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Microbiology

D-Index
87
Citations
43228
World Ranking
777
National Ranking
363

Overview

Jason S. McLellan is affiliated with The University of Texas at Austin in the United States. Their research centers primarily in the field of Medicine, with a significant focus on Infectious Diseases, Epidemiology, and Molecular Biology. Other areas of study include Animal Science and Zoology and Immunology.

The scientist's work covers several main topics, prominently featuring SARS-CoV-2 and COVID-19 research. Additional research interests include viral gastroenteritis research and epidemiology, animal virus infections studies, respiratory viral infections research, bacteriophages and microbial interactions, monoclonal and polyclonal antibodies research, and cytomegalovirus and herpesvirus research.

Jason S. McLellan has contributed to several notable recent papers, including:

  • "Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation" (2020, Science)
  • "Site-specific glycan analysis of the SARS-CoV-2 spike" (2020, Science)
  • "SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness" (2020, Nature)
  • "Structure-based design of prefusion-stabilized SARS-CoV-2 spikes" (2020, Science)
  • "Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein" (2020, ACS Central Science)

Their frequent co-authors include:

  • Daniel Wrapp
  • Ching-Lin Hsieh
  • Barney S. Graham
  • Ralph S. Baric
  • Nianshuang Wang

Jason S. McLellan's work is frequently published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • UNC Libraries
  • Science
  • Cell Reports

Best Publications

  • Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

    Daniel Wrapp;Nianshuang Wang;Kizzmekia S. Corbett;Jory A. Goldsmith

  • SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

    Kizzmekia S. Corbett;Darin K. Edwards;Sarah R. Leist;Olubukola M. Abiona

  • Site-specific glycan analysis of the SARS-CoV-2 spike.

    Yasunori Watanabe;Yasunori Watanabe;Joel D. Allen;Daniel Wrapp;Jason S. McLellan

  • Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

    Ching Lin Hsieh;Jory A. Goldsmith;Jeffrey M. Schaub;Andrea M. DiVenere

  • Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

    Jesper Pallesen;Nianshuang Wang;Kizzmekia S. Corbett;Daniel Wrapp

  • Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

    Jason S. McLellan;Man Chen;M. Gordon Joyce;Mallika Sastry

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  • Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein

    Lorenzo Casalino;Zied Gaieb;Jory A. Goldsmith;Christy K. Hjorth

  • Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

    Jason S. McLellan;Man Chen;Sherman Leung;Kevin W. Graepel

  • Pre-fusion structure of a human coronavirus spike protein

    Robert N. Kirchdoerfer;Christopher A. Cottrell;Nianshuang Wang;Jesper Pallesen

  • Immunogenicity of a DNA vaccine candidate for COVID-19.

    Trevor R.F. Smith;Ami Patel;Stephanie Ramos;Dustin Elwood

  • Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

    Daniel Wrapp;Dorien De Vlieger;Kizzmekia S. Corbett;Gretel M. Torres

  • Broad neutralization of SARS-related viruses by human monoclonal antibodies.

    Anna Z. Wec;Daniel Wrapp;Andrew S. Herbert;Daniel P. Maurer

  • Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.

    Robert N. Kirchdoerfer;Nianshuang Wang;Jesper Pallesen;Daniel Wrapp;Daniel Wrapp

  • Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

    Jason S. McLellan;Yongping Yang;Barney S. Graham;Peter D. Kwong

  • Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2

    Morgane Rolland;Paul T. Edlefsen;Brendan B. Larsen;Sodsai Tovanabutra

  • The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

    Natalie I Mazur;Deborah Higgins;Marta C Nunes;José A Melero

  • Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

    Joan O. Ngwuta;Man Chen;Kayvon Modjarrad;Kayvon Modjarrad;M. Gordon Joyce

  • Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

    Hua Xin Liao;Mattia Bonsignori;S. Munir Alam;Jason S. McLellan

  • The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.

    Bryan E. Jones;Patricia L. Brown-Augsburger;Kizzmekia S. Corbett;Kathryn Westendorf

  • Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

    Ching-Lin Hsieh;Jory A Goldsmith;Jeffrey M Schaub;Andrea M DiVenere

  • Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

    Jason McLellan

Frequent Co-Authors

Barney S. Graham
Barney S. Graham Morehouse School of Medicine
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Yongping Yang
Yongping Yang National Institutes of Health
John R. Mascola
John R. Mascola ModeX Therapeutics
Kizzmekia S. Corbett
Kizzmekia S. Corbett Harvard University
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Ivelin S. Georgiev
Ivelin S. Georgiev Vanderbilt University Medical Center
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill
Tongqing Zhou
Tongqing Zhou National Institutes of Health

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