibody in several fields, including Molecular biology, Glycosylation, Antigen and Vaccination. His research ties Middle East respiratory syndrome coronavirus and Coronavirus together. His study in Epitope is interdisciplinary in nature, drawing from both Motavizumab and Biochemistry.
Jason S. McLellan mainly investigates Virology, Antibody, Virus, Glycoprotein and Epitope. His Virology study integrates concerns from other disciplines, such as Immune system, Monoclonal antibody and Antigen. The Antibody study combines topics in areas such as Protein structure, Glycan and Vaccination.
His work focuses on many connections between Protein structure and other disciplines, such as Viral protein, that overlap with his field of interest in Binding site and Cell biology. His Virus research is multidisciplinary, incorporating perspectives in Respiratory Syncytial Virus Vaccines, Fusion protein and Respiratory system. His Glycoprotein research focuses on subjects like Immunogenicity, which are linked to Ectodomain and Immunogen.
Jason S. McLellan focuses on Virology, Antibody, Epitope, Severe acute respiratory syndrome coronavirus 2 and Virus. His work on Neutralizing antibody as part of his general Virology study is frequently connected to Coronavirus, thereby bridging the divide between different branches of science. His work deals with themes such as In vitro, Viral replication, Antigen and Cell biology, which intersect with Antibody.
His Epitope research is multidisciplinary, incorporating elements of Immunoglobulin G and Lipid bilayer fusion. Jason S. McLellan interconnects Memory B cell, Genome, Respiratory system and Virulence in the investigation of issues within Virus. In the subject of general Glycoprotein, his work in Glycan is often linked to Trimer, thereby combining diverse domains of study.
His main research concerns Virology, Antibody, Severe acute respiratory syndrome coronavirus 2, Glycan and Coronavirus. His research in Virology intersects with topics in Epitope, Protein domain and Monoclonal antibody. His Antibody study combines topics from a wide range of disciplines, such as Mutation and Viral replication.
His work in Glycan addresses subjects such as Immune system, which are connected to disciplines such as Protomer. Coronavirus and Middle East respiratory syndrome coronavirus are commonly linked in his work. His study looks at the intersection of Molecular machine and topics like Protein structure with Viral protein.
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Daniel Wrapp;Nianshuang Wang;Kizzmekia S. Corbett;Jory A. Goldsmith.
Science (2020)
Site-specific glycan analysis of the SARS-CoV-2 spike.
Yasunori Watanabe;Yasunori Watanabe;Joel D. Allen;Daniel Wrapp;Jason S. McLellan.
Science (2020)
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman.
Nature (2011)
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.
Kizzmekia S. Corbett;Darin K. Edwards;Sarah R. Leist;Olubukola M. Abiona.
Nature (2020)
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
Jesper Pallesen;Nianshuang Wang;Kizzmekia S. Corbett;Daniel Wrapp.
Proceedings of the National Academy of Sciences of the United States of America (2017)
Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
Jason S. McLellan;Man Chen;M. Gordon Joyce;Mallika Sastry.
Science (2013)
Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody
Jason S. McLellan;Man Chen;Sherman Leung;Kevin W. Graepel.
Science (2013)
Pre-fusion structure of a human coronavirus spike protein
Robert N. Kirchdoerfer;Christopher A. Cottrell;Nianshuang Wang;Jesper Pallesen.
Nature (2016)
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
Ching Lin Hsieh;Jory A. Goldsmith;Jeffrey M. Schaub;Andrea M. DiVenere.
Science (2020)
Immunogenicity of a DNA vaccine candidate for COVID-19.
Trevor R.F. Smith;Ami Patel;Stephanie Ramos;Dustin Elwood.
Nature Communications (2020)
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