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Masamichi Ishiai

Masamichi Ishiai

D-Index & Metrics

Molecular Biology

D-Index
43
Citations
5745
World Ranking
2988
National Ranking
217

Overview

Masamichi Ishiai is affiliated with Kyoto University in Japan. Their research primarily focuses on fields spanning Biochemistry, Genetics and Molecular Biology, and Medicine. Within these disciplines, Ishiai's work covers several subfields including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Oncology, Materials Chemistry, and Radiation.

The main topics addressed in Ishiai's publications include:

  • DNA Repair Mechanisms
  • Boron Compounds in Chemistry
  • Radiopharmaceutical Chemistry and Applications
  • Nuclear Physics and Applications
  • PARP inhibition in cancer therapy
  • DNA and Nucleic Acid Chemistry
  • Radiation Therapy and Dosimetry

Selected recent papers authored or co-authored by Ishiai include:

  • "Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination," published in 2021 in Genes
  • "Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair," published in 2021 in International Journal of Molecular Sciences
  • "USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA-RNA helicase DHX9," published in 2020 in Oncogenesis
  • "The FHA domain of PNKP is essential for its recruitment to DNA damage sites and maintenance of genome stability," published in 2020 in Mutation research. Fundamental and molecular mechanisms of mutagenesis
  • "RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination," published in 2020 in Molecular Cell

Ishiai has frequently published in journals including:

  • Journal of Radiation Research
  • Applied Radiation and Isotopes
  • International Journal of Molecular Sciences
  • Oncogenesis
  • Genes

Their collaborative network features frequent co-authors such as:

  • Mitsuko Masutani
  • Shoji Imamichi
  • Hiroshi Igaki
  • Satoshi Nakamura
  • Mikio Shimada

Best Publications

  • BLNK Required for Coupling Syk to PLCγ2 and Rac1-JNK in B Cells

    Masamichi Ishiai;Mari Kurosaki;Rajita Pappu;Katsuya Okawa

  • FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

    Masamichi Ishiai;Hiroyuki Kitao;Hiroyuki Kitao;Hiroyuki Kitao;Agata Smogorzewska;Junya Tomida

  • Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non-Small Cell Lung Cancer Cell Line

    Atsuko Ogino;Hiroyuki Kitao;Seiki Hirano;Seiki Hirano;Akiko Uchida

  • Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells

    Kuniharu Nojima;Helfrid Hochegger;Alihossein Saberi;Toru Fukushima

  • Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia

    Kerstin Knies;Shojiro Inano;María J. Ramírez;Masamichi Ishiai

  • Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation.

    Kazunori Inabe;Masamichi Ishiai;Andrew M. Scharenberg;Norman Freshney

  • FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway.

    Chen Ling;Masamichi Ishiai;Abdullah Mahmood Ali;Annette L Medhurst

  • Fanconi Anemia FANCG Protein in Mitigating Radiation- and Enzyme-Induced DNA Double-Strand Breaks by Homologous Recombination in Vertebrate Cells

    Kazuhiko Yamamoto;Masamichi Ishiai;Nobuko Matsushita;Hiroshi Arakawa

  • RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.

    Shojiro Inano;Koichi Sato;Yoko Katsuki;Wataru Kobayashi

  • Fanconi Anemia Protein FANCD2 Promotes Immunoglobulin Gene Conversion and DNA Repair through a Mechanism Related to Homologous Recombination

    Kazuhiko Yamamoto;Seiki Hirano;Masamichi Ishiai;Kenichi Morishima

  • A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair

    Nobuko Matsushita;Hiroyuki Kitao;Masamichi Ishiai;Naoki Nagashima

  • BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins.

    Christopher W. Chiu;Mark Dalton;Masamichi Ishiai;Tomohiro Kurosaki

  • Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Crosslinks

    Kohei Nishimura;Masamichi Ishiai;Kazuki Horikawa;Tatsuo Fukagawa

  • Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.

    Seiki Hirano;Kazuhiko Yamamoto;Kazuhiko Yamamoto;Masamichi Ishiai;Mitsuyoshi Yamazoe

  • Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells.

    Nobuko Matsushita;Yasunari Takami;Masayo Kimura;Seiji Tachiiri

  • B Cell Antigen Receptor Engagement Inhibits Stromal Cell–derived Factor (SDF)-1α Chemotaxis and Promotes Protein Kinase C (PKC)-induced Internalization of CXCR4

    Rodolphe Guinamard;Nathalie Signoret;Masamichi Ishiai;Mark Marsh

  • Cutting edge: association of phospholipase C-gamma 2 Src homology 2 domains with BLNK is critical for B cell antigen receptor signaling.

    Masamichi Ishiai;Hitoshi Sugawara;Mari Kurosaki;Tomohiro Kurosaki

  • Crystal structure of a prokaryotic replication initiator protein bound to DNA at 2.6 Å resolution

    Hirofumi Komori;Fujihiko Matsunaga;Yoshiki Higuchi;Masamichi Ishiai

  • Predisposition to cancer caused by genetic and functional defects of mammalian Atad5.

    Daphne W. Bell;Nilabja Sikdar;Kyoo-young Lee;Jessica C. Price

  • DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI

    Koichi Sato;Kazue Toda;Masamichi Ishiai;Minoru Takata

Frequent Co-Authors

Minoru Takata
Minoru Takata Kyoto University
Tomohiro Kurosaki
Tomohiro Kurosaki Osaka University
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Takashi Yura
Takashi Yura Kyoto University
Takemi Enomoto
Takemi Enomoto Musashino University
Shunichi Takeda
Shunichi Takeda Shenzhen University
Akifumi Takaori-Kondo
Akifumi Takaori-Kondo Kyoto University
Toshiaki Isobe
Toshiaki Isobe Tokyo Metropolitan University
Detlev Schindler
Detlev Schindler University of Würzburg

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