What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
Andrew C. Chan focuses on Immunology, Cell biology, Autoimmunity, Immune system and Antibody.
His Immunology research focuses on CD20 in particular.
Andrew C. Chan usually deals with CD20 and limits it to topics linked to Disease and T cell.
His Cell biology study combines topics in areas such as Receptor, T lymphocyte and IL-2 receptor.
His research in Autoimmunity tackles topics such as Autoantibody which are related to areas like Immunity and Immunotherapy.
His work in the fields of Antibody, such as Anti cd20 antibody, overlaps with other areas such as First generation.
His most cited work include:
- Therapeutic antibodies for autoimmunity and inflammation (777 citations)
- Immunoglobulin variants and uses thereof (668 citations)
- Activation of human CD4 + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype (505 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Immunology, Immune system, Antibody and Signal transduction are his primary areas of study.
His study in Cell biology is interdisciplinary in nature, drawing from both Receptor and T cell, T-cell receptor.
In most of his Immunology studies, his work intersects topics such as Disease.
The Immune system study combines topics in areas such as Tumor necrosis factor alpha, In silico, Computational biology and Regulatory B cells.
His Antibody research is multidisciplinary, incorporating perspectives in Molecular biology and Sequence.
As part of the same scientific family, he usually focuses on Signal transduction, concentrating on Endosome and intersecting with Internalization.
He most often published in these fields:
- Cell biology (36.07%)
- Immunology (32.79%)
- Immune system (24.59%)
What were the highlights of his more recent work (between 2014-2020)?
- Protein tyrosine phosphatase (14.75%)
- PTPN22 (13.11%)
- Cell biology (36.07%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Protein tyrosine phosphatase, PTPN22, Cell biology, Immunology and Immune system.
Andrew C. Chan combines subjects such as Inflammasome, Colitis, Gut flora and Tyrosine phosphorylation with his study of Protein tyrosine phosphatase.
His research integrates issues of Downregulation and upregulation and Cytokine in his study of Cell biology.
Andrew C. Chan undertakes multidisciplinary studies into Immunology and Anti cd20 in his work.
His Immune system study incorporates themes from Signal transduction and B cell, Regulatory B cells.
Andrew C. Chan has researched Signal transduction in several fields, including Receptor, Autoimmunity and Interferon, Alpha interferon.
Between 2014 and 2020, his most popular works were:
- NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 (115 citations)
- PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner (39 citations)
- Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease (38 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cytokine
Andrew C. Chan spends much of his time researching Receptor, Cell biology, Phosphorylation, Tyrosine phosphorylation and PTPN22.
His work deals with themes such as Antigen, Guanine nucleotide exchange factor, Signal transduction, T-cell receptor and Effector, which intersect with Receptor.
His biological study spans a wide range of topics, including Downregulation and upregulation and Immune system.
His research in Phosphorylation intersects with topics in Pyrin domain, Inflammasome and Cancer research.
His Tyrosine phosphorylation research is multidisciplinary, incorporating elements of Autophagy, Secretion, Receptor tyrosine kinase and Intracellular.
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